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  #136   ^
Old Sun, Apr-02-17, 08:55
WereBear's Avatar
WereBear WereBear is offline
Posts: 9,531
 
Plan: Epi-Paleo/IF
Stats: 220/169/150 Female 67
BF:
Progress: 73%
Location: USA
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So this neurotransmitters thing is popping in my brain like popcorn.

Found a great article on Neurotransmitter Depletion:

Quote:
For years it has been known in medicine that low levels of Serotonin and/or Norepinephrine can cause many diseases and illness. Some of the diseases and/or illnesses caused by or associated with low levels of Serotonin and/or Norepinephrine include:

Depression/Moody
Anxiety
Panic Attacks
Insomnia/Sleep disorders
Premenstrual Tension
Fibromyalgia
Obesity
Anorexia
Bulimia
"Hypoglycemia"
Chronic pain states
Migraines
ADD/ADHD
Restless Leg Syndrome
In addition, over 60 diseases and illnesses may be caused by or associated with neurotransmitter deficiency. Low neurotransmitter levels is not only very common, it is epidemic.


And how do we get neurotransmitters? Nutrition.

Quote:
"How do the levels of serotonin and catecholamine neurotransmitters get to such critically low levels?" There are several explanations.

The first is that neurotransmitter depletion is nutritionally based. Neurotransmitters are made from amino acids that must be obtained from protein in the diet. In addition, amino acids, vitamins and minerals eaten in food are required for the creation of the neurotransmitters. If the diet is deficient, neurotransmitter deficiency develops.


I knew I was onto something big.
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  #137   ^
Old Mon, Apr-03-17, 10:42
sandy867's Avatar
sandy867 sandy867 is offline
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Posts: 4,312
 
Plan: LC/low Lactose
Stats: 304/290/130 Female 65 "
BF:
Progress: 8%
Location: PNW
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That is true. However, is it possibly that at a certain age, our ability to manufacture or deal with the same chemical pathways is reduced? That's what happens in Diabetes type II...there's plenty of insulin, but the body is more resistant to it. Essentially the tissues are older and less responsive. Fatty, old organs are a big issue, the liver for example.

One reason weight loss cures so many of those things.
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  #138   ^
Old Tue, Apr-04-17, 06:20
WereBear's Avatar
WereBear WereBear is offline
Posts: 9,531
 
Plan: Epi-Paleo/IF
Stats: 220/169/150 Female 67
BF:
Progress: 73%
Location: USA
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Quote:
Originally Posted by sandy867
However, is it possibly that at a certain age, our ability to manufacture or deal with the same chemical pathways is reduced? That's what happens in Diabetes type II...there's plenty of insulin, but the body is more resistant to it. Essentially the tissues are older and less responsive. Fatty, old organs are a big issue, the liver for example.


Good thinking. Since one of my problems was cortisol resistance. So it's not like only insulin can trigger resistance in high doses. My stressed system was giving my body all the symptoms of low cortisol; so when I discovered my cortisol tested high, it was a puzzle... until I found out about cortisol resistance, which I fixed with circadian rhythms reset techniques from Dr. Kruse.

And norepinephrine and adrenaline (epinephrine) are both hormones which act as neurotransmitters, too.

Still, I am responding so well to niacin, an amino acid that contributes to the creation of neurotransmitters, I think I am dealing with a failure in the supply chain. Without a good diet, we don't eat enough protein to make what we need. With sugar and wheat actually blocking the nutrients to make neurotransmitters, we are undercutting production that way, too. Which is how diet fixes things, certainly; many many people report better mood with low carb. Because they are finally making enough neurotransmitters.

Julia Ross's book, The Mood Cure, has a saga about how Prozac was being undercut by the amino acid tryptophan. Which worked better.
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  #139   ^
Old Tue, Apr-04-17, 06:38
tess9132 tess9132 is offline
 
Plan: general lc
Stats: 214/169/130 Female 5'3"
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Werebear - have you noticed a reduction in cellulite since you began niacin? It seems the more weight I lose, the worse my cellulite looks. I know cellulite partly comes from bad circulation and I was wondering if niacin flushing would help the fat on my legs and backside look better.
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  #140   ^
Old Tue, Apr-04-17, 17:46
WereBear's Avatar
WereBear WereBear is offline
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Plan: Epi-Paleo/IF
Stats: 220/169/150 Female 67
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Progress: 73%
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I don't know for sure, but it is great for circulation. My skin has never looked so happy.
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  #141   ^
Old Sat, Apr-08-17, 13:15
WereBear's Avatar
WereBear WereBear is offline
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Plan: Epi-Paleo/IF
Stats: 220/169/150 Female 67
BF:
Progress: 73%
Location: USA
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FAT seems to be the key; stuck at work, not hungry for lunch, so I had my lunch niacin dose with hot tea with hemp oil, which I keep in the work fridge as salad dressing. Seemed to work!

Thanks, teaser.
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  #142   ^
Old Mon, Apr-17-17, 12:06
WereBear's Avatar
WereBear WereBear is offline
Posts: 9,531
 
Plan: Epi-Paleo/IF
Stats: 220/169/150 Female 67
BF:
Progress: 73%
Location: USA
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As life challenges have been mounting (long overnight trip, DH got sick, still doing two people's jobs at work,) I have upped my daily niacin dose by 1k, for a total of 4k a day (adding one 500mg dose to each of my two daily meals.) It's been almost a week, there aren't any adverse effects, and it seems to be helping.

Caution: I was very sick for a very long time -- this is a high dose and not for everyone. In addition, I can back off if I continue to improve. But after feeling so darned good after going on Niacin Therapy, and keeping in mind the body's need does fluctuate, (according to the book I referenced in the first post on this thread,) I feel good about adding niacin when my body and brain are running low.

In brain effort alone I have been shifting into a higher gear. We are moving forward to the next level of our little home business: the scary one where you borrow enough money to set up manufacturing.

I don't think I could do this without the niacin Because even faced with this level of stressor, I'm still chillin' like a villain.

There was a long... discussion ... about the situation that led to this decision. Because both DH and I have been trying to manage things without taking such a big step, and I now had the clarity to sit him down and say, "That plan isn't working. We need a new plan."

Now that he and I are in agreement on this, I am managing to do all the things necessary to get this set up and started. And it does not faze me; I just do it. My own calm feeds into DH's calm, and vice versa.

This is extraordinary to me, because I was so used to a constant low hum of anxiety, which would ramp up into semi-panic state very easily. While I can still get stirred up and a little agitated, it's like setting a bottle of iced tea back on the table; it is shaken, but then calms down quickly.

I am amazed by myself... on niacin.
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