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  #1   ^
Old Tue, Jul-27-10, 15:34
kilton kilton is offline
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Default Excessive Intake of Omega 6 and Deficiencies in Omega 3 Induce Obesity...

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  #2   ^
Old Tue, Jul-27-10, 17:46
Nancy LC's Avatar
Nancy LC Nancy LC is online now
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Plan: Hedonic Paleo
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Here's some relevant quotes.
Quote:
ScienceDaily (July 26, 2010) — Chronic excess of linoleic acid (omega 6), coupled with a deficiency in alpha-linoleic acid (omega 3), can increase obesity down the generations. This has been demonstrated for the first time by Gérard Ailhaud (Université de Nice-Sophia Antipolis) working in collaboration with three CNRS laboratories and one INRA laboratory. The researchers exposed several generations of male and female adult and young mice to a "Western-like" diet of this type, and then assessed the consequences of such a lipid environment in the human diet.


Quote:
To perform their experiments, the researchers exposed four generations of mice to a Western-style diet, characterized by these same omega 6/omega 3 ratios. As a result, they saw a gradual increase in fat mass over several generations. They also observed the onset of metabolic disorders such as insulin resistance, which is the first step in the development of type 2 diabetes and a stimulation of the expression of the inflammatory genes involved in obesity.

Thus, in a genetically-stable animal population, exposure to a diet similar to that of developed or developing countries was sufficient to cause the emergence of transgenerational obesity, in line with the data collected in humans. The beneficial role of essential polyunsaturated fatty acids such as omega 6 (linoleic acid) is well-known in the treatment of hypercholesterolemia, and that of omega 3 in cerebral function. But when their intake is unbalanced, these fatty acids can enhance the factors inducing obesity and have serious long-term effects on human health. The agrifood industry needs to take greater account of the implications of these findings.


I remember my Mom thinking safflower oil was the bees knees.
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  #3   ^
Old Tue, Jul-27-10, 18:38
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NewRuth NewRuth is offline
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It's a mouse study.

Mice are just not naturally big fat eaters.

I'm not going to worry about this one.
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  #4   ^
Old Wed, Jul-28-10, 03:07
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Hutchinson Hutchinson is online now
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Quote:
Originally Posted by NewRuth
It's a mouse study.

Mice are just not naturally big fat eaters.

I'm not going to worry about this one.
I think if you read the full text you may be more worried.
Stephan discussed this idea some time ago Have Seed Oils Caused a Multi-Generational Obesity Epidemic?

Here is a sample paragraph from the full text of the paper this article was based on.
Collectively, our data show that continuous exposure to a high-fat diet combined with a high LA:LNA ratio from fetal to adult age over generations triggers a discrete and steady increase in inflammatory stimuli accompanied by enhancement of fat mass that was already observed a few weeks after birth. Most interestingly, in humans, the recent Framingham Heart study pointed out that nonobese offspring with two obese parents had higher C-reactive protein levels compared with offspring with one or no obese parent. Thus offspring with a high risk of developing obesity are characterized at birth by a proinflammatory state.

Another worry they idendified was persistent dysregulation of insulin.
Strongly suggesting insulin resistance, consistent with progressive loss in sympathetic inhibition of insulin release over generations.
They suggest enhanced fat mass may be an adaptive response to prevent aggravation of metabolic syndrome.

Last edited by Hutchinson : Wed, Jul-28-10 at 03:29.
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  #5   ^
Old Wed, Jul-28-10, 09:11
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teaser teaser is offline
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Quote:
Omega 6 are normally found in maize, which is itself consumed in large quantities by the farmed animals eaten by humans (half of our lipid intake comes from meat and dairy products).

They imply that this makes dairy high in omega 6, but it doesn't. Chicken and porkfat might be a problem, but beef fat shouldn't be. Human consumption of seed oils isn't even mentioned in the article, although they make certain to list the plant sources of omega 3's ahead of the animal sources.
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  #6   ^
Old Wed, Jul-28-10, 09:55
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Hutchinson Hutchinson is online now
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Quote:
Originally Posted by teaser
They imply that this makes dairy high in omega 6, but it doesn't. Chicken and porkfat might be a problem, but beef fat shouldn't be. Human consumption of seed oils isn't even mentioned in the article, although they make certain to list the plant sources of omega 3's ahead of the animal sources.
However those are faults with the article and are not reflected in the full text of the paper on which the article is based.
they used LA (linoleic acid) represented 18% and (alpha-linolenic acid) LNA 0.6% of the total energy intake compared with 5–7% and 0.8–1%, respectively, recommended for humans by expert committees on nutrition. Unfortunately, a significantly higher LA intake and much lower LNA intake are frequently observed in most industrialized countries.
Unfortunately I haven't got the supplementary table showing the make up of the chow used.
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  #7   ^
Old Wed, Jul-28-10, 13:16
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Hutchinson Hutchinson is online now
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Food for Thought: "Omega-3s" and the Brain

We don't eat like hunter gatherers anymore - trans-fatty, processed foods long ago displaced wild plants and animals. But have changes in the types of fat we eat affected both our physical and mental health? We discuss why omega-3 fatty acids may be the true "good mood food."

Guests

Joseph Hibbeln
Lead clinical investigator, Nutrition in Psychiatry Unit, NIH; Commander, U.S. Public Health Service
J. Thomas Brenna
Professor of Nutritional Sciences, Cornell University
Evelyn Tribole
Registered Dietitian; Nutritional Counselor; Author, "The Ultimate Omega-3 Diet" (McGraw-Hill)
Useful radio program setting out the basics of omega 3 omega 6 for anyone who needs to catch up.
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