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I've never used it but have been reading about it for quite some time. Some report their workouts to be more intense while taking creatine while others have had problems with it. Of course you have to follow the directions carefully which I find many people having a hard time to do with most things. This is the best article that I've read on the subject because he's not only a good researcher, he's used it himself. As for the fibro side of your question I can't offer you anything. Hope this helps.