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  #16   ^
Old Tue, Mar-06-07, 17:14
Dodger's Avatar
Dodger Dodger is offline
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Here is the abstract from the Journal.

Comparison of the Atkins, Zone, Ornish, and LEARN Diets for Change in Weight and Related Risk Factors Among Overweight Premenopausal Women
The A TO Z Weight Loss Study: A Randomized Trial

Christopher D. Gardner, PhD; Alexandre Kiazand, MD; Sofiya Alhassan, PhD; Soowon Kim, PhD; Randall S. Stafford, MD, PhD; Raymond R. Balise, PhD; Helena C. Kraemer, PhD; Abby C. King, PhD


JAMA. 2007;297:969-977.

Context Popular diets, particularly those low in carbohydrates, have challenged current recommendations advising a low-fat, high-carbohydrate diet for weight loss. Potential benefits and risks have not been tested adequately.

Objective To compare 4 weight-loss diets representing a spectrum of low to high carbohydrate intake for effects on weight loss and related metabolic variables.

Design, Setting, and Participants Twelve-month randomized trial conducted in the United States from February 2003 to October 2005 among 311 free-living, overweight/obese (body mass index, 27-40) nondiabetic, premenopausal women.

Intervention Participants were randomly assigned to follow the Atkins (n = 77), Zone (n = 79), LEARN (n = 79), or Ornish (n = 76) diets and received weekly instruction for 2 months, then an additional 10-month follow-up.

Main Outcome Measures Weight loss at 12 months was the primary outcome. Secondary outcomes included lipid profile (low-density lipoprotein, high-density lipoprotein, and non–high-density lipoprotein cholesterol, and triglyceride levels), percentage of body fat, waist-hip ratio, fasting insulin and glucose levels, and blood pressure. Outcomes were assessed at months 0, 2, 6, and 12. The Tukey studentized range test was used to adjust for multiple testing.

Results Weight loss was greater for women in the Atkins diet group compared with the other diet groups at 12 months, and mean 12-month weight loss was significantly different between the Atkins and Zone diets (P<.05). Mean 12-month weight loss was as follows: Atkins, –4.7 kg (95% confidence interval [CI], –6.3 to –3.1 kg), Zone, –1.6 kg (95% CI, –2.8 to –0.4 kg), LEARN, –2.6 kg (–3.8 to –1.3 kg), and Ornish, –2.2 kg (–3.6 to –0.8 kg). Weight loss was not statistically different among the Zone, LEARN, and Ornish groups. At 12 months, secondary outcomes for the Atkins group were comparable with or more favorable than the other diet groups.

Conclusions In this study, premenopausal overweight and obese women assigned to follow the Atkins diet, which had the lowest carbohydrate intake, lost more weight and experienced more favorable overall metabolic effects at 12 months than women assigned to follow the Zone, Ornish, or LEARN diets. While questions remain about long-term effects and mechanisms, a low-carbohydrate, high-protein, high-fat diet may be considered a feasible alternative recommendation for weight loss.

Trial Registration clinicaltrials.gov Identifier: NCT00079573


Author Affiliations: Stanford Prevention Research Center and the Department of Medicine, Stanford University Medical School, Stanford, Calif.
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  #17   ^
Old Tue, Mar-06-07, 18:16
pbowers's Avatar
pbowers pbowers is offline
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i put the article here .
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  #18   ^
Old Tue, Mar-06-07, 20:14
Samuel Samuel is offline
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Default Study tips scale in favor of Atkins diet

Study tips scale in favor of Atkins diet

Reuters

March 06, 2007



Many health professionals, including us, have either dismissed the value of very-low-carbohydrate diets for weight loss or been very skeptical of them


By Michael Conlon

CHICAGO (Reuters) - A study of four popular diets found that women put on the one with the least carbohydrates -- the Atkins plan -- lost at least twice as much weight as those on the others, researchers said on Tuesday.

"Many health professionals, including us, have either dismissed the value of very-low-carbohydrate diets for weight loss or been very skeptical of them," said Christopher Gardner, assistant professor of medicine at the Stanford Prevention Research Center in California, lead author of the study.

"But it seems to be a viable alternative for dieters," he added, for whom the basic message is cutting down as much as possible on refined carbohydrates such as white bread and soda.

