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  #76   ^
Old Sat, Feb-07-15, 09:25
WereBear's Avatar
WereBear WereBear is offline
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Plan: Epi-Paleo/IF
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Nancy LC, that's very encouraging news for your brother. My best to everyone over this situation.
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  #77   ^
Old Sat, Feb-07-15, 09:33
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Jamackarch Jamackarch is offline
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Plan: hflc
Stats: 166/159/125 Female 5'2"
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Progress: 17%
Location: Pacific Northwest
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Quote:
Originally Posted by WereBear
...It takes incredible will, and extraordinary confidence, to think outside the box. Everyone here has done it.
But we know how much it takes to swim against the tide.


Hear, hear.
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  #78   ^
Old Mon, Feb-09-15, 09:47
Nancy LC's Avatar
Nancy LC Nancy LC is offline
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Posts: 45,170
 
Plan: Paleo 99.5%
Stats: 210/170/160 Female 67.5"
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Progress: 80%
Location: San Diego, CA
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  #79   ^
Old Mon, Feb-09-15, 13:11
WereBear's Avatar
WereBear WereBear is offline
Posts: 9,835
 
Plan: Epi-Paleo/IF
Stats: 220/162/150 Female 67
BF:
Progress: 83%
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Thanks, Nancy! I've come to believe inflammation is the root of all evil... or at least 90% of our sickness issues!
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  #80   ^
Old Sat, Feb-14-15, 13:01
JEY100's Avatar
JEY100 JEY100 is offline
To Good Health!
Posts: 9,111
 
Plan: IF Fung/LC Westman/Primal
Stats: 222/172/169 Female 5' 9"
BF:45%/25.3%/24%
Progress: 94%
Location: NC
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A recent paper by Dr. Seyfried, picked up by PubMed:

http://www.ncbi.nlm.nih.gov/pubmed/25069036

Quote:
Metabolic therapy: a new paradigm for managing malignant brain cancer.

Seyfried TN1, Flores R2, Poff AM3, D'Agostino DP3, Mukherjee P2.

Abstract
Little progress has been made in the long-term management of glioblastoma multiforme (GBM), considered among the most lethal of brain cancers. Cytotoxic chemotherapy, steroids, and high-dose radiation are generally used as the standard of care for GBM. These procedures can create a tumor microenvironment rich in glucose and glutamine. Glucose and glutamine are suggested to facilitate tumor progression. Recent evidence suggests that many GBMs are infected with cytomegalovirus, which could further enhance glucose and glutamine metabolism in the tumor cells. Emerging evidence also suggests that neoplastic macrophages/microglia, arising through possible fusion hybridization, can comprise an invasive cell subpopulation within GBM. Glucose and glutamine are major fuels for myeloid cells, as well as for the more rapidly proliferating cancer stem cells. Therapies that increase inflammation and energy metabolites in the GBM microenvironment can enhance tumor progression. In contrast to current GBM therapies, metabolic therapy is designed to target the metabolic malady common to all tumor cells (aerobic fermentation), while enhancing the health and vitality of normal brain cells and the entire body. The calorie restricted ketogenic diet (KD-R) is an anti-angiogenic, anti-inflammatory and pro-apoptotic metabolic therapy that also reduces fermentable fuels in the tumor microenvironment. Metabolic therapy, as an alternative to the standard of care, has the potential to improve outcome for patients with GBM and other malignant brain cancers.


Found it with a simple PubMed search for Ketogenic And Cancer,
135 citations as of this date. Some critical of all the alternate "cancer diets" but more new ones investigating low carb or keto as beneficial in conjunction with standard of care.

Last edited by JEY100 : Sun, Feb-15-15 at 02:56.
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  #81   ^
Old Sat, Feb-14-15, 13:08
teaser's Avatar
teaser teaser is offline
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Plan: ketosis/IF
Stats: 190/158/154 Male 67inches
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https://www.youtube.com/watch?v=F3VQlWWDtiw

Quote:
Published on Feb 9, 2015
As part of our #TalkingKeto series we filmed key sessions from our 2014 Symposium in Liverpool. This is Professor Adrienne C. Scheck's session about cancer treatment using the Ketogenic Diet.


Spotted this on Youtube today, looking for something to listen to while working out.
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  #82   ^
Old Sat, Feb-14-15, 18:19
JEY100's Avatar
JEY100 JEY100 is offline
To Good Health!
Posts: 9,111
 
Plan: IF Fung/LC Westman/Primal
Stats: 222/172/169 Female 5' 9"
BF:45%/25.3%/24%
Progress: 94%
Location: NC
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Quote:
Originally Posted by teaser
https://www.youtube.com/watch?v=F3VQlWWDtiw
Spotted this on Youtube today, looking for something to listen to while working out.


Teaser, you have posted exactly what I was looking for! saved me tons of time..many, many thanks! Towards the end of this exciting talk, she describes the protocol and testing used to compare results for their clinical trial of a Keto Diet as adjuvant theraphy with chemo and radiation. There aren't many.

