I just discovered proteolytic enzymes ~4-5 months ago and can't say enough good things about them... and I've tried everything!! both rx and supplements... very discouraged... I tried Wobenzym on a whim and it's been miraculous for arthritis pain and stiffness... I am currently using a formula called Vascuzyme, which I like because it's odorless.. Either brand does the job, though... Highly recommend, and let us know how it works for you... Also, I take high doses.. 6 - 8 pills, 2x per day... Read the reviews on amazon, there are others who do this, but try the recommended doses and go slow at first