Tue, Oct-04-11, 12:35
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Plan: Muscle Centric
Stats: 238/153/160
BF:
Progress: 109%
Location: UK
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Thin parents pass on 'skinny genes' to children
Quote:
From The Independent
London, UK
4 October, 2011
Thin parents pass on 'skinny genes' to children
Children whose parents are thin are likely to be very slim themselves due to "skinny genes", new research suggests.
Youngsters whose parents are at the lower end of the healthy weight range are three times more likely to be regarded as thin (weighing less than a healthy weight range) than those whose parents are overweight.
The study recorded the height and weight of parents and up to two children from 7,000 families over a five-year period.
Analysis of body mass index (BMI) found that when both parents were at the lower half of the ideal BMI range, the chance of the child being thin was 16.2%, compared with 7.8% when both parents were in the upper half.
These children had a BMI of 18.5 or under (regarded as "thin"), compared with a healthy weight range of 18.5 to 24.9. A BMI of 25 to 29.9 is overweight and over 30 is obese.
The study found that the chance of a child being thin (BMI under 18.5) was just 5.3% when both parents were overweight and only 2.5% for children whose parents were obese.
Today's study, published in the journal Archives of Pediatrics and Adolescent Medicine, suggests thinness may be inherited, with children of thinner parents being likely to be genetically predisposed to a lower body weight.
Lead author Dr Katriina Whitaker, from University College London's department of epidemiology and public health, said: "We know from other studies that children's weights are correlated with those of their parents, but previous research has tended to focus on obesity rather than the other end of the spectrum."
Professor Jane Wardle, from the same unit, added: "Parents are often concerned if their child is thin, but it may just be their 'skinny genes'.
"All genes have two versions, called alleles.
"We might think of weight-related genes as having a 'skinny' and 'curvy' allele.
"Thinner parents are likely to have more of the skinny alleles, increasing the chance of passing them on to their children.
"A child who inherits more of the skinny alleles from their parents will be naturally thinner."
The researchers concluded: "These results are consistent with the idea that many cases of thinness are likely to represent the low end of the healthy distribution of weight and, as such, are likely to have a primarily genetic origin."
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http://www.independent.co.uk/life-s...en-2365307.html
Quote:
Vol. 165 No. 10, October 2011
The Intergenerational Transmission of Thinness
Katriina L. Whitaker, PhD; Martin J. Jarvis, DSc; David Boniface, PhD; Jane Wardle, PhD
Arch Pediatr Adolesc Med. 2011;165(10):900-905. doi:10.1001/archpediatrics.2011.147
Objectives To examine intergenerational associations for thinness and to compare maternal and paternal effects.
Design Population-based, cross-sectional design using data from the Health Survey for England from January 1, 2001, through December 31, 2006.
Setting The Health Survey for England, an annual, national survey representative of the population living in private households in England.
Participants Families with children and adolescents aged 2 to 15 years with anthropometric data available for children and adolescents and 2 parents (N = 4423 families, N = 7078 children and adolescents).
Main Exposure Trained interviewers collected height and weight measurements.
Main Outcome Measure Child/adolescent thinness, categorized using International Obesity Task Force criteria.
Results Of 7078 children and adolescents, 402 (5.7%) were categorized as being thin. Thinness was more common in 2- to 5-year-olds (odds ratio, 1.61; 95% confidence interval, 1.22-2.13) than in 11- to 15-year-olds and in children and adolescents from ethnic minority (black: 2.28; 1.22-4.26; and Asian: 3.65; 2.76-4.83) than white backgrounds, but no differences were observed by sex or socioeconomic status. The strongest predictor of child/adolescent thinness was parental weight status. The prevalence of thinness was highest (16.2%) when both parents were thinner and progressively lower when both parents were in the upper half of the healthy-weight range (7.8%) or were overweight (5.3%) or obese (2.5%), with no differences in the magnitude of maternal and paternal influences.
Conclusions These results are consistent with the idea that many cases of thinness are likely to represent the low end of the healthy distribution of weight and, as such, are likely to have a primarily genetic origin.
Author Affiliations: Health Behaviour Research Centre, Department of Epidemiology and Public Health, University College London, London, England.
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http://archpedi.ama-assn.org/cgi/co...hort/165/10/900
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