I did the 6-week cure in 2009 and lost about 5 pounds. That was OK, but not spectacular.

But, i was miserable for the first two weeks. I had terrible insomnia, which is rare for me. I got so tired that I wasn't functioning well at work. I websearched and discovered that milk thistle can cause insomnia. Once I cut out the milk thistle, I immediately could sleep again. A few other people on this board had the same experience.