How are the optimal levels of vitamin D different between men and women?

I have often wondered if women require a lot more vitamin D - hence they are always wanting to lay out in the sun.

The only natural difference between men and women vitamin D requirements that I can find are due to pregnancy and lactation, women need more then because they are providing the vitamin D for themselves and an infant at the same time.

All other differences in vitamin D production and therefore difficulty filling of D requirements naturally and thus requiring greater supplementation are cultural and environmental. Women, IMO, are naturally indoors more than men. Certainly in most environments they are more covered, less skin exposed than men.

Then count me in on supporting your cause to help women take more off !

I'm sorry I shouldn't take cheap shots when you are doing something serious.

Vitamin D and Breast Cancer

http://www.ncbi.nlm.nih.gov/entrez/...QuerySuggestion

1:
Milliken EL, Zhang X, Flask C, Duerk JL, Macdonald PN, Keri RA.
Related Articles, Links


EB1089, a vitamin D receptor agonist, reduces proliferation and decreases tumor growth rate in a mouse model of hormone-induced mammary cancer.
Cancer Lett. 2005 Nov 18;229(2):205-15. Epub 2005 Aug 22.
PMID: 16115727 [PubMed - in process]
2:
Sergeev IN.
Related Articles, Links


Calcium signaling in cancer and vitamin D.
J Steroid Biochem Mol Biol. 2005 Aug 1; [Epub ahead of print]
PMID: 16081284 [PubMed - as supplied by publisher]
3:
Lowe LC, Guy M, Mansi JL, Peckitt C, Bliss J, Wilson RG, Colston KW.
Related Articles, Links


Plasma 25-hydroxy vitamin D concentrations, vitamin D receptor genotype and breast cancer risk in a UK Caucasian population.
Eur J Cancer. 2005 May;41(8):1164-9. Epub 2005 Apr 14.
PMID: 15911240 [PubMed - indexed for MEDLINE]
4:
Zinser GM, Tribble E, Valrance M, Urben CM, Knutson JC, Mazess RB, Strugnell SA, Welsh J.
Related Articles, Links


1,24(S)-dihydroxyvitamin D2, an endogenous vitamin D2 metabolite, inhibits growth of breast cancer cells and tumors.
Anticancer Res. 2005 Jan-Feb;25(1A):235-41.
PMID: 15816543 [PubMed - indexed for MEDLINE]
5:
DeMasters GA, Gupta MS, Jones KR, Cabot M, Wang H, Gennings C, Park M, Bratland A, Ree AH, Gewirtz DA.
Related Articles, Links


Potentiation of cell killing by fractionated radiation and suppression of proliferative recovery in MCF-7 breast tumor cells by the Vitamin D3 analog EB 1089.
J Steroid Biochem Mol Biol. 2004 Dec;92(5):365-74. Epub 2004 Dec 21.
PMID: 15698541 [PubMed - indexed for MEDLINE]
6:
Wietzke JA, Ward EC, Schneider J, Welsh J.
Related Articles, Links


Regulation of the human vitamin D3 receptor promoter in breast cancer cells is mediated through Sp1 sites.
Mol Cell Endocrinol. 2005 Jan 31;230(1-2):59-68.
PMID: 15664452 [PubMed - indexed for MEDLINE]
7:
Li F, Ling X, Huang H, Brattain L, Apontes P, Wu J, Binderup L, Brattain MG.
Related Articles, Links


Differential regulation of survivin expression and apoptosis by vitamin D3 compounds in two isogenic MCF-7 breast cancer cell sublines.
Oncogene. 2005 Feb 17;24(8):1385-95.
PMID: 15608672 [PubMed - indexed for MEDLINE]
8:
Banwell CM, O'Neill LP, Uskokovic MR, Campbell MJ.
Related Articles, Links


Targeting 1alpha,25-dihydroxyvitamin D3 antiproliferative insensitivity in breast cancer cells by co-treatment with histone deacetylation inhibitors.
J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):245-9.
PMID: 15225779 [PubMed - indexed for MEDLINE]
9:
Valrance ME, Welsh J.
Related Articles, Links


Breast cancer cell regulation by high-dose Vitamin D compounds in the absence of nuclear vitamin D receptor.
J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):221-5.
PMID: 15225775 [PubMed - indexed for MEDLINE]
10:
Demin S, Van Haver D, Vandewalle M, De Clercq PJ, Bouillon R, Verstuyf A.
Related Articles, Links


Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1alpha,25-dihydroxyvitamin D3: cis-perhydrindane CE-ring analogues.
Bioorg Med Chem Lett. 2004 Aug 2;14(15):3885-8.
PMID: 15225690 [PubMed - indexed for MEDLINE]
11:
McGaffin KR, Acktinson LE, Chrysogelos SA.
Related Articles, Links


Growth and EGFR regulation in breast cancer cells by vitamin D and retinoid compounds.
Breast Cancer Res Treat. 2004 Jul;86(1):55-73.
PMID: 15218361 [PubMed - indexed for MEDLINE]
12:
Kailajarvi ME, Salminen EK, Paija OM, Virtanent AM, Leino AE, Irjala KA.
Related Articles, Links


