Thu, Oct-06-11, 16:29
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Senior Member
Posts: 3,423
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Plan: Atkins (loosely)
Stats: -/-/-
BF:
Progress: 40%
Location: Ottawa, Ontario
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I don't see why you would be flamed for pointing something out that seems out of place. This isn't a vegan forum girl!
But anyway, this U shaped thing must be some statistical gobbledygook that I failed to understand properly because in the study conclusion they say :
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Based on epidemiological analysis of updated and comprehensive population data, we found that the underlying assumptions regarding cholesterol in clinical guidelines for CVD prevention might be flawed: cholesterol emerged as an overestimated risk factor in our study, indicating that guideline information might be misleading, particularly for women with ‘moderately elevated’ cholesterol levels in the range of 5–7 mmol L-1. Our findings are in good accord with some previous studies. A potential explanation of the lack of accord between clinical guidelines and recent population data, including ours, is time trend changes for CVD/IHD and underlying causal (risk) factors.
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And more gobbledygook here :
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To address the question of whether the U-shaped association was age-dependent in the HUNT population, we performed an age-stratified Cox-regression analysis post-hoc. The results indicated a U-shaped association of cholesterol with CVD mortality among men aged 40–74, and an inverse association among women aged 60–74. Because of limited statistical power, we refrain from emphasizing these results. Seen in the light of previous studies [37,55,58,61,64–66,73–77], it is possible that a U-shaped association is primarily a phenomenon related to people aged 60 years and older.
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