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  #1   ^
Old Sat, Nov-18-06, 14:54
Whoa182's Avatar
Whoa182 Whoa182 is offline
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Plan: CRON / Zone
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Default Low Cholesterol Lowers Risk for Aggressive Prostate Cancer

Low Cholesterol Lowers Risk for Aggressive Prostate Cancer
http://www.forbes.com/forbeslife/he...cout536073.html

Low Cholesterol Lowers Risk for Aggressive Prostate Cancer
11.16.06, 12:00 AM ET

THURSDAY, Nov. 16 (HealthDay News) -- Men with low blood cholesterol levels are at lowered risk of high-grade and possibly advanced prostate cancer, researchers report.

Lower cholesterol does not lower a man's overall risk for prostrate cancer, however, concludes a U.S. study presented this week at the annual meeting of the American Association for Cancer Research, in Boston.

Previously, the researchers found that men who used cholesterol-lowering statin drugs were about 50 percent less likely to have advanced prostate cancer. It's known that cholesterol plays a role in a number of factors that can influence the start of cancer.

In this new study, researchers at Johns Hopkins University and elsewhere investigated whether a low plasma cholesterol level is associated with lower prostate cancer risk overall. They also examined the link between plasma cholesterol level and stage and grade of prostate cancer.

The study included 698 men with prostate cancer and 698 prostate cancer-free men in a control group. The team measured each man's plasma concentration of total cholesterol.

"Men with low plasma cholesterol had a lower risk of high-grade and possibly advanced prostate cancer, but not prostate cancer overall," the researchers wrote.

More information

The American Cancer Society has more about prostate cancer.
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  #2   ^
Old Sat, Nov-18-06, 16:56
Dodger's Avatar
Dodger Dodger is offline
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Plan: Paleoish/Keto
Stats: 225/167/175 Male 71.5 inches
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I have a feeling that the low cholesterol was more low triglycerides.
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  #3   ^
Old Sat, Nov-18-06, 23:02
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eddiemcm eddiemcm is offline
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Plan: south beach
Stats: 225/170/165 Male 70 inches
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About 600 mg of beta sitosterol per day will
protect a male from prostrate cancer and also
lower the amount of dietary cholesterol that
winds up in blood.Many studies validate this.
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  #4   ^
Old Mon, Nov-20-06, 18:31
durhamgirl durhamgirl is offline
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quote: Previously, the researchers found that men who used cholesterol-lowering statin drugs were about 50 percent less likely to have advanced prostate cancer. It's known that cholesterol plays a role in a number of factors that can influence the start of cancer.

Statins lower testosterone too, right?
So perhaps this has some effect. & in the absence of statins, lower testosterone and cholesterol may be related. I

don't know whether they looked at this in the study... & too lazy to go look it up right now. (plus, I have to go watch "Prison Break")

but P.S. Not every man WANTS lower testosterone. : ) & not every woman wants her man to have lower testosterone either.

: )
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  #5   ^
Old Sun, Nov-26-06, 06:54
Lilly5 Lilly5 is offline
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Default Low Cholesterol Lowers Risk for Aggressive Prostate Cancer

Good news for men.
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  #6   ^
Old Sun, Nov-26-06, 07:26
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eddiemcm eddiemcm is offline
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Plan: south beach
Stats: 225/170/165 Male 70 inches
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Progress: 92%
Location: Houston,Texas
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"I have a feeling that the low cholesterol was more low triglycerides."
Triglycerides has a very small effect on total
cholesterol:
TC=HDL+LDL+(TG/5)
That's the equation that blood labs use.
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  #7   ^
Old Sun, Nov-26-06, 07:37
Lisa N's Avatar
Lisa N Lisa N is offline
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Plan: Bernstein Diabetes Soluti
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Ummm...can I point out the obvious that how advanced a cancer is upon discovery depends entirely on how early it's caught and that your cholesterol levels have absolutely nothing to do with that?
What this study might show is that men with low cholesterol see their doctors more frequently and, therefore, catch their cancers in an earlier stage than a man who only sees the doc once every few years on average.
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  #8   ^
Old Sun, Nov-26-06, 11:32
Zuleikaa Zuleikaa is offline
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There are really too many variables to isolate. How about their vitamin D status? And the time of year they were diagnosed? Many studies have show a positive correlation between vitamin D status, prostate cancer incidence, agressiveness, and survival rates.
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  #9   ^
Old Tue, Dec-26-06, 19:45
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LarryAJ LarryAJ is offline
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Plan: PP/PPLP
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A-hah!! In the thread Is Your Cholesterol too Low? there is the following;
Quote:
Originally Posted by kebaldwin
<clip>

Likewise, you need your cholesterol. It is a central part of some very important metabolic pathways. In fact, it is probably the most important hormone precursor in your body. You make all sex steroids from cholesterol.
<clip>


It is well known that Prostate cancer seems to feed on testosterone. And an aggressive cancer is a fast growing one. Moreover, by putting a man with Prostate cancer on triple hormone blockade (stops all testosterone production) halts the growth and spread of the cancer. Is it any surprise, then, that low cholesterol, which would lower the testosterone production, will slow Prostate cancer making it less aggressive??

