Tue, Jun-26-18, 06:34
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Plan: P:E/DDF
Stats: 225/150/169
BF:45%/28%/25%
Progress: 134%
Location: NC
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ADA annual meeting
The scientific sessions of the ADA are happening this week. Yesterday and today MedPage News was all about diabetes...drugs that is.
This morning's lead article....
Quote:
Early T2D Treatment in Youth Disappoints
Metformin, insulin didn't stop deterioration of beta-cells in adolescents with impaired glucose
by Kristen Monaco, Staff Writer, MedPage Today June 25, 2018 ORLANDO --
Early pharmacologic intervention did not stop disease progression in youth with impaired glucose tolerance (IGT) or recently diagnosed type 2 diabetes, researchers reported here.
Neither treatment with 12 months of metformin alone nor 3 months of insulin glargine, followed by 9 months of metformin, prevented the progression of β-cell deterioration in young patients with IGT or recently diagnosed type 2 diabetes, according to Sharon Edelstein, of the Biostatistics Center at George Washington University in Washington, and colleagues in The RISE Consortium.....
Article continues with all the details of pharmaceuticals doing nothing to stop the progression of disease. Disappointed with results. So sad, seems bariatric surgery only solution. It gets worse...
"This was not what anybody predicted based on everything we see in adults, where intensive insulin therapy preserves beta cells, and where metformin is shown to be effective in adults as a first-line therapy and in prevention," explained co-author Steven Kahn, MB, ChB, of the University of Washington in Seattle at an ADA press conference.
The authors were disappointed by the results, he noted.
"We are not spinning around and saying not to use insulin or not to use metformin if you're a treating physician -- you have to carry on using these," Kahn stressed. "We had hoped that earlier, aggressive intervention would have had a much more beneficial effect than what we'd seen. We're not turning around and saying don't treat these kids with the drugs that are approved."
https://www.medpagetoday.com/meetingcoverage/ada/73697?
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So for two days, dozens of articles on drugs, mostly having little or no results.
As Dr Hallberg has stated the Virta results are not shared at meetings like this, it must be so frustrating. But this study write-up was particularly depressing.
https://www.medpagetoday.com/endocrinology |