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  #1   ^
Old Sun, Jul-18-10, 09:05
Nancy LC's Avatar
Nancy LC Nancy LC is online now
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Plan: Hedonic Paleo
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Default Feeding brain cancer

Interesting article about brain cancer and ketogenic diet.

]Does the Existing Standard of Care Supply Energy Sources to Brain Tumor Cells?

Quote:
"All tumors, regardless of where they are located, require two major fuels for survival: glucose and glutamine," said Seyfried, a specialist in lipid biochemistry. "As long as tumor cells have access to these energy molecules, they will survive. If you give them a lot of these molecules, they will survive even better."

...

Seyfried says this "perfect storm" of side-effects from the standard of care for glioblastoma should invite a broader discussion among researchers for potential alternative therapies. Through his past research, Seyfried has detailed the benefits of non-toxic metabolic therapies involving ketogenic diets that effectively restrict glucose-based fuels to brain tumors. By regulating glucose availability while simultaneously elevating fat-derived ketone bodies, which brain tumors cannot actively use for growth or survival, the ketogenic diet has been shown to control epileptic seizures, but there have been no human trials to test its therapeutic efficacy against brain cancer.

You can't really avoid the glutamine but the glucose is something that can be controlled (with limits).
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  #2   ^
Old Sun, Jul-18-10, 09:44
sln88 sln88 is offline
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Plan: ZC/VLC
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I sometimes take L-glutamine for sugar cravings. Is this bad?
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  #3   ^
Old Sun, Jul-18-10, 10:15
Nancy LC's Avatar
Nancy LC Nancy LC is online now
Posts: 30,453
 
Plan: Hedonic Paleo
Stats: 209.5/170.4/165 Female 5'8"
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Location: San Diego, CA
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You can't really avoid glutamine. It's an amino acid and found in almost everything you eat. I suppose it would be unwise to take it if you have brain cancer.
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  #4   ^
Old Sun, Jul-18-10, 10:59
sln88 sln88 is offline
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makes me nervous as my sister died of a brain tumor.
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  #5   ^
Old Sun, Jul-18-10, 12:16
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Hutchinson Hutchinson is online now
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  #6   ^
Old Sun, Jul-18-10, 14:56
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Kisal Kisal is offline
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Thank you for those links, Hutchinson. I needed to know the information contained in the articles.
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  #7   ^
Old Sun, Jul-18-10, 17:16
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WereBear WereBear is offline
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Plan: Atkins, a bit Paleo
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I'm very pleased to hear this, since there was a long ago study. Two young people tried it for brain cancer when all else failed. One, it didn't seem to help. The other, I found out recently, is supposedly still alive. Some 20 years later.
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  #8   ^
Old Sun, Jul-18-10, 17:38
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AnniMin AnniMin is offline
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This is interesting. When my husband had cancer his oncologist said sugar had nothing to do with feeding the cancer and the dieticians told him to eat anything he could get down, even if it was cake and ice cream. He lived for several months on nothing but Ensure, and that's full of sugar. Fortunately he survived the cancer and the horrible treatments he went through to cure it.
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  #9   ^
Old Wed, Jul-21-10, 16:17
WereBear's Avatar
WereBear WereBear is offline
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Plan: Atkins, a bit Paleo
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I'm so glad to hear that, Anni!

I had a cancer scare; and my googling on what doctors said to each other convinced me that chemo would be a very bad bet. I was going to try the ketogenic method. Fortunately, it didn't come to that; but I was serious.
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  #10   ^
Old Wed, Jul-21-10, 19:58
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steakum steakum is offline
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thanks for the links.
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  #11   ^
Old Sat, Jul-24-10, 16:04
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Voo36 Voo36 is offline
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From personal observations of 2 cancer patients - both would eat only sugary foods. My theory is the cancer thrives on sugar and was literally demanding to be fed.

When my research turned up that cancer thrived on glucose, I put my ex on a high protein lc diet with no sugar. He's still living nearly 10 years after being diagnosed, despite being given only a 10% chance of surviving 2 years.

The other young man had parents who could not deny their son any pleasure, no matter how small, so his diet consisted of favorite junk food and sweets. Unfortunately his cancer ran rampant and he died within 7 mos of being diagnosed.

Sure do wish they would devote more research to the effects of starving cancer of nutrients while still supporting the body with a sugar free / LC diet.
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  #12   ^
Old Sat, Jul-24-10, 16:29
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Wifezilla Wifezilla is offline
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Plan: I'm a Barry Girl
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There was a trial (or is one...not sure if it is done) in Germany. I vaguely remember some preliminary info being reported in one of the journals and it looked good.

The problem they were having though is the government would only let them test on people that were so far gone they were mostly toast anyway.

Hopefully someone who actually remembers the journal report will stumble by.
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