The research was described as the largest and longest comparison yet done on the four diets.

They were Atkins, the lowest in carbohydrates for the four; the Zone diet, also low in carbohydrates and based on a 40:30:30 ratio of carbohydrates to protein to fat; the Lifestyle, Exercise, Attitudes, Relationships and Nutrition (LEARN) diet which follows U.S. government guidelines for low fat but higher carbohydrates; and the Ornish diet, which is very high in carbohydrates but very low in fat.

The study randomly assigned a group of 311 overweight, post-menopausal, non-diabetic women one of the four diets. All attended weekly diet classes for eight weeks and were given books to follow. Their weight and metabolism were then checked for the following 10 months.

CHOLESTEROL AND BLOOD PRESSURE

Women assigned to the Atkins group lost an average of 10.4 pounds (4.7 kg) compared to 5.7 pounds (2.5 kg) for LEARN, 4.8 pounds (2.1 kg) for Ornish and 3.5 pounds (1.6 kg) for Zone, the study said.

The women on the Atkins diet also had the most improvements in terms of cholesterol and blood pressure, added the study published in this week's Journal of the American Medical Association.

The authors said some have worried that diets low in carbohydrates but high in total and saturated fat would cause cholesterol problems and increase the risk of heart disease.

"These concerns have not been substantiated in recent weight-loss diet trials," including the new research, the authors said.

Barry Sears, who developed the Zone diet, criticized the study as "bad science," saying details show the participants did not really follow the diet rules.

"The execution basically was fairly pathetic at best so the conclusions are jaded," he said in an interview. The way people followed the Atkins diet in the study, he said, is actually closer to the Zone's principles.

Study author Gardner, however, said one of the strengths of the $2 million project was that it mimicked real-world conditions, with participants preparing or buying all their own meals and not everyone following the diets exactly.

Gardner said the Atkins diet has "a very simple message. Get rid of all refined carbohydrates to lose weight," thus targeting the increasing consumption of refined sugars, such as high-fructose corn syrup.

He also said the Atkins diet is best at encouraging people to drink more water, and when people replace sweetened drinks with water, they do not generally eat more
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  #19   ^
Old Tue, Mar-06-07, 20:20
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elpasopop elpasopop is offline
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Quote:
Originally Posted by Samuel
I believe that there is a cause for the current obesity epidemic and that there will be no permanent cure for obesity untill that cause is discovered. However, I agree that Atkins diet is the only diet which can stabilize your weight with minimum suffering until that cure is found.


Unfortunately, in contradistinction to what some in Atkins-land espouse, the cause of obesity is eating more calories than you burn. Period, end of story. Now, the reasons for eating more calories than we burn are multicausal, but we can probably start with affluence, sedentary lifestyles, fast food in poor neighborhoods, loss of PE in schools, poor dietary choices made by working adults, advertising, and addicition/emotional disorders, to name a few. Fix those problems and the Nobel is yours. Shoot, the world is yours.

The "permanent cure" is to eat less calories than one needs to maintain current body weight. Which, during the past 60 days of working the Atkins program, I have been able to achieve. It's the best metabolic advantage one can have.

Glad this article is coming out, it is another tool in the toolbox for physicians.
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  #20   ^
Old Tue, Mar-06-07, 20:24
Samuel Samuel is offline
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Default Study: Atkins Doesn't Raise BP, Cholesterol

http://www.nbc30.com/news/11185197/detail.html

Study: Atkins Doesn't Raise BP, Cholesterol
Some Worry About Fat, Cholesterol In Low-Carb Diet
POSTED: 3:58 pm EST March 6, 2007


The Atkins diet is a very popular way to lose weight. But the idea of cutting carbohydrates and eating more protein and fat worries some doctors, who fear it could lead to increased cholesterol and blood pressure.

A new study in the Journal of the American Medical Association shows that not only was Atkins the most successful of four diets at weight loss, but that it did not increase blood pressure or cholesterol.

Christine Dillion said the diet worked for her.


"I was on the Atkins diet for about nine months and lost between 10 and 15 pounds but, much more importantly, lost two dress sizes, which is huge," she said.