Serum bone markers in breast cancer patients during 5-fluorouracil, epirubicin and cyclophosphamide (FEC) therapy.
Anticancer Res. 2004 Mar-Apr;24(2C):1271-4.
PMID: 15154659 [PubMed - indexed for MEDLINE]
13:
Christensen GL, Jepsen JS, Fog CK, Christensen IJ, Lykkesfeldt AE.
Related Articles, Links


Sequential versus combined treatment of human breast cancer cells with antiestrogens and the vitamin D analogue EB1089 and evaluation of predictive markers for vitamin D treatment.
Breast Cancer Res Treat. 2004 May;85(1):53-63.
PMID: 15039597 [PubMed - indexed for MEDLINE]
14:
Punj V, Graves JM, Mehta RR.
Related Articles, Links


Effect of vitamin D analog (1alpha hydroxy D5) immunoconjugated to Her-2 antibody on breast cancer.
Int J Cancer. 2004 Mar 1;108(6):922-9.
PMID: 14712498 [PubMed - indexed for MEDLINE]
15:
Shen Q, Brown PH.
Related Articles, Links


Novel agents for the prevention of breast cancer: targeting transcription factors and signal transduction pathways.
J Mammary Gland Biol Neoplasia. 2003 Jan;8(1):45-73. Review.
PMID: 14587863 [PubMed - indexed for MEDLINE]
16:
Colston KW, Pirianov G, Bramm E, Hamberg KJ, Binderup L.
Related Articles, Links


Effects of Seocalcitol (EB1089) on nitrosomethyl urea-induced rat mammary tumors.
Breast Cancer Res Treat. 2003 Aug;80(3):303-11.
PMID: 14503802 [PubMed - indexed for MEDLINE]
17:
Chen YJ, Gao LJ, Murad I, Verstuyf A, Verlinden L, Verboven C, Bouillon R, Viterbo D, Milanesio M, Van Haver D, Vandewalle M, De Clercq PJ.
Related Articles, Links


Synthesis, biological activity, and conformational analysis of CD-ring modified trans-decalin 1 alpha,25-dihydroxyvitamin D analogs.
Org Biomol Chem. 2003 Jan 21;1(2):257-67.
PMID: 12929421 [PubMed - indexed for MEDLINE]
18:
Guyton KZ, Kensler TW, Posner GH.
Related Articles, Links


Vitamin D and vitamin D analogs as cancer chemopreventive agents.
Nutr Rev. 2003 Jul;61(7):227-38. Review.
PMID: 12918875 [PubMed - indexed for MEDLINE]
19:
Lowe L, Hansen CM, Senaratne S, Colston KW.
Related Articles, Links


Mechanisms implicated in the growth regulatory effects of vitamin D compounds in breast cancer cells.
Recent Results Cancer Res. 2003;164:99-110. Review.
PMID: 12908448 [PubMed - indexed for MEDLINE]
20:
Hussain EA, Mehta RR, Ray R, Das Gupta TK, Mehta RG.
Related Articles, Links


Efficacy and mechanism of action of 1alpha-hydroxy-24-ethyl-cholecalciferol (1alpha[OH]D5) in breast cancer prevention and therapy.
Recent Results Cancer Res. 2003;164:393-411. Review.
PMID: 12899538 [PubMed - indexed for MEDLINE]
Items 21 - 40 of 143 Previous

of 8
Next


21:
O'Kelly J, Koeffler HP.
Related Articles, Links


Vitamin D analogs and breast cancer.
Recent Results Cancer Res. 2003;164:333-48. Review.
PMID: 12899532 [PubMed - indexed for MEDLINE]
22:
Friedrich M, Rafi L, Mitschele T, Tilgen W, Schmidt W, Reichrath J.
Related Articles, Links


Analysis of the vitamin D system in cervical carcinomas, breast cancer and ovarian cancer.
Recent Results Cancer Res. 2003;164:239-46.
PMID: 12899526 [PubMed - indexed for MEDLINE]
23:
Banwell CM, Singh R, Stewart PM, Uskokovic MR, Campbell MJ.
Related Articles, Links


Antiproliferative signalling by 1,25(OH)2D3 in prostate and breast cancer is suppressed by a mechanism involving histone deacetylation.
Recent Results Cancer Res. 2003;164:83-98.
PMID: 12899515 [PubMed - indexed for MEDLINE]
24:
Bettoun DJ, Burris TP, Houck KA, Buck DW 2nd, Stayrook KR, Khalifa B, Lu J, Chin WW, Nagpal S.
Related Articles, Links


Retinoid X receptor is a nonsilent major contributor to vitamin D receptor-mediated transcriptional activation.
Mol Endocrinol. 2003 Nov;17(11):2320-8. Epub 2003 Jul 31.
PMID: 12893883 [PubMed - indexed for MEDLINE]
25:
Swamy N, Persons KS, Chen TC, Ray R.
Related Articles, Links


