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  #1   ^
Old Sat, Sep-06-08, 17:40
alisbabe's Avatar
alisbabe alisbabe is offline
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Default High carb diet linked to neurological damage

Quote:
High carb diet linked to neurological damage

High-carb diet attacks satiety
Michele Thompson, MS

Do you know your high carb, high sugar diet could be damaging your brain cells? Worse, this damage could be a major factor in adult-onset weight gain. Learn why you should ditch your high carb consumption and follow a diet rich in lean proteins and healthy fats and a modest intake of complex carbohydrates.

A diet high in carbs damages your appetite-control center

Research in the journal Nature reports more bad news on high carb diets. Dr. Ane Andrews, a neuroendocrinologist with Monash University’s Department of Physiology, found that the appetite-suppressing cells in the brain are attacked by free radicals after eating, significantly so following meals rich in carbohydrates and sugars.

This could be one more reason people tend to gain weight as they get older. More cells are damaged over time, resulting in increased hunger, overconsumption and weight gain. "The more carbs and sugars you eat, the more your appetite-control cells are damaged, and potentially you consume more," says Andrews.

According to Andrews, when the stomach is empty, it triggers the hormone ghrelin, which notifies your brain that you are hungry. Once you eat and become full, a set of neurons known as POMC’s kick in and tell your brain you are sated.

"However, free radicals created naturally in the body attack the POMC neurons. This process causes the neurons to degenerate over time, affecting our judgment as to when our hunger is satisfied," he adds. Free radicals also try to attack the hunger neurons but, unfortunately, they are protected by a protein.

Andrews warns that people aged 25 to 50 are most at risk, particularly if they eat a diet high in carbs and sugars. "A diet rich in carbohydrate and sugar that has become more and more prevalent in modern societies over the last 20 to 30 years has placed so much strain on our bodies that it is leading to premature cell deterioration," he says.

Andrews plans on expanding his research to determine if a diet rich in carbohydrates and sugars has other detrimental effects on the brain, such as neurological changes leading to Parkinson's disease.

Maybe you should consider changing your high carb and high sugar diet before its too late!


http://www.sheknows.com/articles/805544.htm
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  #2   ^
Old Sat, Sep-06-08, 19:33
ceberezin ceberezin is offline
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Default

Basically, good article, but does the stomach's being empty or full really send signals. Isn't the issue whether the cells are getting the nourishment they need that would trigger responses. Someone somewhere has pointed out that there is no such connection between the stomach and the brain.
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  #3   ^
Old Sat, Sep-06-08, 21:34
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Nancy LC Nancy LC is offline
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What about the vagus nerve and various hormones that cause hunger or saiety like PYY, CKK and so on. I'd say there's a hell of a lot of communication between the stomach, intestines and the brain.

http://pen.sagepub.com/cgi/content/abstract/32/5/567 (for one example)
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  #4   ^
Old Sat, Sep-06-08, 23:21
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aj_cohn aj_cohn is offline
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Holy cow! I never thought I'd see this reported in "fluffy" popular media in my lifetime.
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  #5   ^
Old Sun, Sep-07-08, 21:48
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francisstp francisstp is offline
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Quote:
This could be one more reason people tend to gain weight as they get older. More cells are damaged over time, resulting in increased hunger, overconsumption and weight gain. "The more carbs and sugars you eat, the more your appetite-control cells are damaged, and potentially you consume more," says Andrews.


That's a huge "potentially". It's a very common notion that people eat less as they age, not the opposite. If calories alone explained weight gain then teens would be the heaviest and would gradually lose the weight into adulthood and old age. This is not what happens.

It's amazing the number of studies coming up that clearly point to the hormonal hypothesis of obesity yet are reported with a calorie angle. Screw paradigms!
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  #6   ^
Old Mon, Sep-08-08, 00:10
M Levac M Levac is offline
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Default

I think the body works as a collection of individual cells and not as a unit.

I'm hungry not because there's no food in my stomach but instead because my cells send the hunger signal (probably a hormone like leptin or ghrelin) through the bloodstream which in turn transports it to the relevant part of the brain that then speaks to another part of the brain that activates the stomach and intestines to process the food that is about to go in. Once the food is processed and nutrients flow in the bloodstream, cells sense this and stop sending the hunger signal. The brain senses this, hunger subsides and we stop eating.

Carbs short-circuit this mechanism so that we continue eating even though we're way past full. It does so by driving blood glucose which drives insulin which drive fat accumulation. In other words, eating carbs empties the blood of nutrients so cells continuously send the hunger signal until there's enough nutrients in the bloodstream. I think this finally happens when the feeding super-system is simply overloaded or our jaws get tired.

It's only my interpretation of the various mechanisms.
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