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  #1   ^
Old Sat, May-30-20, 18:03
Merpig's Avatar
Merpig Merpig is offline
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Plan: EF/Fung IDM/keto
Stats: 375/238.4/175 Female 66.5 inches
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Progress: 68%
Location: NE Florida
Default Covid and statins

https://elemental.medium.com/corona...ng-2c4032481ab2
Quote:
The good news is that if Covid-19 is a vascular disease, there are existing drugs that can help protect against endothelial cell damage. In another New England Journal of Medicine paper that looked at nearly 9,000 people with Covid-19, Mehra showed that the use of statins and ACE inhibitors were linked to higher rates of survival. Statins reduce the risk of heart attacks not only by lowering cholesterol or preventing plaque, they also stabilize existing plaque, meaning they’re less likely to rupture if someone is on the drugs.

It turns out that both statins and ACE inhibitors are extremely protective on vascular dysfunction,” Mehra says. “Most of their benefit in the continuum of cardiovascular illness — be it high blood pressure, be it stroke, be it heart attack, be it arrhythmia, be it heart failure — in any situation the mechanism by which they protect the cardiovascular system starts with their ability to stabilize the endothelial cells.”

Last edited by Merpig : Sun, May-31-20 at 09:54.
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  #2   ^
Old Sat, May-30-20, 18:34
Bob-a-rama's Avatar
Bob-a-rama Bob-a-rama is offline
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Posts: 1,584
 
Plan: Keto (Atkins Induction)
Stats: 230/171/185 Male 5' 11"
BF:
Progress: 131%
Location: Florida
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I'd suggest yes, they might help, unless you already have an underlying condition that causes you to be on them already.

This from a layman's point of view with no medical education.

The reason being if you are on statins or ACE inhibitors, you already have endothelial problems which is what COVID seems to be attracted to.

Bob
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  #3   ^
Old Sat, May-30-20, 22:52
Zei Zei is online now
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Posts: 1,520
 
Plan: Carb reduction in general
Stats: 230/213/180 Female 5 ft 9 in
BF:
Progress: 34%
Location: Texas
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Statins might exert a tiny positive effect (but not in females) by reducing inflammation, which if so might explain the tiny statistical benefit to some males with prior heart attacks and perhaps have some sort of positive effect on the COVID thing by reducing inflammation. However, I credit statins for causing the condition that killed my MIL, so I won't be signing up for them. Ever.
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  #4   ^
Old Sun, May-31-20, 07:40
BawdyWench's Avatar
BawdyWench BawdyWench is offline
Posts: 7,878
 
Plan: ADMF (500 calories)
Stats: 212/195/160 Female 5'6
BF:Too much!
Progress: 33%
Location: Rural Maine
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Correlation is not causation. I remember a "study" done in a hospital setting regarding heart disease in men. One of the doctors involved didn't think the study was set up well, and so added one more question on the survey, asking about facial hair. Turns out that men with a beard, a mustache, goatee, etc. had less heart disease than men who were clean-shaven. Wow! All guys have to do it s to grow a beard and they won't have heart disease!
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  #5   ^
Old Sun, May-31-20, 08:01
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WereBear WereBear is offline
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Plan: Epi-Paleo/IF
Stats: 220/123/150 Female 67
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Location: USA
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Quote:
Originally Posted by Zei
Statins might exert a tiny positive effect (but not in females) by reducing inflammation, which if so might explain the tiny statistical benefit to some males with prior heart attacks and perhaps have some sort of positive effect on the COVID thing by reducing inflammation. However, I credit statins for causing the condition that killed my MIL, so I won't be signing up for them. Ever.


Their tiny positive effect is far outweighed by the staggering risk of the side effects.
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  #6   ^
Old Sun, May-31-20, 09:09
Bob-a-rama's Avatar
Bob-a-rama Bob-a-rama is offline
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Plan: Keto (Atkins Induction)
Stats: 230/171/185 Male 5' 11"
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Quote:
Originally Posted by BawdyWench
Correlation is not causation. I remember a "study" done in a hospital setting regarding heart disease in men. One of the doctors involved didn't think the study was set up well, and so added one more question on the survey, asking about facial hair. Turns out that men with a beard, a mustache, goatee, etc. had less heart disease than men who were clean-shaven. Wow! All guys have to do it s to grow a beard and they won't have heart disease!

I'm proof of that. I'm 73 with according to a heart doctor I have a circulatory system of a 50 year old.

Of course eating mostly non-proceeded food, walking 3-4 miles briskly almost every day, having a fun and loving relationship with my wife, loving my career, and living a relatively stress free live had nothing to do with it. It's the facial hair.

Bob
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  #7   ^
Old Sun, May-31-20, 09:46
Merpig's Avatar
Merpig Merpig is offline
Posts: 6,937
 
Plan: EF/Fung IDM/keto
Stats: 375/238.4/175 Female 66.5 inches
BF:
Progress: 68%
Location: NE Florida
Default

Quote:
Originally Posted by Zei
Statins might exert a tiny positive effect (but not in females) by reducing inflammation, which if so might explain the tiny statistical benefit to some males with prior heart attacks and perhaps have some sort of positive effect on the COVID thing by reducing inflammation. However, I credit statins for causing the condition that killed my MIL, so I won't be signing up for them. Ever.
I agree with you there and to this day feel statins comtributed to the death of my father too. My dad was a T2 diabetic but well controlled with metformin alone, had BP of about 110/65, cholesterol was about 205 with great ratios - and at 75 was still quite fit, hale and hearty. The cardiologist said he had an amazingly strong heart. But his doctor INSISTED he go on statins because he was a T2 diabetic and had "high" cholesterol. He was of the generation that believed doctors were always right and never questioned what he was told so he took them.

And within MONTHS he turned from a hale 75-year-old to a little shriveled old man - stooped over, muscle aches all the time, memory issues. He developed congestive heart failure (one of the possible statin side effects). All within SIX MONTHS.

I was stupid in those days and could not put the pieces together but my sister, bless her, did a lot of research and concluded that it was due to the statins. She begged him to stop taking them but he never questioned the "doctor says" and said why would be trust her instead of his doctor?

But again, bless my sister, she eventually even went to his doctor herself and more or less managed to pressure him into agreeing to stop the prescription, and only then did my dad agree to stop taking them.

Once he did he did slowly begin to improve, but he never again regained the health he had had before he began taking them. He did live almost seven more years, dying shortly before his 82nd birthday, but my sister and I both still feel that the statins were still the "beginning of the end". He was always a frail little old man from that point on.

Last edited by Merpig : Sun, May-31-20 at 09:53.
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  #8   ^
Old Mon, Jun-01-20, 05:00
BawdyWench's Avatar
BawdyWench BawdyWench is offline
Posts: 7,878
 
Plan: ADMF (500 calories)
Stats: 212/195/160 Female 5'6
BF:Too much!
Progress: 33%
Location: Rural Maine
Default

Debbie, it's so heartbreaking to hear that about your father. That generation always listened to their doctors. I think it's really been our generation that started to question things. My sister in Michigan, who is disabled and lives in a group home, has a doctor who insists on giving her statins. I've argued and argued, and at least got her to change to the generic for Crestor because it doesn't stay in your system like some of the others do.
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