Her results were typical in the study by Christopher Gardner, of Stanford University, that compared Atkins to the Zone, Learn and Ornish diets in about 300 women.

"By the end of the year, on average within the Atkins group, the average woman lost 10 pounds compared to the other three groups, where the average loss was closer to 5 pounds," he said.

Gardner said the simplicity of the diet may be the key to its success.

"Cutting out those simple refined carbohydrates -- the white bread, the white rice, the high fructose corn syrup, the soda pop," he said.

People on Atkins replaced soda with water, and Gardner said that played a big role in weight loss. A heart disease specialist who helped the study, Dr. Randall Stafford, agreed.

"This study will change my practices. In the future, I'm going to be more supportive of patients who come in already on an Atkins diet, and I'm certainly going to suggest this as a possible, reasonable approach to weight loss," he said.

The study's authors stressed that if people are going to go on the Atkins diet, they should follow the actual diet, which includes all kinds of healthy proteins, not just those that are high in fat and cholesterol.
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  #21   ^
Old Tue, Mar-06-07, 20:28
elpasopop's Avatar
elpasopop elpasopop is offline
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Quote:
Originally Posted by Dodger
The problem that I have with studies like this is the randomization of the diets. People are randomly assigned to one of the diets. This tends to cause poor compliance. Many people have heard so much about the harmful effects of eating fat that, if assigned to Atkins, they try to eat low-carb and low-fat. This ends up being too few calories and leads to binges and going off the plan. It would be even worse for those randomly assigned to Ornish. You really have to be a fanatic to keep on that plan.

I would much rather have the people choose which plan they want to go on. Of course this would make it difficult to fill out some of the groups.


Problem is, without randomization you can't use analytical methods (in this case epidemiological analyses) to draw inferences. In order to convince the scientific establishment of anything, we must use their language and processes to compare our apples to their apples. We know anecdotally that Atkins works, but that and a dollar will get you a non-Starbucks coffee at a scientific symposium of dietitians and bariatric docs.
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  #22   ^
Old Tue, Mar-06-07, 20:47
CarolynC's Avatar
CarolynC CarolynC is offline
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An article linked on the front page of today's USA Today online also says that Atkins beats other diet plans in a study. See:

http://www.usatoday.com/news/health...kins-diet_N.htm
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  #23   ^
Old Tue, Mar-06-07, 20:55
Samuel Samuel is offline
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Quote:
Originally Posted by elpasopop
Unfortunately, in contradistinction to what some in Atkins-land espouse, the cause of obesity is eating more calories than you burn. Period, end of story.

Sorry, although I agree that eating more calories than you burn is the direct cause, but we can't end the story here.

The human body contains a self regulation mechanism which - if functioning properly - knows how to maintain a constant weight. You cannot eat unless your body allows you to. Even if you could force yourself to eat and keep doing that for a long time, your body have other means to stabilize your weight. It can raise your metabolic rate, it pass food without complete digestion and it can even make you thraw-up if necessary.

Last edited by Samuel : Tue, Mar-06-07 at 21:24.
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  #24   ^
Old Tue, Mar-06-07, 20:58
pbowers's Avatar
pbowers pbowers is offline
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it didn't take long. the spin doctors have already started spinning and whinning and outright lying. ornish, of course, has the most spinning to do, because he's also defending the animals that the atkins people call breakfast lunch and dinner. sears and brownell are already on damage control as well.


Ornish: Why I Disagree With New Diet Study
A new comparison of four diets—including mine—is misleading and riddled with problems.
By Dean Ornish, M.D.
Special to Newsweek
Updated: 7:29 p.m. ET March 6, 2007

March 6, 2007 - A study came out today in the Journal of the American Medical Association (JAMA) claiming that you can lose more weight on an Atkins diet than an Ornish, Zone, or LEARN (Lifestyle, Exercise, Attitudes, Relationships and Nutrition) diet and—ta dah!—(drum roll, maestro), it’s even better for your heart! I imagine that a lot of people are going to be saying, “You mean I’ve been eating fruits and vegetables for all these years for nothing when I could have been eating bacon and eggs? What was I thinking!”

