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Exploring the untapped potential of low-carbohydrate diets

In the current issue of Current Opinion in Endocrinology, Diabetes and Obesity:

Quote:

Editorial: Exploring the untapped potential of low-carbohydrate diets

Westman, Eric C

Current Opinion in Endocrinology & Diabetes and Obesity: October 2020 - Volume 27 - Issue 5 - p 253-254
doi: 10.1097/MED.0000000000000563

https://journals.lww.com/co-endocri...ntial_of.2.aspx

Quote:

Using a low-carbohydrate diet to treat obesity and type 2 diabetes mellitus

Westman, Eric C.; Yancy, William S. Jr

Current Opinion in Endocrinology & Diabetes and Obesity: October 2020 - Volume 27 - Issue 5 - p 255-260
doi: 10.1097/MED.0000000000000565

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This study will provide a narrative review of the history of the clinical use of low-carbohydrate diets and give a practical example of how to implement a low-carbohydrate diet, with an emphasis on deprescribing medications.

https://journals.lww.com/co-endocri...sity_and.3.aspx

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The biochemistry of low-carbohydrate and ketogenic diets

Feinman, Richard D.

Current Opinion in Endocrinology & Diabetes and Obesity: October 2020 - Volume 27 - Issue 5 - p 261-268
doi: 10.1097/MED.0000000000000575

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To summarize the underlying biochemical basis for low-carbohydrate and ketogenic diets (LC/KD) and provide mechanisms to account for demonstrated effectiveness.

https://journals.lww.com/co-endocri...etogenic.4.aspx

Quote:

Effect of low-carbohydrate diets on cardiometabolic risk, insulin resistance, and metabolic syndrome

O’Neill, Blair J

Current Opinion in Endocrinology & Diabetes and Obesity: October 2020 - Volume 27 - Issue 5 - p 301-307
doi: 10.1097/MED.0000000000000569

Quote:

An obesity epidemic has resulted in increasing prevalence of insulin resistance, hyperinsulinemia, metabolic syndrome (MetS), and cardiovascular disease (CVD). The Diet-Heart Hypothesis posited that dietary fat is the culprit. Yet dietary fat reduction has contributed to the problem, not resolved it. The role of hyperinsulinemia, the genesis of its atherogenic dyslipidemia and systemic inflammation in CVD and its reversal is reviewed.

https://journals.lww.com/co-endocri...diets_on.9.aspx

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Low carbohydrate ketogenic therapy as a metabolic treatment for binge eating and ultraprocessed food addiction

Sethi Dalai, Shebania; Sinha, Anikab; Gearhardt, Ashley N.

Current Opinion in Endocrinology & Diabetes and Obesity: October 2020 - Volume 27 - Issue 5 - p 275-282
doi: 10.1097/MED.0000000000000571

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The aim of this study was to highlight the recent advancements and future directions for potential use of a low carbohydrate ketogenic dietary approach to treat binge eating and ultraprocessed food addiction. Herein, we explore proposed mechanisms of why a diet low in refined carbohydrates, processed sugar and higher fat content may be helpful in alleviating symptoms.

https://journals.lww.com/co-endocri...etabolic.6.aspx

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Reversal of severe hypertriglyceridemia with intermittent fasting and a very-low-carbohydrate ketogenic diet: a case series

Das, Subrata; McCreary, Jordanb; Shamim, Shariqc; Kalayjian, Trod,

Current Opinion in Endocrinology & Diabetes and Obesity: October 2020 - Volume 27 - Issue 5 - p 308-311
doi: 10.1097/MED.0000000000000566

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To illustrate successful reversal of hypertriglyceridemia using a very-low-carbohydrate ketogenic diet in conjunction with intermittent fasting in two patients.

https://journals.lww.com/co-endocri...ia_with.10.aspx

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Ketogenic diet as a metabolic treatment for mental illness

Norwitz, Nicholas G.; Dalai, Shebani Sethi; Palmer, Christopher M.

