O'Keefe is a preventative cardiologist and author. Interesting podcast that covers everything related to and associated with cardiovascular disease. From healthy & unhealthy exercise to CAC to supplements to statins to SGLT2 inhibitors to lifestyle changes promoting longevity. I don't agree with everything stated, but it's a very useful dialog for those dealing with the topic:

https://peterattiamd.com/jamesokeefe/