Active Low-Carber Forums
Atkins diet and low carb discussion provided free for information only, not as medical advice.
Home Plans Tips Recipes Tools Stories Studies Products
Active Low-Carber Forums
A sugar-free zone

Welcome to the Active Low-Carber Forums.
Support for Atkins diet, Protein Power, Neanderthin (Paleo Diet), CAD/CALP, Dr. Bernstein Diabetes Solution and any other healthy low-carb diet or plan, all are welcome in our lowcarb community. Forget starvation and fad diets -- join the healthy eating crowd! You may register by clicking here, it's free!

Go Back   Active Low-Carber Forums > Main Low-Carb Diets Forums & Support > Low-Carb Studies & Research / Media Watch > LC Research/Media
User Name
FAQ Members Calendar Mark Forums Read Search Gallery My P.L.A.N. Survey

Thread Tools Display Modes
  #1   ^
Old Fri, Jan-22-21, 09:45
JEY100's Avatar
JEY100 JEY100 is offline
Posts: 12,162
Plan: P:E/DDF
Stats: 225/150/169 Female 5' 9"
Progress: 134%
Location: NC
Default Central adiposity was positively associated with pre- and postmenopausal breast cance

Central adiposity and subsequent risk of breast cancer by menopause status

Increased body mass index (BMI) is associated with higher postmenopausal breast cancer risk and lower premenopausal breast cancer risk. Less is known about the central adiposity-breast cancer risk association, particularly for tumor subtypes.
We used prospective waist (WC) and hip circumference (HC) measures in the Nurses’ Health Studies. We examined associations of WC, HC and waist-to-hip ratio (WHR) with breast cancer independent of BMI, by menopausal status. Cox proportional hazards models estimated the hazard ratio (HR) and 95% confidence intervals (CI) adjusting for breast cancer risk factors, with and without BMI.
Adjusting for BMI, WC, and HC were not associated and WHR was positively associated with premenopausal breast cancer risk (WHR, quintile 5 vs. 1: HRQ5vQ1, BMI-adjusted=1.27, 95%CI = 1.04–1.54, p-trend = 0.01); particularly for, estrogen receptor-negative (ER-)/ progesterone receptor-negative (PR-) and basal-like breast cancers. Premenopausal WC, HC, and WHR were not associated with postmenopausal breast cancer risk, with or without BMI adjustment. Postmenopausal WC, HC, and WHR were each positively associated with postmenopausal breast cancer (eg, WC HRQ5vsQ1=1.59, 95%CI = 1.36–1.86); after adjustment for BMI, only WC remained statistically significant (HRQ5vsQ1, BMI-adjusted=1.38, 95%CI = 1.15–1.64, p-trend = 0.002). In postmenopausal women, associations were stronger among never users of hormone therapy and for ER+/PR+ breast cancers.
Central adiposity was positively associated with pre- and postmenopausal breast cancers independent of BMI. This suggests that mechanisms other than estrogen may also play a role in the relationship between central adiposity and breast cancer. Maintaining a healthy waist circumference may decrease pre- and postmenopausal breast cancer risk.
Reply With Quote
Sponsored Links

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off

All times are GMT -6. The time now is 23:19.

Copyright © 2000-2022 Active Low-Carber Forums @
Powered by: vBulletin, Copyright ©2000 - 2022, Jelsoft Enterprises Ltd.