Active Low-Carber Forums
Atkins diet and low carb discussion provided free for information only, not as medical advice.
Home Plans Tips Recipes Tools Stories Studies Products
Active Low-Carber Forums
A sugar-free zone


Welcome to the Active Low-Carber Forums.
Support for Atkins diet, Protein Power, Neanderthin (Paleo Diet), CAD/CALP, Dr. Bernstein Diabetes Solution and any other healthy low-carb diet or plan, all are welcome in our lowcarb community. Forget starvation and fad diets -- join the healthy eating crowd! You may register by clicking here, it's free!

Go Back   Active Low-Carber Forums > Main Low-Carb Diets Forums & Support > Low-Carb Studies & Research / Media Watch > LC Research/Media
User Name
Password
FAQ Members Calendar Mark Forums Read Search Gallery My P.L.A.N. Survey


Reply
 
Thread Tools Display Modes
  #1   ^
Old Wed, Oct-25-17, 08:15
RawNut's Avatar
RawNut RawNut is offline
Lipivore
Posts: 1,208
 
Plan: Very Low Carb Paleo
Stats: 270/185/180 Male 72 inches
BF:
Progress: 94%
Location: Florida
Default Nutrient biomarker patterns and long-term risk of dementia in older adults

Quote:
Abstract

Introduction

Several nutrients may predict dementia risk. We characterized nutrient biomarker patterns, which integrate the complexity of nutrient exposure and biodisponibility associated with long-term risk of dementia in a large cohort of older persons, the Three-City study.



Methods

We included 666 nondemented participants with plasma measurements of 22 fat-soluble nutrients at baseline, who were followed up for 12 years for dementia.



Results

A “deleterious” pattern combining lower blood status in vitamin D, carotenoids, and polyunsaturated fats and higher saturated fats was strongly associated with a higher risk of dementia. Compared with individuals in the first quintile of the pattern score, participants in the highest quintile of score had an approximately fourfold increased risk of dementia (hazard ratio = 4.53 [95% confidence interval 1.99, 10.32], P for trend <.001) in multivariate models.



Discussion

A blood pattern reflecting lower status in several nutrients among nondemented individuals appeared strongly associated with the long-term risk of dementia in this cohort.






http://aanddjournal.net/article/S15...0086-9/fulltext
Reply With Quote
Sponsored Links
  #2   ^
Old Wed, Oct-25-17, 08:32
bkloots's Avatar
bkloots bkloots is offline
Senior Member
Posts: 10,147
 
Plan: LC--Atkins
Stats: 195/162/150 Female 62in
BF:
Progress: 73%
Location: Kansas City, MO
Default

Translation, please?
Reply With Quote
  #3   ^
Old Wed, Oct-25-17, 08:51
RawNut's Avatar
RawNut RawNut is offline
Lipivore
Posts: 1,208
 
Plan: Very Low Carb Paleo
Stats: 270/185/180 Male 72 inches
BF:
Progress: 94%
Location: Florida
Default

Quote:
Originally Posted by bkloots
Translation, please?


The people who had low vitamin D, carotenoids, and PUFA but high saturated fat in the blood got the most demented.

We know that low carb increases blood PUFA and decreases blood saturated fat, so this should be good news.
Reply With Quote
  #4   ^
Old Wed, Oct-25-17, 11:03
Meme#1's Avatar
Meme#1 Meme#1 is offline
Senior Member
Posts: 12,456
 
Plan: Atkins DANDR
Stats: 210/194/160 Female 5'4"
BF:
Progress: 32%
Location: Texas
Default

I wonder if there is a clear difference in people living in sunny areas v people living in less sunny places?
Reply With Quote
  #5   ^
Old Wed, Oct-25-17, 12:32
teaser's Avatar
teaser teaser is offline
Senior Member
Posts: 15,075
 
Plan: mostly milkfat
Stats: 190/152.4/154 Male 67inches
BF:
Progress: 104%
Location: Ontario
Default

Quote:
Originally Posted by bkloots
Translation, please?



Biodisponibility turns out to be bioavailability in french, if that's what you were wondering about.
Reply With Quote
  #6   ^
Old Wed, Oct-25-17, 19:45
deirdra's Avatar
deirdra deirdra is offline
Senior Member
Posts: 4,324
 
Plan: vLC/GF,CF,SF
Stats: 197/136/150 Female 66 inches
BF:
Progress: 130%
Location: Alberta
Default

Quote:
Originally Posted by RawNut
The people who had low vitamin D, carotenoids, and PUFA but high saturated fat in the blood got the most demented.
We know that low carb increases blood PUFA and decreases blood saturated fat, so this should be good news.
Of course the media and Ornish types will pick up on the high saturated fat in the blood and say don't eat animal fat.
Reply With Quote
  #7   ^
Old Wed, Oct-25-17, 20:28
Zei Zei is offline
Senior Member
Posts: 1,596
 
Plan: Carb reduction in general
Stats: 230/185/180 Female 5 ft 9 in
BF:
Progress: 90%
Location: Texas
Default

Which is unfortunate for those who follow their high carb plant eating styles because based on what RawNut said, low poly and high saturated fat in the blood is essentially a marker for eating high carbohydrate. Concerning sunny versus less sunny areas I'm not sure there would be a difference because so many people have erroneously been told by doctors to fear the sun, douse themselves in vitamin D blocking sunscreens (sun's UVB radiation gives us the vitamin D), to stay indoors during the middle time of day, the only time of day when UVB is available. All in the name of supposedly avoiding skin cancer while ironically increasing risk of more potentially lethal internal cancers due to the resulting vitamin D deficiency. Plus I read someplace that the vitamin D recommendations may be off by something like ten-fold due to a supposed mathematical calculation error. If so that would make current recommendations about ten times lower than people might actually need. As one of the findings of this study, vitamin D deficiency: not good.
Reply With Quote
  #8   ^
Old Thu, Oct-26-17, 08:54
WereBear's Avatar
WereBear WereBear is offline
Senior Member
Posts: 14,605
 
Plan: EpiPaleo/Primal/LowOx
Stats: 220/125/150 Female 67
BF:
Progress: 136%
Location: USA
Default

I go by the fact that for a millenia or so, we ran around basically naked under a tropical sun. When we moved closer to the poles, we had to eat lots of cod liver oil and other natural sources of D, and also got paler so we could still manufacture it despite being covered in clothing... Germans and Scandinavians became nudists.

On the advice of a knowledgeable friend, I have switched to topical D with magnesium; seems to work better, at least at the moment when I am dealing with a low point of my health journey.
Reply With Quote
  #9   ^
Old Thu, Oct-26-17, 08:55
WereBear's Avatar
WereBear WereBear is offline
Senior Member
Posts: 14,605
 
Plan: EpiPaleo/Primal/LowOx
Stats: 220/125/150 Female 67
BF:
Progress: 136%
Location: USA
Default

Carotenoids are plant pigments. I do a lot of berries and tomato sauce; seems to get along with me and there's lot of pigment there.
Reply With Quote
Reply

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off



All times are GMT -6. The time now is 11:46.


Copyright © 2000-2024 Active Low-Carber Forums @ forum.lowcarber.org
Powered by: vBulletin, Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.