Current Opinion in Endocrinology & Diabetes and Obesity: October 2020 - Volume 27 - Issue 5 - p 269-274
doi: 10.1097/MED.0000000000000564

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Ketogenic diets, which have been used to treat drug-refractory paediatric epilepsy for over 100 years, are becoming increasingly popular for the treatment of other neurological conditions, including mental illnesses. We aim to explain how ketogenic diets can improve mental illness biopathology and review the recent clinical literature.

https://journals.lww.com/co-endocri...r_mental.5.aspx

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The potential of a ketogenic diet to minimize effects of the metabolic fault in glycogen storage disease V and VII

Reason, Stacey L.; Godfrey, Richard J.

Current Opinion in Endocrinology & Diabetes and Obesity: October 2020 - Volume 27 - Issue 5 - p 283-290
doi: 10.1097/MED.0000000000000567

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To explore the potential of a low carbohydrate ketogenic diet (LCKD) to counter physical activity intolerance, pain and muscle damage for glycogen storage disease (GSD) V and VII, and highlight the realistic possibility that nutrition could be key.

https://journals.lww.com/co-endocri...minimize.7.aspx

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Can a carnivore diet provide all essential nutrients?

O’Hearn, Amber

Current Opinion in Endocrinology & Diabetes and Obesity: October 2020 - Volume 27 - Issue 5 - p 312-316
doi: 10.1097/MED.0000000000000576

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The aim of this study was to summarize current contributions affecting knowledge and predictions about the nutritional adequacy of plant-free diets, contextualized by historical accounts.

https://journals.lww.com/co-endocri...sential.11.aspx

https://journals.lww.com/co-endocri...currenttoc.aspx

Many thanks for posting all of these article links. :clap:

I had posted the pre-print version of Dr Westman's Editorial on August 13th below, but that version has now been removed and the link is broken.
This is fantastic! You take the time to include direct links to every one of the titles. Now if more endocrinologists would read the whole issue.

Demi, I am constantly in awe of your posts. And very appreciative of all the time you take to share these studies with us - especially providing the links.

Thank you

The links are great, but only if you're a subscriber, which costs $1,327 for a one-year subscription. Too bad. I would like to have read some of these. Dr. Westman is one of the healthcare professionals I most admire.

Excellent topics. These study titles have me interested but, like Bawdy, not enough to pay to read them. Here's hoping general access will be available at some point.

WOW! Thank you Demi! Thank you!

I would like to add that for me, the abstracts are often enough to get the gist of where the research is going, but I’ve also found that many times if you have the time and patience, the studies can be found elsewhere on the internet.

Thanks! I find such links alone are good to have for people who make fun of me for the way I eat.

I'm not falling for psuedo-science. I'm not a "sheep." If the way I look and feel now is not compelling, here's some science.

(Yes, the irony of vegans calling me a sheep is noted.)

I agree WereBear. It still amazes me in this day and age people still call low carb dangerous. Nobody used those words in the 1980’s/early 90’s fat free era, when I was piling on the fat free sugar and white flour in my fat free cookies!

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Originally Posted by sheryl2020

Likewise, I was restricting myself to 25 grams of fat a day, AND working out 1.5 hours a day. To lose down to 150. Which I thought was okay at the time.

And the reason I blew past my goal on low carb :wave: I've been an adult a long time and never got to my real adult weight :agree:

Werebear, congratulations on your goal. You are a true success story!

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Originally Posted by sheryl2020

Werebear, congratulations on your goal. You are a true success story!

Thank you. Never give up, never surrender! :lol:

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Originally Posted by WereBear

Thank you. Never give up, never surrender! :lol:

X 2 Just dont quit trying.

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Originally Posted by WereBear

I was thinking about you earlier today WereBear. I had stumbled onto another one of those atrocious "articles" you find all over the place and it was decrying low-carb diets as not being sustainable and only good for making you lose water weight. I immediately thought of you and the fact that the writer of that "article" is basically saying you've lost 100lb of water. Umm okay. I'm gonna have to call BS on that one.

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Originally Posted by BawdyWench

If anyone's interested, you can find many of these journals in their entirety here: https://booksc.org/s/?q=Endocrinolo...and+obesity&e=1