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  #91   ^
Old Thu, Apr-11-19, 09:12
Ms Arielle's Avatar
Ms Arielle Ms Arielle is offline
Senior Member
Posts: 11,042
 
Plan: atkins
Stats: 247/217/153 Female 5'8"
BF:
Progress: 32%
Location: Massachusetts
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One thing led to another....

https://feinmantheother.com/2016/10...dies-will-help/


Quote:
Drugs employed as diabetes therapy, particularly metformin, have been found to have beneficial effects in cancer as well. Metformin reduces the risk of developing cancer although the effects on mortality are not clear cut.




Quote:
We cited an important study by Tannenbaum. He found, in 1945 (!) that a carcinogen-induced sarcoma in mice was repressed by reduction in total calories but if reduced by specifically lowering the carbohydrate intake, there was an enhanced response.


Quote:
It is now appreciated that the Warburg effect, the apparent reliance of tumors on glucose for fuel, is a key observation that has been insufficiently explored. The effect provides motivation and clues for exploring the metabolic approach to cancer. Warburg thought that all cancers showed this phenotype which is not true but a large number do; of significance is that one that does not, prostate cancer, is the outlier in the figure above on relation to diabetes.
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  #92   ^
Old Thu, Apr-11-19, 09:21
Ms Arielle's Avatar
Ms Arielle Ms Arielle is offline
Senior Member
Posts: 11,042
 
Plan: atkins
Stats: 247/217/153 Female 5'8"
BF:
Progress: 32%
Location: Massachusetts
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Biochemistry of energy use in layman's terms.

https://feinmantheother.com/2016/11...ies-might-help/


Quote:
We found that if you grow cancer cells in culture, ketone bodies will inhibit their growth and the amount of ATP that they can generate.




More explanation of energy use by cells--

https://feinmantheother.com/2016/12...warburg-effect/

Quote:
if we grow cancer cells in culture, acetoacetate (one of the ketone bodies) will inhibit their growth and will reduce the amount of ATP that they can generate. Normal cells, however, are not inhibited by ketone bodies and the cells may even be using them. Our working explanation is that the ketone bodies are inhibiting the cancer cell through the Randle cycle. Now, normal cells can maintain energy, that is compensate for the Randle cycle, by running the TCA cycle (in fact, that is the purpose of the Randle cycle: to switch fuel sources). The cancer cells, however, have some kind of defect in aerobic metabolism and canít compensate. How does this happen? Thatís what weíre trying to find out but we have a good guess.


THses three blogs were posted in 2016.
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  #93   ^
Old Tue, Jun-04-19, 08:38
TammyD's Avatar
TammyD TammyD is offline
Senior Member
Posts: 417
 
Plan: Gluten-free/Low Carb/IF
Stats: 250/230/175 Female 5'8"
BF:?
Progress: 27%
Location: Dartmouth Nova Scotia
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Thank-you Ms A., There is a lot to think about in this thread.
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  #94   ^
Old Wed, Jun-12-19, 08:13
Ms Arielle's Avatar
Ms Arielle Ms Arielle is offline
Senior Member
Posts: 11,042
 
Plan: atkins
Stats: 247/217/153 Female 5'8"
BF:
Progress: 32%
Location: Massachusetts
Default

You're welcome.

This is a journey..... solid information is slow to come by.

Talked to my mother the other day-- she is still solidly on board with chemo and radiation..... I dont think she can see how much her quick mind has slowed; it was obvious after the cancer treatment.

Praying methodology of treatments will improve as fast as possible.
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  #95   ^
Old Wed, Jun-12-19, 08:24
JEY100's Avatar
JEY100 JEY100 is offline
To Good Health!
Posts: 11,152
 
Plan: IF Fung/LC Westman/Primal
Stats: 222/171/169 Female 5' 9"
BF:45%/25.3%/24%
Progress: 96%
Location: NC
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Quote:
Originally Posted by Ms Arielle
You're welcome.

This is a journey..... solid information is slow to come by.

Talked to my mother the other day-- she is still solidly on board with chemo and radiation..... I dont think she can see how much her quick mind has slowed; it was obvious after the cancer treatment.


Chemo Brain to us lay folk, the Doctors call it Cognitive Dysfunction
https://www.cancer.net/coping-with-...memory-problems Their strategies for coping with it limited, but maybe some of these will help.


Dr. Cantley's talk was yesterday, but as usual with these on-line summits, there should be a bonus day after Friday. He has some brand new studies on sugar and cancer. https://forum.lowcarber.org/showthread.php?t=482615
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  #96   ^
Old Wed, Jun-12-19, 09:34
Ms Arielle's Avatar
Ms Arielle Ms Arielle is offline
Senior Member
Posts: 11,042
 
Plan: atkins
Stats: 247/217/153 Female 5'8"
BF:
Progress: 32%
Location: Massachusetts
Default

Thanks Janet-- watching NOW. Missed the first couple days, dang, but Dr Noakes gave a very good synopsis of his adventures into low carbing.

Thank goodness for those that have the courage and will to stand up to the nay-sayers of low carb diets.
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