Actually, saccharin is preferred over aspartame. The research done on laboratory animals was the equivalent of some outrageous number... like 40 ounces a day (total guess) ... no human could ingest that much saccharin if he tried!!! In the grand scheme of things, if used moderately, saccharin is safe to use....much safer than aspartame. Here's an article I found that states in 2000 it was dropped from the list of known carcinogens!