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Old Mon, Jun-15-09, 08:16
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Hutchinson Hutchinson is offline
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Plan: Dr Dahlqvist's
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Default More Aggressive Vitamin D Supplementation Needed in Obese Cancer Patients

More Aggressive Vitamin D Supplementation Needed in Obese Cancer PatientsCHICAGO, June 15 /PRNewswire-USNewswire/ -- Body mass index (BMI) should be taken into account when assessing a cancer patient's vitamin D status, according to researchers at Cancer Treatment Centers of America (CTCA), who found that obese cancer patients had significantly lower levels of vitamin D compared to non-obese patients.

The association between vitamin D and obesity remains unsettled with studies reporting conflicting findings on the relationship between the two. This association assumes even greater importance in cancer because of the alleged role of vitamin D in cancer.

"Currently, the dietary recommendations for vitamin D do not take into account a patient's BMI," said Carolyn Lammersfeld, national director of nutrition for CTCA and a principal investigator in the study. "We investigated the relationship between vitamin D and BMI in a large sample of cancer patients and found that as BMI groups increased from normal to overweight or obese classifications, there was a significant decrease in vitamin D."

The researchers evaluated a group of 740 cancer patients seen at CTCA from January 2008 to June 2008. Of the 740 patients, 303 were male and 437 female, with a mean age at presentation of 55.7 years (SD = 10.2). The mean BMI was 27.9 kg/m2 (SD = 6.7). The most common cancers were lung (134, 18.1%), breast (131, 17.7%), colorectal (97, 13.1%), pancreatic (86, 11.6%), prostate (45, 6.1%) and ovarian (39, 5.3%). The mean vitamin D (serum 25(OH)D) was 21.9 ng/ml (SD = 13.5).

The study concluded that obese cancer patients (BMI >=30 kg/m2) had significantly lower levels of vitamin D compared to non-obese patients (BMI <30 kg/m2). BMI should be taken into account when assessing a patient's vitamin D status and more aggressive vitamin D supplementation should be considered in obese cancer patients, researchers determined.

This study was presented at the American Society of Clinical Oncology (ASCO) annual meeting, May 29-June 2, 2009, and was publicly released on ASCO's Web site, on May 14, 2009.


YouTube - Vitamin D and Cancer Prevention
In case anyone isn't aware the level associated with least cancer incidence and best prognosis is over 55ng
To get from the average of those cancer patients approx 22ng to 55ng requires AT LEAST 3500iu maybe in practice 5000~6000iu/d (the higher your vitamin D status gets, the harder it becomes to raise status, more is being diverted to storage)

Low Vitamin D May Be Root Cause of Cancer In fact, Dr. Garland and his team have published epidemiological studies about the potential preventive effects of vitamin D for some twenty years. Again someone here cannot do simple arithmetic. Do sunlight and vitamin D reduce the likelihood of colon cancer? was published in 1980 2009-1980=29 so it's more like 30 years work that Garland has put into vitamin D and cancer prevention, it's such a shame people aren't prepared even to spend 40minutes listening to what he is saying let alone spend the few cents/pence it takes to be on the safe side.

Ideal dose of sunshine vitamin? Interesting Vieth's point more complicated" because both low blood amounts and wide annual fluctuation "may be a problem." Indeed we can do something about a wide fluctuation and low levels throughout the year and 2000iu/d is not going to solve those problems, they require somewhat more than 2000iu/d.
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