1alpha,25-Dihydroxyvitamin D3-3beta-(2)-bromoacetate, an affinity labeling derivative of 1alpha,25-dihydroxyvitamin D3 displays strong antiproliferative and cytotoxic behavior in prostate cancer cells.
J Cell Biochem. 2003 Aug 1;89(5):909-16.
PMID: 12874825 [PubMed - indexed for MEDLINE]
26:
Place AE, Suh N, Williams CR, Risingsong R, Honda T, Honda Y, Gribble GW, Leesnitzer LM, Stimmel JB, Willson TM, Rosen E, Sporn MB.
Related Articles, Links


The novel synthetic triterpenoid, CDDO-imidazolide, inhibits inflammatory response and tumor growth in vivo.
Clin Cancer Res. 2003 Jul;9(7):2798-806.
PMID: 12855660 [PubMed - indexed for MEDLINE]
27:
Welsh J, Wietzke JA, Zinser GM, Byrne B, Smith K, Narvaez CJ.
Related Articles, Links


Vitamin D-3 receptor as a target for breast cancer prevention.
J Nutr. 2003 Jul;133(7 Suppl):2425S-2433S. Review.
PMID: 12840219 [PubMed - indexed for MEDLINE]
28:
Flanagan L, Packman K, Juba B, O'Neill S, Tenniswood M, Welsh J.
Related Articles, Links


Efficacy of Vitamin D compounds to modulate estrogen receptor negative breast cancer growth and invasion.
J Steroid Biochem Mol Biol. 2003 Feb;84(2-3):181-92.
PMID: 12711002 [PubMed - indexed for MEDLINE]
29:
Wietzke JA, Welsh J.
Related Articles, Links


Phytoestrogen regulation of a Vitamin D3 receptor promoter and 1,25-dihydroxyvitamin D3 actions in human breast cancer cells.
J Steroid Biochem Mol Biol. 2003 Feb;84(2-3):149-57.
PMID: 12710998 [PubMed - indexed for MEDLINE]
30:
Polar MK, Gennings C, Park M, Gupta MS, Gewirtz DA.
Related Articles, Links


Effect of the vitamin D3 analog ILX 23-7553 on apoptosis and sensitivity to fractionated radiation in breast tumor cells and normal human fibroblasts.
Cancer Chemother Pharmacol. 2003 May;51(5):415-21. Epub 2003 Apr 11.
PMID: 12690516 [PubMed - indexed for MEDLINE]
31:
Zinser GM, McEleney K, Welsh J.
Related Articles, Links


Characterization of mammary tumor cell lines from wild type and vitamin D3 receptor knockout mice.
Mol Cell Endocrinol. 2003 Feb 28;200(1-2):67-80.
PMID: 12644300 [PubMed - indexed for MEDLINE]
32:
Mehta RG, Hussain EA, Mehta RR, Das Gupta TK.
Related Articles, Links


Chemoprevention of mammary carcinogenesis by 1alpha-hydroxyvitamin D5, a synthetic analog of Vitamin D.
Mutat Res. 2003 Feb-Mar;523-524:253-64.
PMID: 12628523 [PubMed - indexed for MEDLINE]
33:
Dolezalova H, Shankar G, Huang MC, Bikle DD, Goetzl EJ.
Related Articles, Links


Biochemical regulation of breast cancer cell expression of S1P2 (Edg-5) and S1P3 (Edg-3) G protein-coupled receptors for sphingosine 1-phosphate.
J Cell Biochem. 2003 Mar 1;88(4):732-43.
PMID: 12577307 [PubMed - indexed for MEDLINE]
34:
Osborne JE, Hutchinson PE.
Related Articles, Links


Vitamin D and systemic cancer: is this relevant to malignant melanoma?
Br J Dermatol. 2002 Aug;147(2):197-213. Review.
PMID: 12174089 [PubMed - indexed for MEDLINE]
35:
Chodynski M, Wietrzyk J, Marcinkowska E, Opolski A, Szelejewski W, Kutner A.
Related Articles, Links


Synthesis and antiproliferative activity of side-chain unsaturated and homologated analogs of 1,25-dihydroxyvitamin D(2). (24E)-(1S)-24-Dehydro-24a-homo-1,25-dihydroxyergocalciferol and congeners.
Steroids. 2002 Aug;67(9):789-98.
PMID: 12123791 [PubMed - indexed for MEDLINE]
36:
Mathiasen IS, Sergeev IN, Bastholm L, Elling F, Norman AW, Jaattela M.
Related Articles, Links


Calcium and calpain as key mediators of apoptosis-like death induced by vitamin D compounds in breast cancer cells.
J Biol Chem. 2002 Aug 23;277(34):30738-45. Epub 2002 Jun 18.
PMID: 12072431 [PubMed - indexed for MEDLINE]
37:
Colston KW, Hansen CM.
Related Articles, Links


Mechanisms implicated in the growth regulatory effects of vitamin D in breast cancer.
Endocr Relat Cancer. 2002 Mar;9(1):45-59. Review.
PMID: 11914182 [PubMed - indexed for MEDLINE]
38:
Tsai MS, Bogart DF, Li P, Mehmi I, Lupu R.
Related Articles, Links