BUT!! having NO testosterone is NOT good!! Just ask a man that is on triple hormone blockade. Bone density loss is a common side effect, one that can be very serious! Men that have bone fractures from hormone therapy have a 50% survival rate five years after the fracture. And that is just ONE of several of the side affects.
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  #10   ^
Old Tue, Dec-26-06, 19:58
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Whoa182 Whoa182 is offline
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Plan: CRON / Zone
Stats: 118/110/110 Male 5ft 7"
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Okinawans have almost half the number of broken hips as americans, and are less likely to die from them when they do have them. They also have cholesterol of around 150mg/dl... and quite a few are vitamin D deficient. They also have BMI's of around 18-22 mind you, far more leaner, smaller bones, yet less fractures.

See the link to look at Okies vs americans and the hormone DHEA. It shows a lower amount at first, but it has a much slower decline. The same is quite true for Testosterone in okinawans... yes it is initially lower, but they have a slower decline again. I'm not even sure that having really high level of these hormones is even a good thing!

DHEA- http://img.photobucket.com/albums/v...82/000_1922.jpg

http://okinawaprogram.com/study.html

See that graph... did having a higher level of DHEA early on in life, and middle age give americans better future prospects? NOT QUITE

Americans spend around 10 ~ years with disability, okinwans around 1-2 years at the end of life. Americans having higher hormones like T, DHEA throughout most of their life lead to longer or healthier lives? NO not at all.

Last edited by Whoa182 : Tue, Dec-26-06 at 20:24.
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  #11   ^
Old Tue, Dec-26-06, 20:38
Gostrydr Gostrydr is offline
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Larry Aj wrote:
It is well known that Prostate cancer seems to feed on testosterone.

Not true. DHT, testoterones evil twin is the culprit. Proscar is a DHT inhibitor. Also there is alot of research right now that is leaning toward estrogen as the main factor toward BHP. But I have seen papers on studies of using estrogen for prostrate cancer..oh vey

Having low tesosterone(as I do) is one of the most unhealthiest thing for men to have(women as well). Testosterone literally feeds every cell we have including brain cels.

http://www.sciencedaily.com/release...60816083120.htm

Taking statins to lower cholesterol will lower hormones. So what does mainstream medicine do? They will give replacement hormone therapy!!! Now how ass backwards is that?

I know of a brilliant naturopath that uses coconut oil for his patients with prostrate poroblems and he has amazing success.
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  #12   ^
Old Tue, Dec-26-06, 20:54
Whoa182's Avatar
Whoa182 Whoa182 is offline
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Plan: CRON / Zone
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Default

In that article it mentioned "insulin resistance" as one of the problem associated with low testosterone...

Erm, no this is not always the case at all. I don't think its the low T causing the deaths, I think there is another causative factor which results in both early death and Low T.
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  #13   ^
Old Wed, Dec-27-06, 09:44
Gostrydr Gostrydr is offline
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  #14   ^
Old Wed, Dec-27-06, 13:24
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Mutant Mutant is offline
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Plan: DiPasquale Radical Diet
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Quote:
Originally Posted by Whoa182
Okinawans have almost half the number of broken hips as americans, and are less likely to die from them when they do have them. They also have cholesterol of around 150mg/dl... and quite a few are vitamin D deficient. They also have BMI's of around 18-22 mind you, far more leaner, smaller bones, yet less fractures.


Inferring bone density/health from hip fractures is like inferring bodyfat from Body Mass Indeces - crap. The more active a culture/society is, the more likely of hip fracture. I posit that the reason the Okinawans have less hip fractures is that their frail frames and general lethargy from years of enduring a semi-starved state have robbed them of the ability to engage in vigorous activities that would result in great numbers of hip fracture.

Quote:
Originally Posted by Whoa182
See the link to look at Okies vs americans and the hormone DHEA. It shows a lower amount at first, but it has a much slower decline. The same is quite true for Testosterone in okinawans... yes it is initially lower, but they have a slower decline again. I'm not even sure that having really high level of these hormones is even a good thing!


When your hormone levels are already in the basement, you don't have far to fall. In any event, we aren't talking about HIGH levels of these hormones but NORMAL levels. The Okinawans are ABNORMALLY low.
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  #15   ^
Old Wed, Dec-27-06, 13:26
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Mutant Mutant is offline
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Plan: DiPasquale Radical Diet
Stats: 301.5/260.2/260 Male 71
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Quote:
Originally Posted by Whoa182
In that article it mentioned "insulin resistance" as one of the problem associated with low testosterone...

Erm, no this is not always the case at all. I don't think its the low T causing the deaths, I think there is another causative factor which results in both early death and Low T.



Got a rat or monkey study to back that up?
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