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  #1   ^
Old Tue, May-31-05, 17:23
Ironjustic
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Default Asthma / allergies / erythrocytosis / increased red blood cells

I suppose if one were to attempt to followup on the link
between increased blood cell mass / erythrocytosis .. one
might find a link then between INCREASED leukemia /
uncontrolled red blood cell production .. and asthma /
allergies .. ?

Voila ..

BMC Public Health. 2004 Nov 4;4(1):51. Related Articles, Links

Allergic conditions and risk of hematological malignancies in
adults: a cohort study.

Soderberg KC, Hagmar L, Schwartzbaum J, Feychting M.

The Institute of Environmental Medicine, Karolinska
Institutet, Box 210, S-171 77 Stockholm, Sweden.
Karin.Soderberg~imm.ki.se

BACKGROUND: Two contradictory hypotheses have been proposed to
explain the relationship between allergic conditions and
malignancies, the immune surveillance hypothesis and the
antigenic stimulation hypothesis. The former advocates that
allergic conditions may be protective against development of
cancer, whereas the latter proposes an increased risk. This
relationship has been studied in several case-control studies,
but only in a few cohort studies. METHODS: The association
between allergic conditions and risk of developing leukemia,
Hodgkin's disease, non-Hodgkin's lymphoma and myeloma was
investigated in a cohort of 16,539 Swedish twins born
1886-1925. Prospectively collected, self-reported information
about allergic conditions such as asthma, hay fever or eczema
was obtained through questionnaires administered in 1967. The
cohort was followed 1969-99 and cancer incidence was
ascertained from the Swedish Cancer Registry. RESULTS: Hives
and asthma tended to increase the risk of leukemia (relative
risk [RR] = 2.1, 95% Confidence Interval [CI] 1.0-4.5 and RR
= 1.6, 95% CI 0.8-3.5, respectively). There was also an
= indication of
an increased risk of non-Hodgkin's lymphoma associated with
eczema during childhood (RR = 2.3, 95% CI 1.0-5.3).
CONCLUSION: In contrast to most previous studies, our results
do not indicate a protective effect of allergic conditions on
the risk of developing hematological malignancies. Rather,
they suggest that allergic conditions might increase the risk
of some hematological malignancies.

Publication Types: Twin Study

PMID: 15527506 [PubMed - indexed for MEDLINE]

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  #2   ^
Old Tue, May-31-05, 17:23
Ironjustir
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Default Re: Asthma / allergies / erythrocytosis / increased red blood cells

ironjustice~aol.com wrote:
  > I suppose if one were to attempt to followup on the link
  > between increased blood cell mass / erythrocytosis .. one
  > might find a link then between INCREASED leukemia /
  > uncontrolled red blood cell production .. and asthma /
  > allergies .. ?
  >
  > Voila ..

Voila, as in "how wrong can you get"?

Neither leukemia nor myleloma present with increased blood
cell mass/ erythrocytosis. In fact, one of the diagnostic
hallmarks of these malignancies is anemia. How .. does .. that
.. make .. you .. feel?

Irrelevant (what else is new?) study snipped...
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  #3   ^
Old Wed, Jun-01-05, 06:17
Ironjustic
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Default Re: Asthma / allergies / erythrocytosis / increased red blood cells

Mr.. manwithasthma is NOW .. a .. cancer .. specialist ..

Jeez .. your abilities .. extend far beyond .. asthma ..

Eh ..

For .. sure ..

Heh .. heh ..

Stick .. to .. asthma ..

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  #4   ^
Old Wed, Jun-01-05, 06:17
Ironjustic
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Default Re: Asthma / allergies / erythrocytosis / increased red blood cells

Excuse .. me .. ?

Are you .. stupid .. ?

You must .. BE .. stupid ..

Another NAME .. for .. hemochromatosis .. IS ..
erythrocytosis ..

Iron overload = erythrocytosis .. ask any blood donor clinic
..

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  #5   ^
Old Wed, Jun-01-05, 06:17
Ironjustic
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Default Re: Asthma / allergies / erythrocytosis / increased red blood cells

  >The snip from a blood donor site below verifies this in
  >that it calls
hemochromatosis / iron overload as a 'category' .. OF ..
erythrocytosis .=2E too many red blood cells which leads to
hypervolemia ..

http://www.sfbb.org/can_I_don.=ADhtm

<<snip>> Hemochromatosis You may be eligible to donate blood
for others if you have hemochromatosis. To do so you must
present an appropriately completed prescription from your
physician. You must meet all other criteria for volunteer
whole blood donation other than the donation interval.* Other
categories* of erythrocytosis (too many red blood cells) such
as polycythemia vera will remain as therapeutic phlebotomies
per Food and Drug Administration (FDA) regulations. You can
contact South Florida Blood Banks, Inc. for further details at
our toll free number: 888 - 884 - LIFE <<snip>>

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  #6   ^
Old Wed, Jun-01-05, 06:17
Ironjustic
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Default Re: Asthma / allergies / erythrocytosis / increased red blood cells

Bone .. up .. boy ..

http://community.dadeschools.net/Bloodfaq.htm

     >>snip<<
Hemochromatosis You may be eligible to donate blood for
others if you have hemochromatosis. To do so you must present
an appropriately completed prescription from your physician.
You must meet all other criteria for volunteer whole blood
donation other than the donation interval. Other categories
of erythrocytosis (too many red blood cells) such as
polycythemia vera will remain as therapeutic phlebotomies per
Food and Drug Administration (FDA) regulations.
     >>snip<<

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  #7   ^
Old Wed, Jun-01-05, 06:17
Ironjustic
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Default Re: Asthma / allergies / erythrocytosis / increased red blood cells

Well .. YOU .. explain .. then ..