Expression and regulation of Cyr61 in human breast cancer cell lines.
Oncogene. 2002 Jan 31;21(6):964-73.
PMID: 11840342 [PubMed - indexed for MEDLINE]
39:
Bortman P, Folgueira MA, Katayama ML, Snitcovsky IM, Brentani MM.
Related Articles, Links


Antiproliferative effects of 1,25-dihydroxyvitamin D3 on breast cells: a mini review.
Braz J Med Biol Res. 2002 Jan;35(1):1-9. Review.
PMID: 11743608 [PubMed - indexed for MEDLINE]
40:
Posner GH, Crawford KR, Peleg S, Welsh JE, Romu S, Gewirtz DA, Gupta MS, Dolan P, Kensler TW.
Related Articles, Links


A non-calcemic sulfone version of the vitamin D(3) analogue seocalcitol (EB 1089): chemical synthesis, biological evaluation and potency enhancement of the anticancer drug adriamycin.
Bioorg Med Chem. 2001 Sep;9(9):2365-71.
PMID: 11553477 [PubMed - indexed for MEDLINE
Items 41 - 60 of 143 Previous

of 8
Next


41:
Wang Q, Lee D, Sysounthone V, Chandraratna RAS, Christakos S, Korah R, Wieder R.
Related Articles, Links


1,25-dihydroxyvitamin D3 and retonic acid analogues induce differentiation in breast cancer cells with function- and cell-specific additive effects.
Breast Cancer Res Treat. 2001 May;67(2):157-68.
PMID: 11519864 [PubMed - indexed for MEDLINE]
42:
Yang L, Yang J, Venkateswarlu S, Ko T, Brattain MG.
Related Articles, Links


Autocrine TGFbeta signaling mediates vitamin D3 analog-induced growth inhibition in breast cells.
J Cell Physiol. 2001 Sep;188(3):383-93.
PMID: 11473365 [PubMed - indexed for MEDLINE]
43:
Akhter J, Lu Y, Finlay I, Pourgholami MH, Morris DL.
Related Articles, Links


1alpha,25-Dihydroxyvitamin D3 and its analogues, EB1089 and CB1093, profoundly inhibit the in vitro proliferation of the human hepatoblastoma cell line HepG2.
ANZ J Surg. 2001 Jul;71(7):414-7.
PMID: 11450917 [PubMed - indexed for MEDLINE]
44:
Hansen CM, Binderup L, Hamberg KJ, Carlberg C.
Related Articles, Links


Vitamin D and cancer: effects of 1,25(OH)2D3 and its analogs on growth control and tumorigenesis.
Front Biosci. 2001 Jul 1;6820-48. Review.
PMID: 11438443 [PubMed - indexed for MEDLINE]
45:
Chaudhry M, Sundaram S, Gennings C, Carter H, Gewirtz DA.
Related Articles, Links


The vitamin D3 analog, ILX-23-7553, enhances the response to adriamycin and irradiation in MCF-7 breast tumor cells.
Cancer Chemother Pharmacol. 2001 May;47(5):429-36.
PMID: 11391859 [PubMed - indexed for MEDLINE]
46:
Gewirtz DA, Sundaram S, Magnet KJ.
Related Articles, Links


Influence of topoisomerase II inhibitors and ionizing radiation on growth arrest and cell death pathways in the breast tumor cell.
Cell Biochem Biophys. 2000;33(1):19-31. Review.
PMID: 11322510 [PubMed - indexed for MEDLINE]
47:
Verlinden L, Verstuyf A, Quack M, Van Camp M, Van Etten E, De Clercq P, Vandewalle M, Carlberg C, Bouillon R.
Related Articles, Links


Interaction of two novel 14-epivitamin D3 analogs with vitamin D3 receptor-retinoid X receptor heterodimers on vitamin D3 responsive elements.
J Bone Miner Res. 2001 Apr;16(4):625-38.
PMID: 11315990 [PubMed - indexed for MEDLINE]
48:
Hisatake J, O'Kelly J, Uskokovic MR, Tomoyasu S, Koeffler HP.
Related Articles, Links


Novel vitamin D(3) analog, 21-(3-methyl-3-hydroxy-butyl)-19-nor D(3), that modulates cell growth, differentiation, apoptosis, cell cycle, and induction of PTEN in leukemic cells.
Blood. 2001 Apr 15;97(8):2427-33.
PMID: 11290607 [PubMed - indexed for MEDLINE]
49:
Akutsu N, Bastien Y, Lin R, Mader S, White JH.
Related Articles, Links


Amphiregulin is a vitamin D3 target gene in squamous cell and breast carcinoma.
Biochem Biophys Res Commun. 2001 Mar 9;281(4):1051-6.
PMID: 11237771 [PubMed - indexed for MEDLINE]
50:
Larsen SS, Heiberg I, Lykkesfeldt AE.
Related Articles, Links


