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  #1   ^
Old Tue, Jan-10-17, 04:27
teaser's Avatar
teaser teaser is online now
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Default High cholesterol intake and eggs do not increase risk of memory disorders

Quote:
High cholesterol intake and eggs do not increase risk of memory disorders

A new study from the University of Eastern Finland shows that a relatively high intake of dietary cholesterol, or eating one egg every day, are not associated with an elevated risk of dementia or Alzheimer's disease. Furthermore, no association was found in persons carrying the APOE4 gene variant that affects cholesterol metabolism and increases the risk of memory disorders. APOE4 is common in Finland. The findings were published in the American Journal of Clinical Nutrition.

High serum cholesterol levels have been linked not only to an increased risk of cardiovascular diseases, but also to an increased risk of memory disorders. In the majority of the population, dietary cholesterol affects serum cholesterol levels only slightly, and many nutrition recommendations worldwide no longer set limitations on the intake of dietary cholesterol. In carriers of APOE4, however, the effect of dietary cholesterol on serum cholesterol levels is more visible. In Finland, the prevalence of APOE4, which is a hereditary variant, is exceptionally high and approximately one third of the population are carriers. APOE4 is a risk factor of both cardiovascular diseases and memory disorders. However, research data on the association between a high intake of dietary cholesterol and the risk of memory disorders in this population group hasn't been available until now.

The dietary habits of 2,497 men aged between 42 and 60 years and with no baseline diagnosis of a memory disorder were assessed at the onset the Kuopio Ischaemic Heart Disease Risk Factor Study, KIHD, in 1984-1989 at the University of Eastern Finland. During a follow-up of 22 years, 337 men were diagnosed with a memory disorder, 266 of them with Alzheimer's disease. 32.5 per cent of the study participants were carriers of APOE4.

The study found that a high intake of dietary cholesterol was not associated with the risk of dementia or Alzheimer's disease -- not in the entire study population nor in the carriers of APOE4. Moreover, the consumption of eggs, which are a significant source of dietary cholesterol, was not associated with the risk of dementia or Alzheimer's disease. On the contrary, the consumption of eggs was associated with better results in certain tests measuring cognitive performance.

The findings suggest that a high-cholesterol diet or frequent consumption of eggs do not increase the risk of memory disorders even in persons who are genetically predisposed to a greater effect of dietary cholesterol on serum cholesterol levels than others. In the highest control group, the study participants had an average daily dietary cholesterol intake of 520 mg and they consumed an average of one egg per day, which means that the findings cannot be generalised beyond these levels.


https://www.sciencedaily.com/releas...70109093015.htm


Similar headline from last year (also some of the same names on the research team, same university). With the same punchline--do not generalize beyond these levels. To me, this means do not assume that more cholesterol than that 520 mg a day is safe--but also don't assume that it's dangerous.

Quote:
High-cholesterol diet, eating eggs do not increase risk of heart attack, not even in persons genetically predisposed, study finds


https://www.sciencedaily.com/releas...rendmd-shared=0
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  #2   ^
Old Tue, Jan-10-17, 07:46
WereBear's Avatar
WereBear WereBear is offline
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It never was real science!
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  #3   ^
Old Tue, Jan-10-17, 07:47
khrussva's Avatar
khrussva khrussva is online now
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Default

Nice to hear. I like eggs and I always want to remember that.
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  #4   ^
Old Tue, Jan-10-17, 10:55
GRB5111's Avatar
GRB5111 GRB5111 is offline
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For those with the APOE4 gene variant, great news! I've often wondered how much of an actual health risk is the higher cholesterol levels in those with APOE4. While it's still an epidemiological study, the findings are encouraging.

Now to go cook some eggs . . . .
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  #5   ^
Old Tue, Jan-10-17, 12:07
SabreCat50 SabreCat50 is offline
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Default Not very many eggs...

Quote:
Originally Posted by teaser
https://www.sciencedaily.com/releas...70109093015.htm

A new study from the University of Eastern Finland shows that a relatively high intake of dietary cholesterol, or eating one egg every day,...

https://www.sciencedaily.com/releas...rendmd-shared=0


One egg a day yields relatively high intake of cholesterol?? I normally consume 3 or 4 eggs a day!
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  #6   ^
Old Thu, Jan-12-17, 08:04
WereBear's Avatar
WereBear WereBear is offline
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Default

It's all BS. Fat is our friend when it comes to our brain.

You know what's causing the epidemic of Alzheimer's and dementia? I think (and I'm not alone) it is the double whammy of low fat and statins.

Not eggs.
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  #7   ^
Old Thu, Jan-12-17, 09:14
Zei Zei is offline
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As a person with probable APOE4 this sort of thing interests me. I also wonder how much of an actual health risk my high cholesterol might be, but answers seem pretty hard to come by. Saturated fat definitely elevates already high LDL significantly higher, but a low saturated fat (based on olive oil, nuts etc.) drops HDL into the basement and saturated fat brings it back up. Doctor of course wants to drug down my LDL with things that have little or no benefit but plenty of devastating side effects, so I consistently decline. Since HDL and LDL for me move up and down in lock-step together depending on the amount of saturated dietary fat (haven't yet found a way to make one go up and the other down), until more information is known I'm currently going for higher HDL hoping that's the more important one to target. That said, I really appreciate this study being posted here because I was wondering if I'd have to cut out cholesterol/eggs, too.
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