If you are . sooooo .. wise ..

WHY .. did I .. post this on both leukemia lists and asthma ..
lists .. ?

WHY .. ?

Pretty .. simple ..

And IF .. you .. DO .. 'know' .. WHY .. then .. why .. didn't
YOU .. enlighten .. your .. bro .. ARoberts .. ?

Eh .. ?

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  #8   ^
Old Wed, Jun-01-05, 06:17
Ironjustic
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Default Re: Asthma / allergies / erythrocytosis / increased red blood cells

Think of a tachometer of your car .. the red line .. is ..
leukemia .. death ..

Korean J Intern Med. 2004 Dec;19(4):285-8. Related
Articles, Links

A case of transition of polycythemia vera to chronic
neutrophilic leukemia.

Lee SS, Moon JH, Ha JW, Lee YK, Ahn JS, Zang DY, Kim HJ.

Department of Internal Medicine, College of Medicine, Hallym
University, Sacred Heart Hospital, Anyang, Korea.

Chronic Neutrophilic Leukemia (CNL) is a rare
myeloproliferative disorder characterized by a persistent
increase of mature peripheral neutrophils, myeloid hyperplasia
in bone marrow, hepatosplenomegaly, elevated neutrophil
alkaline phosphatase (NAP) and absence of Philadelphia
chromosome, with no evidence of infection or malignancy
sufficient to mimic a leukemoid reaction. CNL has been
associated with multiple myelomas in many reported cases, but
transition of Polycythemia Vera (PV) to CNL is very rare. An
81-year-old female patient, who had undergone intermittent
phlebotomy following the diagnosis of PV 8 years previously,
was admitted to our hospital due to lower back pain. A
physical examination showed a splenomegaly 2 cm below the
costal margin, with tenderness of the thoracic and lumbar
spine area. A peripheral blood examination showed a WBC count
of 91,800/microL (neutrophil 88%) with a rare immature form,
hemoglobin of
9.1 g/dL and a platelet count of 1,661,000/microL. Her
NAP score was
10. The bone marrow examination showed 95% cellularity, with
an M:E ratio of 10:1, increased megakaryocytes with normal
morphology and the absence of myelofibrosis. Chromosomal
studies showed no Philadelphia chromosome. A radiological
examination showed compression fractures of the vertebrae
and spinal cord compression. No underlying disease causing
a leukemoid reaction was detected. With iron replacement,
the hemoglobin level failed to increase over 12 g/dL.
Therefore, it was concluded to be a transition of PV to
CNL. After administration of hydroxyurea and
vertebroplasty, the symptom improved and the WBC count was
sustained below 40,000/microL.

Publication Types: Case Reports

PMID: 15683121 [PubMed - indexed for MEDLINE]

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  #9   ^
Old Wed, Jun-01-05, 06:17
Ironjustir
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Default Re: Asthma / allergies / erythrocytosis / increased red blood cells

  > Bone .. up .. boy

Yes, and you are the boy that it's up.

And I thought all the squirming that you were doing was for
being shown up for the inaccurate fraud that you are.
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  #10   ^
Old Wed, Jun-01-05, 06:17
Ironjustir
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Default Re: Asthma / allergies / erythrocytosis / increased red blood cells

  >Well .. YOU .. explain .. then ..
  >
  >If you are . sooooo .. wise ..

  >WHY .. did I .. post this on both leukemia lists and asthma
  >.. lists ..
?

  >WHY .. ?

Why? You'd post to a shopping list if it would get you
attention.

  >Pretty .. simple ..

Don't worry, we knew that about you after your first post.
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  #11   ^
Old Wed, Jun-01-05, 06:17
Aroberts
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Default Re: Asthma / allergies / erythrocytosis / increased red blood cells

"00doc" <forum~goheavy.com> wrote in message
news:wv-dncjA3bvxcQHfRVn-vQ~comcast.com...
  > ironjustiron wrote:
     >> ironjustice~aol.com wrote:
       >>> I suppose if one were to attempt to followup on the link
       >>> between increased blood cell mass / erythrocytosis .. one
       >>> might find a link then between INCREASED leukemia /
       >>> uncontrolled red blood cell production .. and asthma /
       >>> allergies .. ?
       >>>
       >>> Voila ..
     >>
     >> Voila, as in "how wrong can you get"?
     >>
     >> Neither leukemia nor myleloma present with increased blood
     >> cell mass/ erythrocytosis.
  >
  > That's OK. Neither does iron excess.
  >
  > It causes a lot of things - dementia, heart failure, kidney
  > failure, immunodeficiencies, liver failure - it goes on. it
  > can even in the end stages cause anemia. But it does not
  > cuase polycythemia.

