CoQ10 and insulin resistance
https://www.sciencedaily.com/releas...80207110109.htm
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Obvious possible tie-in here between statins and diabetes. Blood lipids as a proxy for synthesis of other essential lipid byproducts is interesting. |
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Obvious possible tie-in here between statins and death in general. |
Pretty sorry how statins are deliberately prescribed to people because they have diabetes. I was offered one. NO THANKS! I need my CoQ10, ketones, muscles, heart, and life!
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The Keys-backed Lipid Theory was based on shoddy science, so how long before the statins, which are based on that theory, will come off the market?
The world is supposed to work that way, we flatter ourselves. |
These are the two lines that got my attention:
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Right, first reaction is to make sure we are stocked up on CoQ10 supplements. Awww, not so fast, as they are anecdotally described as being characterized by low absorption with the "may not effectively" caveat. |
Yup. With the live mouse study, they injected the CoQ10. Maybe you could get some effects with very large oral doses, but the stuff's so expensive as it is.
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I've been seeing this article everywhere. It's interesting, but the mechanism isn't fully explained. Did the insulin resistance lead to low CoQ10, or the other way around? I think they can make more money from a drug that helps increase CoQ10 levels vs recommending CoQ10 supplements. They fail to mention that water and fat-soluble ubiquinol can bring blood levels up pretty darn high. |
There has been quite a bit of research on CoQ10.
http://lpi.oregonstate.edu/mic/diet...rs/coenzyme-Q10 |
OK, watch this.
It's not just about CoQ10, it's also about ROS and obviously about antioxidants. Well, ketones are powerful antioxidants. Check this out: https://www.sciencedirect.com/scien...014488608000101 Doesn't stop there. Based on my paradigm (sorry, I forgot who exactly gave me the following idea, but it's fairly recent), ketones activate insulin receptors in the liver, which in turn means the absence of ketones is the proximal cause (i.e. the immediate mechanism) of insulin resistance. The primary cause, of course, is a high-carb diet. It's exquisitely ironic that we test for insulin resistance with an oral glucose tolerance test. The point is ketones take care of ROS when there's too much ROS. Then, when ketones aren't there, well, they don't take care of any ROS, excess or otherwise. And if it's true that some ROS can cause insulin resistance (more than absence of ketones), we get a runaway effect. Never mind CoQ10 at this point. It's just so much easier to fix the ketones problem. It's probably also gonna fix about 90% of the CoQ10 problem, ya know, while we're there. |
Don't we get CoQ10 from meat? Even though meat will kill us? /sarcasm
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It's absurd that meat, which contains necessary nutrients not found in sufficient quantities in other substances, are demonized as health risks. As we all know B12 is only found in meats and CoQ10 is found primarily in meats and in greatest abundance in animal hearts which is why I eat heart regularly. I grind it up and stir fry it with vegetables. Jean |
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Yes, it should considering ketones and CoQ10 are both produced via the same HMG-CoA reductase pathway. Get that up and running right and you should have plenty of both, along with cholesterol and other life-giving substances this pathway is responsible for making. A really insidious thing about statins is they deliberately target this pathway, cutting back our ability to produce all of these highly valuable and necessary substances, all in the name of the old discredited cholesterol-causes-heart-disease myth. Scary! :( |
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