Quote:
Originally Posted by Baal
I would like to know how weight loss occurs in a simply calorie deficit diet where no attention is paid where the calories come from.
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Here's the way I understand it:
Generally speaking cells in the body can use sugar or fat for energy.
It will use sugar first from within the cells (about 500grams stored as glucogen throughout the body). Then, when the pancreas alpha cells detect a drop in BS, it will send out a signal to the liver to release its 100grams of glucogen.
At the same time the beta cells really reign in the release of insulin thereby dropping it to a level that allows fat cells to release fat cell triglycerides into the blood stream. A triglycerides is a giant molecule with a glycerol backbone and 3 fatty acid molecules attached to it.
When the triglyceride molecule arrives inside the liver, it's broken apart and the 3 fatty acids are released back into the blood stream. The liver keeps the glycerol backbone for sentimental reasons.
At about the same time cells in the body have converted the last of their stores of sugar for energy production and begin shifting to fatty acids as a alternate energy source. Newly created fatty acids released into the blood stream travel around to find hungry cells. Since the fatty acids are now much smaller than the original triglycerides, they’re absorbed easily by cells.
The liver continues with the left over glycerol-backbones making glucose and shipping it off via the bloodstream to the brain. The brain likes glucose to keep it happy.
Since the insulin is shut down the body’s cells are “locked” from taking up glucose and any blood sugar. At the same time glucose cannot be converted back to fat until the insulin is allowed to rise again in the blood stream.
Since the body doesn’t have sugar to run on it goes to the next best thing: Fat. And the body seems to get along just fine in its newly altered state of consciousness.
That’s about all there is to it; that and a few million details.
A little known fact is that actual depleted muscle cells in ketosis look like little shriveled-up, featherless baby robins with mouths open. When the fatty acid molecule goes by it looks like a wiggling worm and gets snatched up by the little bird. Amazing but true.
The short verison: little birds eat the fat when you make worms.