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  #1   ^
Old Tue, Oct-23-18, 10:04
teaser's Avatar
teaser teaser is offline
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Plan: mostly milkfat
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Default Endurance exercise training has beneficial effects on gut microbiota composition

https://www.sciencedaily.com/releas...81015105451.htm

Quote:
According to recent research, endurance exercise training beneficially modifies gut microbiota composition. After six weeks of training, potentially inflammation causing microbes (Proteobacteria) decreased and microbes that are linked to enhanced metabolism (Akkermansia) increased.

Even though there was no significant drop in the weight of the subjects, exercise had other beneficial health effects, says Academy of Finland research fellow Satu Pekkala from the Faculty of Sport and Health Sciences of the University of Jyväskylä.

"We found that phospholipids and cholesterol in VLDL particles decreased in response to exercise. These changes are beneficial for cardiometabolic health because VLDL transports lipids from the liver to peripheral tissues, converts into 'bad' LDL cholesterol in the circulation, and thus has detrimental cardiovascular effects."

Exercise training also decreased Vascular adhesion protein-1 activity, which can have beneficial anti-inflammatory effects especially on vasculature, though the underlying mechanisms could not be determined in this study.

Whether Akkermansia mediates the health benefits of exercise is under further investigation

A few other cross-sectional studies have shown that microbes belonging to the Akkermansia genus are more abundant among physically active subjects than they are among inactive ones. Akkermansia has been a target of intense research recently, and some researchers believe that it may prevent obesity and diabetes.

"However, more studies are needed to prove that Akkermansia might mediate some of the health benefits of exercise," Pekkala says.

In addition to the composition of the gut microbiota, changes in their genes, that is, in their functionality, were studied.

"The abundance of the functional genes did not change much, which was perhaps to be expected because the diet did not change during training," Pekkala points out. "If the training period had been longer, greater effects probably would have been seen."

The research team made an exercise intervention for overweight women, which was completed by 17 subjects. Over a six-week period, previously sedentary women participated in three training sessions per week with a bicycle ergometer. The training intensity was controlled with heart rate. During the study, other lifestyle factors, including diet, were not changed in order to ensure that the effects of exercise could be observed. The research was carried out as a collaboration between the Faculty of Sport and Health Sciences of the University of Jyväskylä, University of Turku and the Spanish nonprofit research and healthcare organization FISABIO.



The connection to low carb is fairly nerdy here. Akkermansia bacteria, at least the beneficial ones I've read about, are mucin-munchers. Mucin is a mucousy barrier that protects the gut, the Akkermansia send out signals that spur the intestine to produce more mucin, improving the barrier. Low carb critics have accused low carb as being bad for the gut, because it increased these bacteria in some n=1 cases who sent their stools to be judged, with the assumption that mucin-munching must be bad. There are some studies in mice and seizures with a ketogenic diet, showing benefits of an increase in these particular bacteria versus seizures, a fecal transplant actually works versus seizures in non-ketogenically fed mice.
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  #2   ^
Old Tue, Oct-23-18, 10:28
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GRB5111 GRB5111 is offline
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Valuable information. In addition to a favorable microbe balance, VLDL decreasing, and anti-inflammatory benefits, I would assume a corresponding increase in mitochondria and mitochondrial health would be present as well. As mitochondria increase, can we assume this helps tip the balance from sedentary to active in that individuals start to feel the urge to pursue physical activity on a more frequent basis, thus creating a positive feedback system effect?
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  #3   ^
Old Wed, Oct-24-18, 07:48
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bkloots bkloots is offline
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Does anyone need this much information to know: Exercise is Good.

I do like knowing that mucin-munchers are not bad, however.

Thanks for staying on top of the revelations of science.
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