Anti-oestrogen resistant human breast cancer cell lines are more sensitive towards treatment with the vitamin D analogue EB1089 than parent MCF-7 cells.
Br J Cancer. 2001 Mar 2;84(5):686-90.
PMID: 11237391 [PubMed - indexed for MEDLINE]
51:
Rashid SF, Mountford JC, Gombart AF, Campbell MJ.
Related Articles, Links


1alpha,25-dihydroxyvitamin D(3) displays divergent growth effects in both normal and malignant cells.
Steroids. 2001 Mar-May;66(3-5):433-40.
PMID: 11179752 [PubMed - indexed for MEDLINE]
52:
Pirianov G, Colston KW.
Related Articles, Links


Interaction of vitamin D analogs with signaling pathways leading to active cell death in breast cancer cells.
Steroids. 2001 Mar-May;66(3-5):309-18.
PMID: 11179739 [PubMed - indexed for MEDLINE]
53:
Pirianov G, Colston KW.
Related Articles, Links


Interactions of vitamin D analogue CB1093, TNFalpha and ceramide on breast cancer cell apoptosis.
Mol Cell Endocrinol. 2001 Feb 14;172(1-2):69-78.
PMID: 11165041 [PubMed - indexed for MEDLINE]
54:
Sundaram S, Chaudhry M, Reardon D, Gupta M, Gewirtz DA.
Related Articles, Links


The vitamin D3 analog EB 1089 enhances the antiproliferative and apoptotic effects of adriamycin in MCF-7 breast tumor cells.
Breast Cancer Res Treat. 2000 Sep;63(1):1-10.
PMID: 11079153 [PubMed - indexed for MEDLINE]
55:
[No authors listed]
Related Articles, Links


Drugs for prevention and treatment of postmenopausal osteoporosis.
Med Lett Drugs Ther. 2000 Oct 16;42(1090):97-100. No abstract available.
PMID: 11035622 [PubMed - indexed for MEDLINE]
56:
El Abdaimi K, Dion N, Papavasiliou V, Cardinal PE, Binderup L, Goltzman D, Ste-Marie LG, Kremer R.
Related Articles, Links


The vitamin D analogue EB 1089 prevents skeletal metastasis and prolongs survival time in nude mice transplanted with human breast cancer cells.
Cancer Res. 2000 Aug 15;60(16):4412-8.
PMID: 10969786 [PubMed - indexed for MEDLINE]
57:
Swami S, Krishnan AV, Feldman D.
Related Articles, Links


1alpha,25-Dihydroxyvitamin D3 down-regulates estrogen receptor abundance and suppresses estrogen actions in MCF-7 human breast cancer cells.
Clin Cancer Res. 2000 Aug;6(8):3371-9.
PMID: 10955825 [PubMed - indexed for MEDLINE]
58:
Byrne IM, Flanagan L, Tenniswood MP, Welsh J.
Related Articles, Links


Identification of a hormone-responsive promoter immediately upstream of exon 1c in the human vitamin D receptor gene.
Endocrinology. 2000 Aug;141(8):2829-36.
PMID: 10919269 [PubMed - indexed for MEDLINE]
59:
Norman AW, Manchand PS, Uskokovic MR, Okamura WH, Takeuchi JA, Bishop JE, Hisatake JI, Koeffler HP, Peleg S.
Related Articles, Links


Characterization of a novel analogue of 1alpha,25(OH)(2)-vitamin D(3) with two side chains: interaction with its nuclear receptor and cellular actions.
J Med Chem. 2000 Jul 13;43(14):2719-30.
PMID: 10893309 [PubMed - indexed for MEDLINE]
60:
Mehta RR, Bratescu L, Graves JM, Green A, Mehta RG.
Related Articles, Links


Differentiation of human breast carcinoma cells by a novel vitamin D analog: 1alpha-hydroxyvitamin D5.
Int J Oncol. 2000 Jan;16(1):65-73.
PMID: 10601550 [PubMed - indexed for MEDLINE]

Vitamin D and pregnancy:

1alpha,25-dihydroxy-vitamin-D3 as new immunotherapy in treatment of recurrent spontaneous abortion.
Med Hypotheses. 2004;63(2):250-3.
PMID: 15236784 [PubMed - indexed for MEDLINE]

Vitamin D deficiency during pregnancy: a risk factor not only for fetal growth and bone metabolism but also for correct development of the fetal immune system?
Am J Clin Nutr. 2005 May;81(5):1177; author reply 1177-8. No abstract available.

