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  #1   ^
Old Thu, Apr-13-06, 19:58
Dodger's Avatar
Dodger Dodger is offline
Posts: 8,765
 
Plan: Paleoish/Keto
Stats: 225/167/175 Male 71.5 inches
BF:18%
Progress: 116%
Location: Longmont, Colorado
Default Lowering LDL and Total Cholesterol Does Not Reduce Heart Risk

While I doubt you will ever see the headline above in a news article, it is the conclusion that can be drawn from the recently concluded (results announced today) RUTH study.

From http://www.medadnews.com/News/index...rticleid=330933

Quote:
The study included more than 10,000 women from 26 countries who were followed for up to seven years. All women enrolled in RUTH had known heart disease or were at high risk for heart attack.

Primary Endpoint Findings

Preliminary analyses of the study's two primary endpoints indicate:

-- EVISTA did not increase or decrease the combined endpoint of non-fatal heart attack, fatal heart attack, and hospitalized acute coronary syndrome compared to placebo.

As Evista is a drug for osteoporosis, why did Eli Lily do a seven year test on 10,000 people at risk for heart problems? Because Evista was found to lower LDL and total cholesterol in previous studies. And as all heart specialists 'know', lowering total and LDL reduces heart problems. While Lily has removed the information from their website, I found their old page in Google's cache.

Quote:
EVISTA also...
  • Lowers cholesterol. EVISTA lowers total cholesterol by about 7% and LDL (bad) cholesterol by about 11%. It does not change HDL (good) cholesterol. The effect of EVISTA on risk for cardiovascular events is currently under study.
The medical community will never put one and one together to get two and relalize that the RUTH study is further proof that lowering cholesterol (even the 'bad' LDL cholesterol) is not the way to defeat heart problems.
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  #2   ^
Old Thu, Apr-13-06, 20:05
JL53563's Avatar
JL53563 JL53563 is offline
Senior Member
Posts: 1,209
 
Plan: The Real Human Diet
Stats: 225/165/180 Male 5'8"
BF:?/?/8.6%
Progress: 133%
Location: Wisconsin, USA
Default

Good work, Dodger.
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  #3   ^
Old Thu, Apr-13-06, 20:45
Whoa182's Avatar
Whoa182 Whoa182 is offline
Registered Member
Posts: 1,770
 
Plan: CRON / Zone
Stats: 118/110/110 Male 5ft 7"
BF:very low
Progress: 100%
Location: Cardiff
Default

Interesting

I increased my Fat intake from 20% to 30% a few months ago, not long after I had my current lipids checked. hope I see my HDL go higher than LDL
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  #4   ^
Old Fri, Apr-14-06, 08:44
Nancy LC's Avatar
Nancy LC Nancy LC is offline
Experimenter
Posts: 25,865
 
Plan: DDF
Stats: 202/185.4/179 Female 67
BF:
Progress: 72%
Location: San Diego, CA
Default

Whoa, I'll be interested to see what it does for you!
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  #5   ^
Old Fri, Apr-14-06, 12:40
Wyvrn's Avatar
Wyvrn Wyvrn is offline
Dog is my copilot
Posts: 1,448
 
Plan: paleo/lowcarb
Stats: 210/162/145 Female 62in
BF:
Progress: 74%
Location: Olympia, WA
Default

Whoa, don't go too crazy with that... not all LDL is "bad". Do your tests come with the VLDL fraction broken out?

Wyv
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  #6   ^
Old Sun, Apr-16-06, 13:43
LC FP LC FP is offline
Senior Member
Posts: 1,162
 
Plan: Atkins
Stats: 228/195/188 Male 72 inches
BF:
Progress: 83%
Location: Erie PA
Default

Dodger, you're the best. I'm giving this to my cardiologist friends.
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