I do not do Pilates, but I do Tae-Bo and some other cardio tapes. Haven't seen a problem with lifting. Maybe Pilates are different though. Pilates focuses on core muscle groups, right? I just don't see how doing a Pilates class 2X per week would seriously cause difficulties with weight lifting, unless you are doing them on the same day. Sorry I am not much of a help. Hope you gets this all figured out. I know how frustrating it can become, when you try so hard, and only seem to be back-pedaling.