Then perhaps it causes eggs and chickens...he seems to be
dwelling on that aspect....
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  #12   ^
Old Wed, Jun-01-05, 06:17
00doc
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Default Re: Asthma / allergies / erythrocytosis / increased red blood cells

ironjustice~aol.com wrote:
  > Mr.. manwithasthma is NOW .. a .. cancer .. specialist ..
  >
  > Jeez .. your abilities .. extend far beyond .. asthma ..
  >
  > Eh ..
  >
  > For .. sure ..
  >
  > Heh .. heh ..
  >
  > Stick .. to .. asthma ..

Oh, the irony.
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  #13   ^
Old Wed, Jun-01-05, 06:17
00doc
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Default Re: Asthma / allergies / erythrocytosis / increased red blood cells

ironjustice~aol.com wrote:
  > Excuse .. me .. ?
  >
  > Are you .. stupid .. ?
  >
  > You must .. BE .. stupid ..
  >
  > Another NAME .. for .. hemochromatosis .. IS ..
  > erythrocytosis ..
  >
  > Iron overload = erythrocytosis .. ask any blood donor
  > clinic ..

No it is not.

Erythrocytosis is the process of producing erythrocytes (red
blood cells). So right of the bat you are equating a noun
with a verb.

Polycythemia means increased red cell mass (and usually
increased hematocrit (percentage of the bllod that is RBC's)).

Hemochromatosis is a condition of excess iron accumulation. It
can be genetic or from environmental factors and the excess
iron deposition in the tissues causes dysfunction of many
organs. One of its symptoms is anemia, due to damage to
thebone marrow from the iron, not polycythema.

In normal people there is enough iron to make all the red
cells that you body wants and so the levels are regulated by
other means (mainly erythropoetin levels). Increasing the iron
does not drive increased production. The only time iron
influences red cell mass is when its absence prevents
production and results in amenia.

http://www.americanhs.org/whatisit.htm

http://digestive.niddk.nih.gov/ddiseases/pubs/hemochromatosis-
/index.htm#symptoms

http://www.mayoclinic.com/invoke.cfm?objectid=992CA155-2D99-4-
C3E-BDBF4F4470FE5B8F&dsection=2

http://www.cdc.gov/hemochromatosis/

You will note that none of these list polycythemia as a sign.

--
00doc
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  #14   ^
Old Wed, Jun-01-05, 06:17
Robert
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Default Re: Asthma / allergies / erythrocytosis / increased red blood cells

<ironjustice~aol.com> wrote in message
news:1117596137.375795.205270~g44g2000cwa.googlegroups.com...
  > Excuse .. me .. ?
  >
  > Are you .. stupid .. ?
  >
  > You must .. BE .. stupid ..
  >
  > Another NAME .. for .. hemochromatosis .. IS ..
  > erythrocytosis ..

Not even close. Maybe in your dellusional mind. Primary and
secondary polycythemias have nothing to do with iron directly.
The circulating cells may even be iron deficient as production
goes off the chart in comparison to iron supply. You can
simply be dehydrated causing a high hematocrit. Iron overload
is associated with refractory anemia and in the case of sickle
cell anemia, bone marrow failure. You simply don't know what
you are talking about.

  >
  > Iron overload = erythrocytosis .. ask any blood donor
  > clinic ..
  >
  > Who loves ya. Tom Jesus Was A Vegetarian!
  > http://jesuswasavegetarian.7h.com Man Is A Herbivore!
  > http://pages.ivillage.com/ironjustice/manisaherbivore DEAD
  > PEOPLE WALKING
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  #15   ^
Old Wed, Jun-01-05, 06:17
Robert
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Default Re: Asthma / allergies / erythrocytosis / increased red blood cells

<ironjustice~aol.com> wrote in message
news:1117601048.668355.30590~o13g2000cwo.googlegroups.com...
  > Well .. YOU .. explain .. then ..
  >
  > If you are . sooooo .. wise ..
  >
  > WHY .. did I .. post this on both leukemia lists and asthma
  > .. lists .. ?
  >
  > WHY .. ?

Because you can.

You are like a homeless man with a shopping cart full of
useless Pubmed references.

  >
  > Pretty .. simple ..
  >
  > And IF .. you .. DO .. 'know' .. WHY .. then .. why ..
  > didn't YOU .. enlighten .. your .. bro .. ARoberts .. ?
  >
  > Eh .. ?
  >
  > Who loves ya. Tom Jesus Was A Vegetarian!
  > http://jesuswasavegetarian.7h.com Man Is A Herbivore!
  > http://pages.ivillage.com/ironjustice/manisaherbivore DEAD
  > PEOPLE WALKING
  > http://pages.ivillage.com/ironjustice/deadpeoplewalking
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