The authors concluded, “Women assigned to follow the Atkins diet, which had the lowest carbohydrate intake, lost more weight and experienced more favorable overall metabolic effects at 12 months than those assigned to follow the Zone, Ornish, or LEARN diets.” This is simply not true. If you read the study carefully, you will find that the authors found that there was no significant difference in weight loss between the Atkins and Ornish or LEARN diets after one year! (There was significantly more weight loss on the Atkins diet after one year only when compared with the Zone diet.) This directly contradicts the primary conclusion of their study.

As a result, many people may go on a diet that harms them based on inaccurate information. Other studies also found that people who lost weight on an Atkins diet after six months gained it back after one year.

This new JAMA study is seriously flawed and its conclusions misleading for other reasons. Here’s why:
# Most study participants weren’t following an Ornish diet, which is 10 percent fat. They reduced their fat intake from an average of 35 percent to only 30 percent after one year. If they’re not following the dietary recommendations, it’s not surprising that they didn’t show as much improvement. By analogy, two-thirds of people prescribed Lipitor aren’t taking it only four months later. Lipitor is a very effective way to lower cholesterol levels, but only if you take it. It would have been helpful if the authors had reported findings on the subset of people who actually followed the different diets to see what happened to them.

# When people adhere to an Ornish diet, they have striking improvements. In a randomized controlled trial, also published in JAMA, study participants who were asked to follow an Ornish diet showed a 25 pound weight loss after one year and kept off half that weight five years later. Also, they had a 40 percent average decrease in LDL-cholesterol without cholesterol-lowering drugs, and their apolipoprotein profiles improved. In a series of randomized controlled trials, patients showed some reversal of coronary heart disease after only one month, even more after one year, and even more after five years using state-of-the-art measures such as quantitative coronary arteriography and cardiac PET scans, also published in JAMA.

There was a direct correlation between how well people adhered to the diet and how much blockage there was in their coronary arteries. There were 2.5 times fewer cardiac events such as heart attacks, and 99 percent of these patients stopped or reversed the progression of their heart disease. These are actual measures of heart disease, not just risk factors such as changes in cholesterol levels. So, for the study that came out today in JAMA to say that the Atkins diet is just as good for your heart as an Ornish diet makes me a little crazy, since they didn’t measure heart disease, only risk factors.

Last year, my colleagues and I at the nonprofit Preventive Medicine Research Institute and the University of California, San Francisco published the first randomized controlled trial showing that our diet and lifestyle program could stop or reverse the progression of prostate cancer. We also found this diet may reverse the progression of diabetes, high blood pressure, and other chronic diseases.

# In contrast, studies show that heart disease worsens on the Atkins diet. This is consistent with published autopsy results on Dr. Atkins revealing that he had serious heart disease when he died. It’s important to lose weight in a way that enhances health rather than ones that may harm it. These are summarized more extensively in a review article that I wrote, “Was Dr. Atkins Right?” that was published in the Journal of the American Dietetic Association.

# LDL (“bad” cholesterol) rose on the Atkins diet but came down on the Ornish diet in this new JAMA study.

# HDL (“good cholesterol”) rose slightly on the Atkins diet but did not change after one year on the Ornish diet. However, not everything that raises HDL is good, which is summarized in a recent NEWSWEEK column, “The Garbage Trucks in Your Blood.” Your body makes HDL to get rid of excessive saturated fat and cholesterol in your diet. If you eat a stick of butter, your HDL will go up, but that doesn’t mean that butter is good for your heart. Pfizer recently had to stop a large trial of torcetrapib when it was found that this drug raised HDL but also increased the risk of heart attacks and strokes.

# This study did not test the effectiveness of different diets. It only tested how well people adhered to different diets simply by reading a book and having a few sessions with a dietitian. It’s easier for people to follow an Atkins diet of bacon and brie than an Ornish diet that includes fruits, vegetables, whole grains, legumes, soy products, and fish, so it’s not surprising that people adhered better to an Atkins diet. However, we need to distinguish what is healthful from what is easy. I’d love to be able to tell you that bacon and brie are good for your heart, but they’re not. Enjoy them in moderation, if you wish, but don’t kid yourself that these are health foods. Also, the diet is only one component of my lifestyle program. It’s hard to adhere to a new way of eating unless you also practice stress management techniques and have psychosocial support, since many people overeat when they are under stress or feeling lonely and depressed.

