Active Low-Carber Forums - View Single Post - Allulose reduces post-prandial glucose

Interesting study!
https://drc.bmj.com/content/9/1/e001939

Quote:

Significance of this study
What is already known about this subject?
D-allulose is defined one of the rare sugars, which has been shown in animal and clinical studies, conducted mostly in Asian populations, to have postprandial plasma glucose suppressive effects with antiobesity and antidiabetic effects.

What are the new findings?
Our study showed that D-allulose administered in addition to a standard sucrose load led to a dose-dependent reduction of plasma glucose at 30 min compared with placebo with a dose-dependent reduction in plasma glucose excursion.

The effects of D-allulose on insulin levels and insulin excursion were similar to those on plasma glucose.

D-allulose effects appeared to be consistent in both white and African-American subjects.

The administration of escalating doses of D-allulose appeared to be safe.

How might these results change the focus of research or clinical practice?
The results of our investigation can set the basis for the potential use of D-allulose in a population where reduction of added sugar is of paramount importance.

The present study suggests that adding 5–10 g of D-allulose to 50 g of sugar is sufficient to reduce the postprandial glycemia attributed to sugar.

This ratio of D-allulose to sugar content is consistent with the composition of the currently marketed rare sugar syrup and is well tolerated.

Future studies should explore more in depth the underlying mechanisms by which D-allulose reduces glucose and insulin levels as well as its long-term effects, including its potential to impact clinically meaningful outcomes.