PMID: 15883446 [PubMed - indexed for MEDLINE]
Vitamin D for the prevention of preeclampsia? A hypothesis.
Nutr Rev. 2005 Jul;63(7):225-32. Review.
PMID: 16121476 [PubMed - indexed for MEDLINE]

Benefits and requirements of vitamin D for optimal health: a review.
Altern Med Rev. 2005 Jun;10(2):94-111. Review.
PMID: 15989379 [PubMed - indexed for MEDLINE]

Maternal and seasonal predictors of change in calcaneal quantitative ultrasound during pregnancy.
J Clin Endocrinol Metab. 2005 Sep;90(9):5182-7. Epub 2005 Jun 28.
PMID: 15985491 [PubMed - indexed for MEDLINE]

Bone status during adolescence, pregnancy and lactation.
Curr Opin Obstet Gynecol. 2005 Aug;17(4):435-9.
PMID: 15976553 [PubMed - in process]

Review of vitamin D deficiency during pregnancy: who is affected?
Int J Circumpolar Health. 2005 Apr;64(2):112-20. Review.
PMID: 15945281 [PubMed - indexed for MEDLINE]

Transient prenatal vitamin D deficiency is associated with subtle alterations in learning and memory functions in adult rats.
Behav Brain Res. 2005 Jun 20;161(2):306-12.
PMID: 15922058 [PubMed - indexed for MEDLINE]

[Seizures in foreign newborns due to maternal vitamin-D deficiency]
Ned Tijdschr Geneeskd. 2005 Apr 23;149(17):958-9. Dutch. No abstract available.
PMID: 15884412 [PubMed - indexed for MEDLINE]

Multiple micronutrients in pregnancy and lactation: an overview.
Am J Clin Nutr. 2005 May;81(5):1206S-1212S. Review.
PMID: 15883453 [PubMed - indexed for MEDLINE]

High prevalence of vitamin D deficiency among pregnant women and their newborns in northern India.
Am J Clin Nutr. 2005 May;81(5):1060-4.
PMID: 15883429 [PubMed - indexed for MEDLINE]

Hypovitaminosis D, insulin resistance and hypertension in pregnancy.
Eur J Clin Nutr. 2005 Jun;59(6):805-6. No abstract available.
PMID: 15841094 [PubMed - indexed for MEDLINE]

Neonatal hyperparathyroidism due to maternal hypoparathyroidism and vitamin D deficiency: a cause of multiple bone fractures.
Clin Pediatr (Phila). 2005 Apr;44(3):267-9. No abstract available.
PMID: 15821853 [PubMed - indexed for MEDLINE]

[Calcium homeostasis and bone turnover in pregnancy and breast feeding]
Ugeskr Laeger. 2005 Feb 28;167(9):1005-9. Review. Danish. No abstract available.
PMID: 15803993 [PubMed - indexed for MEDLINE]

[The effect of vitamin-mineral supplementation on vitamins D, A (beta-carotene) and E concentration in blood of matched maternal-cord pairs]
Przegl Lek. 2004;61(7):755-9. Polish.
PMID: 15792015 [PubMed - indexed for MEDLINE]

[Calcium and vitamin D metabolism during pregnancy and lactation]
Clin Calcium. 2003 Jul;13(7):892-6. Japanese.
PMID: 15775163 [PubMed]

Developmental Vitamin D3 deficiency alters the adult rat brain.
Brain Res Bull. 2005 Mar 15;65(2):141-8.
PMID: 15763180 [PubMed - indexed for MEDLINE]

The vitamin D receptor is not required for fetal mineral homeostasis or for the regulation of placental calcium transfer in mice.
Am J Physiol Endocrinol Metab. 2005 Jul;289(1):E133-44. Epub 2005 Mar 1.
PMID: 15741244 [PubMed - indexed for MEDLINE]

[Seizures in foreign newborns due to maternal vitamin-D deficiency]
Ned Tijdschr Geneeskd. 2005 Jan 29;149(5):257-60. Dutch.
PMID: 15719838 [PubMed - indexed for MEDLINE]

Zeni SN, Ortela Soler CR, Lazzari A, Lopez L, Suarez M, Di Gregorio S, Somoza JI, de Portela ML.
Interrelationship between bone turnover markers and dietary calcium intake in pregnant women: a longitudinal study.
Bone. 2003 Oct;33(4):606-13.
PMID: 14555265 [PubMed - indexed for MEDLINE]

Quinn JM, Fujikawa Y, McGee JO, Athanasou NA.
Rodent osteoblast-like cells support osteoclastic differentiation of human cord blood monocytes in the presence of M-CSF and 1,25 dihydroxyvitamin D3.
Int J Biochem Cell Biol. 1997 Jan;29(1):173-9.
PMID: 9076952 [PubMed - indexed for MEDLINE]

Caplan RH, Wickus GG.
Reduced calcitriol requirements for treating hypoparathyroidism during lactation. A case report.
J Reprod Med. 1993 Nov;38(11):914-8.
PMID: 8277494 [PubMed - indexed for MEDLINE]

Pittard WB 3rd, Geddes KM, Hulsey TC, Hollis BW.
How much vitamin D for neonates?
Am J Dis Child. 1991 Oct;145(10):1147-9.
PMID: 1928007 [PubMed - indexed for MEDLINE]

Caplan RH, Beguin EA.
Hypercalcemia in a calcitriol-treated hypoparathyroid woman during lactation.
Obstet Gynecol. 1990 Sep;76(3 Pt 2):485-9.
PMID: 2381632 [PubMed - indexed for MEDLINE]

