This weekend, I met a girl that has an underactive thyroid. She is extremely overweight and it has effected her mentally and physically. she is very depressed. she was told by her doctors that it is hopeless that she will lose weight. I was suprised by that comment, and decided to look into this a bit further for her. I am glad that I came here today, because after doing some research and reading some of your posts here, I know that there is hope for her. I also read some interesting information regarding this at the about.com. website. I know how difficult it is to lose weight without having a medical problem, so i realize that this is tremendously difficult for her and others who have thryroid problems. but to hear her say to me that she was told it is hopeless that she will ever lose weight broke my heart. she had such despair in her face. but i am going to recommend this website to her for some encouragement, support and guidance.