Fascinating interview about circadian rhythm, time restricted feeding and various health benefits. While this is not low carb research it really synchs with it. It's a long interview but really well worth listening to:

https://www.youtube.com/watch?v=-R-eqJDQ2nU

Rhonda Patrick, who conducts the interview, has an interesting website with many interesting talks and interviews. Her primary interest is micronutrients. She does basic biochemistry research but her mind clearly roams over all things impacting human health and she utilizes what she learns to direct aspects of her own life.

Her website:

https://www.foundmyfitness.com/

Jean

I haven't listened to the video, but I went to the website and dug deeper and found a gem.

Metformin is showing signs of anti-aging properties as a side effect. There is an anti-aging drug beginning testing in Japan next month. Of course, the process of getting it out to the populace can take up to 10 years.

Glenda - I find myself much more interested in lifestyle changes that I can make to affect aging than I do the development of drugs. That's what I found so fascinating about the video. It is about the timing of eating and sleeping and exposure to light that we can all make in our own lives that may have considerable health benefits and not cost us a penny nor enrich the pockets of a drug company. There's an interesting website with a blog and other things and even a research study you can participate in if you so choose:

http://mycircadianclock.org/

From my perspective this information just adds a new dimension to optimizing health.

Jean

I'll be looking into it. Thanks.

I agree with you, Jean... lifestyle changes are much more effective, and profound, for optimizing health than taking meds.

I was excited about joining the circadian study... until I found it requires a smartphone. Alas, I'm not smart enough for a smartphone.

Well, I installed the app and am doing my best to learn how to use it. I think it's basically a waste of time. I'm going to uninstall.

Thanks for this post Jean. I like her interviews and this topic, will listen later when have time. Somewhere here previously posted her talk with Dom D'Agastino on Cancer that had mentions of longevity.

Glenda - The talk is still really interesting and it's only at the very end that they talk about the research that uses the app. I posted about the talk primarily, not the app and participating in the research. I haven't decided yet whether or not I will participate but I am planning to incorporate some of the information from the talk about timed eating into my routine.

Jean

I decided to participate in the study or at least I intend to unless I decide that it is too onerous to take pictures of everything I eat. This research on circadian rhythm as it applies to eating adds another dimension to the subject of fasting, that the timing of eating independent of calories and food composition, effects weight. Of course the studies have been extensively done only in mice. This research is an attempt to expand upon the initial pilot study in humans, which was mostly a pilot study of the app, so that it can be known whether what was shown to be true in mice is also true for humans. Anyway, it interests me and I am going to give it a go. The primary researcher is Satchin Panda and he impresses me as one of those people with a far ranging mind but the ability to simplify things and make them understandable.

Jean

Thanks for the link, Jean. Started watching and will watch in increments over the next couple days. Rhonda Patrick is very good and has excellent guests. She has extensive knowledge which makes the interviews that much better.

Time-restricted Feeding / IF must be getting too popular. My local paper just had an article saying there was no proof it helped people lose more weight than the low-cal diet that Registered Dogmatists push.

Deirdra - Satchan Panda, the researcher, has as his primary interest circadian rhythm. He came upon this notion of a circadian rhythm for eating that was distinct from the circadian rhythm for light and dark through his mouse studies. He is not primarily an obesity/weightloss/diet researcher. His interest in human studies seems to have developed through his observations about mice. He says in this interview that he used a term different from "Intermittent Fasting" because he wanted to make it clear that what he is studying has no relationship to calorie restriction which he says is often associated with the term "IF". He is based at the Salk Institute in California. Here's his description from the Salk Institute site:

"Satchidananda Panda explores the genes, molecules and cells that keep the whole body on the same circadian clock. A section of the hypothalamus called the suprachiasmatic nucleus (SCN) lies at the center of the body’s master clock and gets input directly from light sensors in the eyes, keeping the rest of the body on schedule. Panda discovered how these light sensors work, as well as how cellular timekeepers in other parts of the body function. He also uncovered a novel blue light sensor in the retina that measures ambient light level and sets the time to go to sleep and wake up every day.

In the process of exploring how the liver’s daily cycles work, Panda found that mice which eat within a set amount of time (12 hours) resulted in slimmer, healthier mice than those who ate the same number of calories in a larger window of time, showing that when one eats may be as important as what one eats. If the benefits of this “12-hour diet” hold true in humans, it could have profound impacts on treating overeating disorders, diabetes and obesity."

He's not just another IF wannabe.

Jean

Don't miss the follow-up on Time Resistricted eating and Breast Cancer with Dr Ruth Patterson, UCSD Cancer Center.
https://youtu.be/8qlrB84xp5g

I watched that too Janet. It's so interesting when research from various people with different starting interests begins to converge. Makes you believe that they're onto something .

Jean

Thanks for posting. Always looking for something to work out to.



I'm not sure I'd contest this, personally, I didn't go low carb because I failed to lose weight restricting calories. As far as that goes, I must have successfully lost weight on low calorie/low fat at least six or seven times.