Wilson SG, Retallack RW, Kent JC, Worth GK, Gutteridge DH.
Serum free 1,25-dihydroxyvitamin D and the free 1,25-dihydroxyvitamin D index during a longitudinal study of human pregnancy and lactation.
Clin Endocrinol (Oxf). 1990 May;32(5):613-22.
PMID: 2364565 [PubMed - indexed for MEDLINE]

Newman V, Lyon RB, Anderson PO.
Evaluation of prenatal vitamin-mineral supplements.
Clin Pharm. 1987 Oct;6(10):770-7.
PMID: 3505840 [PubMed - indexed for MEDLINE]

Lamberg-Allardt C, Larjosto M, Schultz E.
25-Hydroxyvitamin D concentrations in maternal and cord blood at delivery and in maternal blood during lactation in Finland.
Hum Nutr Clin Nutr. 1984 Jul;38(4):261-8.
PMID: 6088438 [PubMed - indexed for MEDLINE]

Whitehead M, Lane G, Young O, Campbell S, Abeyasekera G, Hillyard CJ, MacIntyre I, Phang KG, Stevenson JC.
Interrelations of calcium-regulating hormones during normal pregnancy.
Br Med J (Clin Res Ed). 1981 Jul 4;283(6283):10-2.
PMID: 6788241 [PubMed - indexed for MEDLINE]

I started the vitamin D supplements today. The switch off of daylight savings got me motivated. I ended up taking 1200 IU total.

Let me know if you notice any difference after 3-7 days, would you?

I'm still on the D since last fall/winter. I cut back this summer to 800-1000 IU most days. I'm currently 1400-1600 IU and am trying to sneak in an extra 200 IU here and there, but I still tend to get headaches if I'm not careful and they really wipe me out so I have to back off when they hit. Other than that, I'm doing good on it and after about 5 weeks at my increased level, my weight has dropped back down to 148#(it had been hanging around 152-154 for most of the summer). I think part of it is that I seem to be able to lose more easily in the winter as the humidity really zaps me in the summer with me being a runner... And I also cut out the splenda in my coffee that I had developed a bad habit of this summer. So, probably a combination of all of the above, but I do think the D plays a big part in helping.

Cindi
What form of D are you taking? Are you taking the gels?

Many are having reactions to the D in gels: it seems to be a reaction to the soy oil and not the D.

Vitamin D and Depression
J Nutr Health Aging. 1999;3(1):5-7. Related Articles, Links

Vitamin D vs broad spectrum phototherapy in the treatment of seasonal affective disorder.
Gloth FM 3rd, Alam W, Hollis B.
http://www.ncbi.nlm.nih.gov/entrez/...earch&DB=pubmed


MAJOR DEPRESSION AND VITAMIN D
Corresponding author:
John Jacob Cannell, MD
http://www.cholecalciferol-council...._depression.htm


J Am Coll Nutr. 2000 Apr;19(2):220-7. Related Articles, Links


Micronutrients and the premenstrual syndrome: the case for calcium.
Thys-Jacobs S.
http://www.ncbi.nlm.nih.gov/entrez/...earch&DB=pubmed


The Magnesium Web Site
MAGNESIUM ONLINE LIBRARY
http://www.mgwater.com/clmd.shtml


Int J Psychiatry Med. 1989;19(1):57-63. Related Articles, Links

Depression and magnesium deficiency.

Rasmussen HH, Mortensen PB, Jensen IW.
http://www.ncbi.nlm.nih.gov/entrez/...earch&DB=pubmed


Neuropharmacology. 2004 Dec;47(8):1189-97. Related Articles, Links


Magnesium-deficient diet alters depression- and anxiety-related behavior in mice--influence of desipramine and Hypericum perforatum extract.
Singewald N, Sinner C, Hetzenauer A, Sartori SB, Murck H.
http://www.ncbi.nlm.nih.gov/entrez/...earch&DB=pubmed


Alcohol Clin Exp Res. 2004 Nov;28(11):1702-9. Related Articles, Links


Magnesium treatment of primary alcohol-dependent patients during subacute withdrawal: an open pilot study with polysomnography.
Hornyak M, Haas P, Veit J, Gann H, Riemann D.
http://www.ncbi.nlm.nih.gov/entrez/...457&query_hl=26


Intern Med. 2004 May;43(5):410-4. Related Articles, Links


Depressive state and paresthesia dramatically improved by intravenous MgSO4 in Gitelman's syndrome.
Enya M, Kanoh Y, Mune T, Ishizawa M, Sarui H, Yamamoto M, Takeda N, Yasuda K, Yasujima M, Tsutaya S, Takeda J.
http://www.ncbi.nlm.nih.gov/entrez/...earch&DB=pubmed


Magnes Res. 2002 Mar;15(1-2):49-66. Related Articles, Links


Biorhythms and possible central regulation of magnesium status, phototherapy, darkness therapy and chronopathological forms of magnesium depletion.
Durlach J, Pages N, Bac P, Bara M, Guiet-Bara A.
http://www.ncbi.nlm.nih.gov/entrez/...earch&DB=pubmed