# Given sufficient support, many people are able to follow our program of diet and lifestyle changes. Beginning in 1993, my colleagues and I at the nonprofit Preventive Medicine Research Institute began training hospitals in our diet and lifestyle program at hospitals throughout the country. Not just in San Francisco, Boston, and New York, but also in Columbia, SC, where they told me, “gravy is a beverage,” as well as 10 hospitals in West Virginia, which is No. 1 in the country in the incidence of heart disease. We now have data from more than 3,000 patients who have gone through our program in three demonstration projects, including one with Medicare. We have consistently found bigger changes in diet and lifestyle, better clinical outcomes, and larger cost savings than have ever before been documented.

# Medicare recently agreed to cover our program for reversing heart disease. Two years ago, we presented data from the first 2,000 patients to the Medicare Coverage Advisory Commission in an all-day hearing. These patients lost almost 20 pounds during the first year, their blood pressure decreased from 150/86 to 129/76, and their fasting blood sugar decreased from 150 to 125 mg/dl.

Having spent the past 30 years of my life conducting research showing what a powerful difference changes in diet and lifestyle can make, I’m concerned that this study may cause some people to forego eating a healthy diet in favor of one that may be harmful to them. I’m tired of these diet wars. It’s not low fat vs. low carb. It’s both. An optimal diet is low in total fat and low in refined carbohydrates, emphasizing whole foods such as fruits, vegetables, and whole grains.

http://www.msnbc.msn.com/id/1749014...ewsweek/page/2/
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  #25   ^
Old Tue, Mar-06-07, 21:22
Samuel Samuel is offline
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Actually, this means good news to us. The concerns of Ornish and Sears mean that the new study can cause a change in how Atkins diet is evaluated by the medical community.
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  #26   ^
Old Wed, Mar-07-07, 03:50
Demi's Avatar
Demi Demi is offline
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This study has also now been reported by New Scientist:

Atkins diet marginally better than rivals


The Times Online site has changed the front page link to the original story to read: Atkins is a girl's best friend ... if one phrase is guaranteed to revive the Atkins diet in the UK, then that's definitely it! (Sorry guys!)
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  #27   ^
Old Wed, Mar-07-07, 03:54
Demi's Avatar
Demi Demi is offline
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Have also just come across these:

Atkins Fares Best in Study Of Four Weight-Loss Regimens - Washington Post

Atkins Beats Other Diet Plans in Study - Associated Press (Published in Washington Post)

Eat To Live: Atkins diet back on top - Science News Daily


I know that these articles are all much of a muchness, but IMO it's good to see the Atkins (low carb) message being given positive publicity in this way.

Last edited by Demi : Wed, Mar-07-07 at 04:32.
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  #28   ^
Old Wed, Mar-07-07, 04:17
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Nico78 Nico78 is offline
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This is the link

http://www.newscientist.com/article...line-news_rss20

It says that Atkins is marginally better than rivals diets.... but I really don't understand all the reasoning they did just to say that in the end we are eating low-calories and that's still the reason we are losing weight.
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  #29   ^
Old Wed, Mar-07-07, 04:32
kebaldwin kebaldwin is offline
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Quote:
Originally Posted by elpasopop
Unfortunately, in contradistinction to what some in Atkins-land espouse, the cause of obesity is eating more calories than you burn. Period, end of story.


You are incorrect. Millions of Atkins dieters have proved that incorrect. I hope that you soon start listening.
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  #30   ^
Old Wed, Mar-07-07, 05:21
kneebrace kneebrace is offline
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Quote:
Originally Posted by elpasopop
Unfortunately, in contradistinction to what some in Atkins-land espouse, the cause of obesity is eating more calories than you burn. Period, end of story.


Actually it's only the beginning of the story elpasopop. Firstly because a low carb dietary approach will also cause a human body to burn more calories per calorie consumed. And secondly, and IMHO far more importantly, the hormonal environment engendered by low carb will lead to many of the 'excess to energy demands' calories consumed being merely excreted. I wish more bench scientists would start analyzing the energy content of human urine under different macronutrient ratios. It seems a pretty obvious place to start looking for the explanation of why 'eating more calories than you burn' is a hopelessly simplistic and inadequate explanation of obesity.... or the lack of it
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