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  #1   ^
Old Fri, Mar-08-13, 15:48
RawNut's Avatar
RawNut RawNut is offline
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Default The Clue to Why Low Fat Diet and Statins may Cause Alzheimer’s

By Dr. Stephanie Seneff

Too long to copy and past so I'm just pasting the abstract:

Quote:
Abstract

Alzheimer’s is a devastating disease whose incidence is clearly on the rise in America. Fortunately, a significant number of research dollars are currently being spent to try to understand what causes Alzheimer’s. ApoE-4, a particular allele of the apolipoprotein apoE, is a known risk factor. Since apoE plays a critical role in the transport of cholesterol and fats to the brain, it can be hypothesized that insufficient fat and cholesterol in the brain play a critical role in the disease process. In a remarkable recent study, it was found that Alzheimer’s patients have only 1/6 of the concentration of free fatty acids in the cerebrospinal fluid compared to individuals without Alzheimer’s. In parallel, it is becoming very clear that cholesterol is pervasive in the brain, and that it plays a critical role both in nerve transport in the synapse and in maintaining the health of the myelin sheath coating nerve fibers. An extremely high-fat (ketogenic) diet has been found to improve cognitive ability in Alzheimer’s patients. These and other observations described below lead me to conclude that both a low-fat diet and statin drug treatment increase susceptibility to Alzheimer’s.


http://healthimpactnews.com/2012/th...use-alzheimers/
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  #2   ^
Old Fri, Mar-08-13, 15:53
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Nancy LC Nancy LC is offline
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Wow! That should have created quite a news story... but it probably won't.
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  #3   ^
Old Fri, Mar-08-13, 21:54
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Katfishy Katfishy is offline
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Wow! That was a heavy article but well worth the read. I think this theory is particularly compelling because it unifies several very different observations of Alzheimer's brains (amyloid-beta plaques deposited in the brain, increased viruses and bacteria infecting the brain, reduced levels of cholesterol and fatty acids in the cerebrospinal fluid) and explains how they can all be caused by cholesterol/fat deficiencies.

It's particularly scary to think that some people might have developed high cholesterol as a defense AGAINST Alzheimer's and then took statins which stripped away their natural defense.
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  #4   ^
Old Sat, Mar-09-13, 08:25
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WereBear WereBear is offline
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Quote:
Originally Posted by Katfishy
It's particularly scary to think that some people might have developed high cholesterol as a defense AGAINST Alzheimer's and then took statins which stripped away their natural defense.


Yes. This.

I predict the whole cholesterol scare will eventually be as BIG a deal of medical malpractice as doctors washing their hands, which was a very tough sell.

http://en.wikipedia.org/wiki/Semmelweiss

Dr. Semmelweiss went crazy (I think because people were dying and no one was listening to him) and died in the asylum of (ironically) poor medical care.

I think we all know how he must have felt.
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  #5   ^
Old Sat, Mar-09-13, 10:42
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Maerow Maerow is offline
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That was a hard but incredibly insightful read! Just more fuel on the small but growing fire that will eventually end the belief that low fat diets are healthy. How insane the hate campaign against cholesterol will seem when people look back at this time in history.
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  #6   ^
Old Mon, Mar-11-13, 10:20
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keith v keith v is offline
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Wow thats a great, if tragic, story, History does repeat itself!
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  #7   ^
Old Fri, Mar-15-13, 19:06
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Cleome Cleome is offline
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Here is a direct link

APOE-4: The Clue to Why Low Fat Diet and Statins
may Cause Alzheimer's


by Stephanie Seneff

seneff~csail.mit.edu
December 15, 2009
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