Med Hypotheses. 2002 Jan;58(1):47-60. Related Articles, Links


The central role of magnesium deficiency in Tourette's syndrome: causal relationships between magnesium deficiency, altered biochemical pathways and symptoms relating to Tourette's syndrome and several reported comorbid conditions.
Grimaldi BL.
http://www.ncbi.nlm.nih.gov/entrez/...earch&DB=pubmed

This is the wrong time of the year, for a northern hemisphere person, to post this but if anyone is worried about gettin skin cancer from sunning to get vitamin D, here is something to reduce the odds.

http://www.forbes.com/finance/feeds...afx2320586.html

Australian research shows aspirin may prevent skin cancer

SYDNEY (AFX) - The common painkiller aspirin, already found to be effective in reducing the risk of heart disease, may also help lower the incidence of skin cancer, Australian researchers said.

According to a study undertaken by the Queensland Institute of Medical Research, regularly taking non-steroidal anti-inflammatory drugs such as aspirin could offer increased protection against skin cancer and sunspots.

'We found that people who regularly used aspirin and other NSAIDs (non-steroidal anti-inflammatory drugs) had significantly lower risks of developing skin cancer than people who did not use them,' researcher David Whiteman said.

'Moreover, we found that among people who had never had skin cancer, those who regularly used aspirin had significantly lower numbers of sunspots.'

Whiteman said that aspirin-type drugs shut down an enzyme known as cyclo-oxygenase (COX) which allows some types of skin cancer to develop.

'Aspirin blocks the COX enzyme and it just so happens that these enzymes are involved in inflammation... and these enzymes are also used by cancer cells to stimulate blood cells,' he told Agence France-Presse.

That's very interesting news Dodger!!! That means you can get out and make your vitamin D, take your vitamin D to protect against 32 kinds of cancer and take an aspirin to protect against the one not covered!!!

Hi
Interesting thread. Guess I'll go get some sun and take some aspirin.
LizzyLC

Relationship Between Serum Parathyroid Hormone Levels, Vitamin D Sufficiency, and Calcium Intake

Laufey Steingrimsdottir, PhD; Orvar Gunnarsson, MD; Olafur S. Indridason, MD, MHS; Leifur Franzson, MSc, Pharm; Gunnar Sigurdsson, MD, PhD

JAMA. 2005;294:2336-2341.

Context Adequate vitamin D status for optimum bone health has received increased recognition in recent years; however, the ideal intake is not known. Serum 25-hydroxyvitamin D is the generally accepted indicator of vitamin D status, but no universal reference level has been reached.

Objective To investigate the relative importance of high calcium intake and serum 25-hydroxyvitamin D for calcium homeostasis, as determined by serum intact parathyroid hormone (PTH).

Design, Setting, and Participants Cross-sectional study of 2310 healthy Icelandic adults who were divided equally into 3 age groups (30-45 years, 50-65 years, or 70-85 years) and recruited from February 2001 to January 2003. They were administered a semi-quantitative food frequency questionnaire, which assessed vitamin D and calcium intake. Participants were further divided into groups according to calcium intake (<800 mg/d, 800-1200 mg/d, and >1200 mg/d) and serum 25-hydroxyvitamin D level (<10 ng/mL, 10-18 ng/mL, and >18 ng/mL).

Main Outcome Measure Serum intact PTH as determined by calcium intake and vitamin D.

Results A total of 944 healthy participants completed all parts of the study. After adjusting for relevant factors, serum PTH was lowest in the group with a serum 25-hydroxyvitamin D level of more than 18 ng/mL but highest in the group with a serum 25-hydroxyvitamin D level of less than 10 ng/mL. At the low serum 25-hydroxyvitamin D level (<10 ng/mL), calcium intake of less than 800 mg/d vs more than 1200 mg/d was significantly associated with higher serum PTH (P = .04); and at a calcium intake of more than 1200 mg/d, there was a significant difference between the lowest and highest vitamin D groups (P = .04).

Conclusions As long as vitamin D status is ensured, calcium intake levels of more than 800 mg/d may be unnecessary for maintaining calcium metabolism. Vitamin D supplements are necessary for adequate vitamin D status in northern climates.

Author Affiliations: Public Health Institute of Iceland (Dr Steingrimsdottir); University of Iceland (Drs Gunnarsson and Sigurdsson); and Department of Medicine (Drs Indridason and Sigurdsson) and Clinical Chemistry (Dr Franzson), Landspitali-University Hospital, Reykjavik, Iceland.

That's great!! It means I can reduce my calcium intake.

Mike, I find this stuff so fascinating. I can't get enough of it. And all I've found/heard is positive!!

How are you doing on the D now?

So how much should women be taking? I can't possibly wade through all those studies although they seem fascinating. I live in AZ so we have a lot of sun, year round - maybe that means I wouldn't need as much. On the other hand, I'm not in the sun this time of year - too cold to swim. Confusing. Even though we are in AZ you can still suffer from SAD - gets dark early - not anything like up north though - I'm from the NE so I can dig it.