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  #1   ^
Old Wed, Aug-28-19, 12:32
Demi's Avatar
Demi Demi is offline
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Plan: LCHF/IF
Stats: 217/182/160 Female 5'10"
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Default Association of Cereal & Gluten Intake With Islet Autoimmunity and Type 1 Diabetes

Quote:
Association of Cereal, Gluten, and Dietary Fiber Intake With Islet Autoimmunity and Type 1 Diabetes

Abstract


Importance Dietary proteins, such as gluten, have been suggested as triggers of the disease process in type 1 diabetes (T1D).

Objective To study the associations of cereal, gluten, and dietary fiber intake with the development of islet autoimmunity (IA) and T1D.

Design, Setting, and Participants The prospective birth cohort Finnish Type 1 Diabetes Prediction and Prevention Study recruited children with genetic susceptibility to type 1 diabetes from September 1996 to September 2004 from 2 university hospitals in Finland and followed up every 3 to 12 months up to 6 years for diet, islet autoantibodies, and T1D. Altogether 6081 infants (78% of those invited) participated in the study. Dietary data were available for 5714 children (94.0%) and dietary and IA data were available for 5545 children (91.2%), of whom 3762(68%) had data on islet autoantibodies up to age 6 years. Information on T1D was available for all children. Data were analyzed in 2018 and end point data were updated in 2015.

Exposures Each child’s intake of cereals, gluten, and dietary fiber was calculated from repeated 3-day food records up to 6 years.

Main Outcomes and Measures Islet autoimmunity was defined as repeated positivity for islet cell antibodies and at least 1 biochemical autoantibody of 3 analyzed, or T1D. Data on the diagnosis of T1D were obtained from Finnish Pediatric Diabetes Register.

Results Of 5545 children (2950 boys [53.2%]), 246 (4.4%) developed IA and of 5714 children (3033 boys [53.1%]), 90 (1.6%) developed T1D during the 6-year follow-up. Based on joint models, the intake of oats (hazard ratio [HR], 1.08; 95% CI, 1.03-1.13), wheat (HR, 1.09; 95% CI, 1.03-1.15), rye (HR, 1.13; 95% CI, 1.03-1.23), gluten-containing cereals (HR, 1.07; 95% CI, 1.03-1.11), gluten without avenin from oats (HR, 2.23; 95% CI, 1.40-3.57), gluten with avenin (HR, 2.06; 95% CI, 1.45-2.92), and dietary fiber (HR, 1.41; 95% CI, 1.10-1.81) was associated with the risk of developing IA (HRs for 1 g/MJ increase in intake). The intake of oats (HR, 1.10; 95% CI, 1.00-1.21) and rye (HR, 1.20; 95% CI, 1.03-1.41) was associated with the risk of developing T1D. After multiple testing correction, the associations with IA remained statistically significant.

Conclusions and Relevance A high intake of oats, gluten-containing cereals, gluten, and dietary fiber was associated with an increased risk of IA. Further studies are needed to confirm or rule out the findings and study potential mechanisms.


https://jamanetwork.com/journals/ja...bstract/2748382
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  #2   ^
Old Wed, Aug-28-19, 12:43
Ms Arielle's Avatar
Ms Arielle Ms Arielle is offline
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Plan: atkins
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Hmmmm......my understanding was it is milk that triggers t1D.... contains a protein very similar to proteins in the Islets of Langerhan.

How many of these kids have cows milk with their cereal ???
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  #3   ^
Old Wed, Sep-04-19, 04:22
WereBear's Avatar
WereBear WereBear is online now
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Plan: Epi-Paleo/IF
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It can all work together to up someone's risk.
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  #4   ^
Old Wed, Sep-04-19, 08:19
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khrussva khrussva is offline
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Plan: My own - < 30 net carbs
Stats: 440/213/210 Male 5' 11"
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Default

Why is it that when an observational study that comes up with a knock in any way against meat the headlines ring with "meat is killing you" hype at every turn. But when grains are the bad guy, the conclusion is that further study is needed.
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  #5   ^
Old Wed, Sep-04-19, 09:00
CityGirl8 CityGirl8 is offline
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Plan: Protein Power, IF
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Quote:
Originally Posted by khrussva
Why is it that when an observational study that comes up with a knock in any way against meat the headlines ring with "meat is killing you" hype at every turn. But when grains are the bad guy, the conclusion is that further study is needed.
Well, because the first studies are confirming what we already know and the latter studies are at odds with the true facts. Obvi.
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  #6   ^
Old Wed, Sep-04-19, 09:09
Ms Arielle's Avatar
Ms Arielle Ms Arielle is offline
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Plan: atkins
Stats: 255/214/153 Female 5'8"
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Progress: 40%
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Quote:
Originally Posted by khrussva
Why is it that when an observational study that comes up with a knock in any way against meat the headlines ring with "meat is killing you" hype at every turn. But when grains are the bad guy, the conclusion is that further study is needed.

Yup, the powers that be are fighting the inevitable.
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  #7   ^
Old Thu, Sep-05-19, 04:56
WereBear's Avatar
WereBear WereBear is online now
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Plan: Epi-Paleo/IF
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They don't want the legal liability.
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  #8   ^
Old Thu, Sep-05-19, 06:45
Ms Arielle's Avatar
Ms Arielle Ms Arielle is offline
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Plan: atkins
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Government entities cannot be sued for money.
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  #9   ^
Old Thu, Sep-05-19, 09:12
WereBear's Avatar
WereBear WereBear is online now
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Plan: Epi-Paleo/IF
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But corporations can. Imagine a class action suit brought by the people of Western Civilization.
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  #10   ^
Old Thu, Sep-05-19, 10:20
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GRB5111 GRB5111 is offline
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Plan: Ketogenic (LCHFKD)
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That's exactly why many of these corporations are actively funding epidemiological studies that reek of selection bias. Convenient to hide the results they don't want. Guess they missed this one.
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  #11   ^
Old Thu, Sep-05-19, 10:38
Ms Arielle's Avatar
Ms Arielle Ms Arielle is offline
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Plan: atkins
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Quote:
Originally Posted by WereBear
But corporations can. Imagine a class action suit brought by the people of Western Civilization.


yes.

But what is the governments reasoning for NOT seeing the real picture given the vat amounts of research findings in the last few years??????

Imo, if the gov changes, the companies will be wide open to suits......what is the economic outcome of that...? IMO government is taking protective action.

Maybe Im wrong. Ive become a cynic.....
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  #12   ^
Old Thu, Sep-05-19, 15:20
Zei Zei is offline
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Quote:
Originally Posted by Ms Arielle
yes.

But what is the governments reasoning for NOT seeing the real picture given the vat amounts of research findings in the last few years??????

My first thought that comes up is...follow the money?
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  #13   ^
Old Fri, Sep-06-19, 05:27
WereBear's Avatar
WereBear WereBear is online now
Posts: 11,891
 
Plan: Epi-Paleo/IF
Stats: 220/123/150 Female 67
BF:
Progress: 139%
Location: USA
Default

We also must remember that we are "turning a battleship." Something this size can't turn on a dime. The fat phobia itself took time to build and spread.

Without admitting they were so spectacularly wrong, this can be pinned on "further research revealed" over decades.

It's no wonder Semmelweis wound up in an insane asylum.
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  #14   ^
Old Fri, Sep-06-19, 05:54
Ms Arielle's Avatar
Ms Arielle Ms Arielle is offline
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Plan: atkins
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ITs the biggest fraud case in the history of mankind. AND it eats billions, trillions from the economy in health care that could be better used to enlighten our people......
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