It seems to back up a suspicion that has floated around nutritional musings for years that carbs and fat have an antagonistic relationship in a damaged system. You can eat one or the other, but not both "in moderation." We all know that alcohol is metabolized before anything else, which suggests the body gives other macros a priority number. That may very well not be the case for dietary fat and carbohydrates, which could require multitasking a damaged system is incapable of. The system seems to scream "abandon ship!" and begins dumping all kinds of nasties into itself. Hopefully as the years wear on, scientists will give this notion a bit of credence and really dive in to it.

It overall also questions the idea of a "varied diet" being necessary for health. An animal system is highly adaptable but also enjoys some stability.

I just know, personally, a very low fat diet leaves me feeling terrible. I've tried it and really had a hard time adapting.