Then viewed some of the other talks from this same conference, which of course, consumed way more of that time saved Dr Seyfried's lecture is good too, and more revealing was his shorter overview on Keto and Cancer, including why clinical trials are almost Impossible to find. Depressing, but clear about what an individual must do who does want to try Keto with Cancer treatment. You and your doctor will be on your own, don't expect a hospital, much less a drug company, to support diet as an adjuvant. http://youtu.be/4WitYoTGeno

Last edited by JEY100 : Sun, Feb-15-15 at 02:55.
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  #83   ^
Old Sun, Feb-15-15, 10:01
GRB5111's Avatar
GRB5111 GRB5111 is online now
Posts: 1,672
 
Plan: Ketogenic (LCHFKD)
Stats: 227/186/185 Male 6' 0"
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Location: Herndon, VA
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Extremely informative thread, thanks to all who posted links and information starting with the first Rob Wolfe blog Nancy posted. I'm trying to absorb this, as I've had a few family members who are cancer survivors and some victims. One of the books published a few years ago that got my interest in this topic is by David Servan-Schreiber a scientist / psychiatrist who suffered two separate episodes of brain cancer and after the second dedicated his research focus on potential food/external sources of cancer triggers: Anticancer: A New Way of Life.

Timely, and very detailed, Amy Berger's Tuit Nutrition blog is in the midst of a series comparing the Metabolic Origins Theory (MOT) (where cancer is the result of metabolic abnormalities) and the Somatic Mutations Theory (SMT) (where cancer is the result of mutated DNA). Her multi-series blog on this is very detailed in biochemistry and covers a lot of the information in the Wolfe blog on this topic (yes, another link): http://www.tuitnutrition.com/

I found it very interesting.
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  #84   ^
Old Tue, Mar-03-15, 10:30
teaser's Avatar
teaser teaser is offline
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Plan: ketosis/IF
Stats: 190/158/154 Male 67inches
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https://www.youtube.com/watch?v=SEE-oU8_NSU

Quote:
Thomas Seyfried: Cancer: A Metabolic Disease With Metabolic Solutions


A new IMHC talk.
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  #85   ^
Old Tue, Mar-03-15, 11:35
JEY100's Avatar
JEY100 JEY100 is offline
To Good Health!
Posts: 9,111
 
Plan: IF Fung/LC Westman/Primal
Stats: 222/172/169 Female 5' 9"
BF:45%/25.3%/24%
Progress: 94%
Location: NC
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Thank You for Posting! This is a terrific new lecture by Dr. Seyfried. Since so many lives are touched by cancer, everyone should watch this. Also loved that his sense of humor really shines here, especially in the Q&A.
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  #86   ^
Old Tue, Mar-03-15, 12:43
JEY100's Avatar
JEY100 JEY100 is offline
To Good Health!
Posts: 9,111
 
Plan: IF Fung/LC Westman/Primal
Stats: 222/172/169 Female 5' 9"
BF:45%/25.3%/24%
Progress: 94%
Location: NC
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posted wrong thread..fixed
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  #87   ^
Old Sat, Mar-14-15, 08:59
JEY100's Avatar
JEY100 JEY100 is offline
To Good Health!
Posts: 9,111
 
Plan: IF Fung/LC Westman/Primal
Stats: 222/172/169 Female 5' 9"
BF:45%/25.3%/24%
Progress: 94%
Location: NC
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Received latest Medscape Oncology Newsletter. The intended audience is doctors, but anyone can sign up for Medscape news. The link is to the complete article that may require a member sign-in, but I have copied the Sugar-Free Diet section. The article reviews eight Alternative approaches to cancer, a new article adds another five "myths to bust".

Not that I agree, and confusing advice at best, but this is what a typical doctor might read about the value of reducing sugar for a Cancer patient.

Mythbusters: Complementary and Alternative Treatments in Cancer
http://www.medscape.com/viewarticle...ol&uac=186353HR

Quote:
Sugar-Free Diet

Proposition: Cutting sugar out of one's diet will stop a tumor from growing.

What the science says: After a cancer diagnosis, patients frequently ask their oncologist about the foods they should and shouldn't eat. A particularly common query is whether eliminating sugar will help starve tumor growth.

At a glance, the evidence appears quite compelling. Consuming copious amounts of sugar is associated with a slew of poor health outcomes, including diabetes, obesity, and cardiovascular disease. And studies have consistently shown a link between excess consumption of refined sugars and greater cancer risk as well as a rather robust relationship between being overweight or obese and an increased likelihood of developing cancer.[5,23]

One comprehensive review published in 2011 looked at whether reducing glucose consumption could help prevent or treat cancer.[24] Studies showed that when starved of glucose, tumor cells commit cell suicide in vitro, and that high glucose concentrations may alter gene expression in ways that promote cell growth in tumor cells studied in vitro. Still, there are no RCTs in humans that have evaluated whether sugar fuels cancer growth.

