Active Low-Carber Forums - View Single Post - Denise Minger returns....In Defense of Low Fat

http://www.ncbi.nlm.nih.gov/pmc/art...a00273-0059.pdf

Kempner might have "cured" diabetes in adults. Meanwhile, in parts of the world where people had little choice but to eat diets similar to the Rice Diet, at least in macronutrient content, there's something sometimes called "J" diabetes. Sort of like type II, but patients generally aren't obese. Protein deficiency seems to be involved in the development. Cyanide can cause a kind of diabetes in rodents, protein deficiency makes it worse--because various amino acids are involved in the detoxification process. That's one theory, anyways. I could see the kind of high carb, very low fat diet being eaten during the post-weaning years of development just plain causing inappropriate development, and poor adaptation to a more varied diet, should it become available.

Quote:

J type diabetes is grouped as a subtype of type
Ill or malnutrition-related diabetes, known as
protein-deficient pancreatic diabetes, (PDPD).
J type diabetes has not been reported recently,
but a clinical picture called phasic insulindependent
diabetes mellitus (PIDDM) has been
elaborated in Jamaica, the same home country
of PDRD and appears to be a "formes frustes"
syndrome.
The following comparative studies were performed
on a group of diabetic patients and
normal controls: insulin receptor binding;
renal, hepatic, and pancreatic function; and
abdominal ultrasonography. The results show
a considerably decreased white and red blood
cell binding to insulin (P<.05), extensive kidney
damage (P<.05), and increased pancreatic
echogenicity in PIDDM, supporting a separate
identity of this latter syndrome from types I and
11 diabetes mellitus. Also, the features of relative
insulin resistance, absence of ketosis even
in the presence of severe hyperglycemia, and
intermittent insulin requirement suggests that
PIDDM, J type diabetes, and PDPD are one and
the same syndrome.