"It is true that when a cell becomes a cancer cell, it changes its cellular metabolism, and in a cell culture dish, a cancer cell prefers sugar," said Dr. Rock. "But in the context of the human body, cancer cells don't behave the same way, so we can't extrapolate from the cell culture to humans."

According to the 2012 ACS guidelines on nutrition and physical activity for cancer prevention, the best diet advice is to consume mostly fruits, vegetables, lean meats, low-fat dairy products, and whole grains and to limit the consumption of red and processed meats and alcohol as well as high-fat, high-calorie foods that may promote weight gain.[5] One study found that adhering to the ACS dietary guidelines was associated with lower mortality from cancer, cardiovascular diseases, and any cause.[25] This prospective study evaluated the effects of dietary patterns on the risk for cardiovascular, cancer, and all-cause mortality among 72,113 healthy women. After following these women for 18 years, the researchers determined that those who consumed a diet high in red and processed meats, refined grains, and desserts had a 16% greater risk of dying from cancer and a 21% greater risk of dying from any cause compared with those who followed a healthful diet of mostly vegetables, fruit, fish, poultry, and whole grains. Although the study did not separate out the effects of different foods on cancer mortality, it contributes to a growing body of literature that demonstrates that maintaining a generally healthy diet can decrease the risk of developing and dying from cancer.

What the experts say: "The sugar in your diet won't promote cancer growth, and there are no studies to date that show that avoiding sugar will shrink a tumor," said Dr. Rock. "Still, no oncologist or nutritionist would recommend a high-sugar diet because patients would be missing out on the beneficial nutrients."

But, Dr. Rock added, "When patients go through chemo- or radiation therapy, their tastes often change and they may lose weight. If putting sugar in food helps some patients get the vitamins and minerals they need, then eating sugar is not such a bad thing. Overall, though, it's best not to consume foods with added sugar or fat."

According to Dr. Deng, eating too much sugar is bad for us -- not just from a cancer standpoint but for many other health reasons. "Although we don't have evidence that eliminating refined sugar will shrink tumor and prolong survival, doing so is a low-risk lifestyle change and will certainly not harm patients. We are not talking about giving people a toxic drug, so there is very little downside." Still, Dr. Deng cautioned, "None of the radical anticancer diets that employ restrictive regimens have been shown to improve survival. The downside to such restrictive diets is that patients run the risk of depriving themselves of essential nutrients."

Verdict: Unconfirmed for a potential anticancer effect of eliminating sugar, but it's important to minimize excess sugar intake as part of maintaining a generally healthy diet.

Last edited by JEY100 : Sat, Mar-14-15 at 12:07.
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  #88   ^
Old Sat, Mar-14-15, 10:01
teaser's Avatar
teaser teaser is offline
Senior Member
Posts: 10,750
 
Plan: ketosis/IF
Stats: 190/158/154 Male 67inches
BF:
Progress: 89%
Location: Ontario
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Quote:
Although the study did not separate out the effects of different foods on cancer mortality, it contributes to a growing body of literature that demonstrates that maintaining a generally healthy diet can decrease the risk of developing and dying from cancer.


What it adds to is the growing body of literature that does not separate out the effects of different foods on cancer mortality--which is to say, it teaches us nothing new and is probably a massive waste of money.


Quote:
What the experts say: "The sugar in your diet won't promote cancer growth, and there are no studies to date that show that avoiding sugar will shrink a tumor,"


The red hasn't been established, and the rest of the sentence is partially true--we need studies to show whether a ketogenic diet will shrink tumours in humans. Back to the quackiness issue--before the effect of diet on various types of cancer in human beings has been established, it's just as quacky to promise that sugar won't promote cancer, as an absolute statement, as it is to promise that it will inhibit it.
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  #89   ^
Old Sat, Mar-14-15, 10:04
WereBear's Avatar
WereBear WereBear is offline
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Plan: Epi-Paleo/IF
Stats: 220/162/150 Female 67
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But there are studies that show ketogenic diets shrink brain tumors.
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  #90   ^
Old Sat, Mar-14-15, 12:23
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ojoj ojoj is offline
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Plan: atkins
Stats: 210/126/127 Female 5ft 7in
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Location: South of England
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Quote:
Originally Posted by teaser
What it adds to is the growing body of literature that does not separate out the effects of different foods on cancer mortality--which is to say, it teaches us nothing new and is probably a massive waste of money.




The red hasn't been established, and the rest of the sentence is partially true--we need studies to show whether a ketogenic diet will shrink tumours in humans. Back to the quackiness issue--before the effect of diet on various types of cancer in human beings has been established, it's just as quacky to promise that sugar won't promote cancer, as an absolute statement, as it is to promise that it will inhibit it.



I wonder if there is any correlation between the increase of sugar in our diets and the increase of cancer incidents ??

Jo xxx
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