Mon, Nov-15-10, 19:22
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Senior Member
Posts: 302
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Plan: Atkins
Stats: 149.6/143/130
BF:Stats not updated
Progress: 34%
Location: Israel
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I did find a lot on the net, I just don't understand a lot of it. I found some info on vitamins A and E but not D. The following show that Cholesterol is very important to those trying to conceive:
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HDL and fragmentation (embryo quality) in ivf is a negative correlation, the more HDL the less embryo fragmentation.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799562/
This one was very interesting:
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In ovarian follicles, non‐vascularized granulosa cells are in direct contact with the follicular fluid, but are separated from thecal blood capillaries by the basement membrane. This barrier behaves like a molecular sieve, which allows passage of protein in inverse proportion to molecular weight, but paradoxically not in inverse proportion to molecular size (Shalgi et al., 1973). In addition to this, in mice, this barrier has been found to be both charge‐ and size selective (Hess et al., 1998). Thus, a very specific composition of follicular fluid can be observed in mammals with molecules of lower molecular weight such as albumin being present in follicular fluid and higher molecular proteins are excluded (Andersen et al., 1976). In consequence of this observation, VLDL/LDL are excluded from the transfer and only HDL are present in follicular fluid of humans as shown in our study and by others (Simpson et al., 1980). Thus, only carotenoids and α‐tocopherol associated with the HDL fraction can be recovered in the follicular fluid as found by selective precipitation of the VLDL/LDL fractions of plasma lipoproteins.
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Both vitamin A deficiency as well as excess results in congenital defects in the embryo
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Although we were not able to find any differences in the concentration of carotenoids, retinol and α‐tocopherol in plasma and follicular fluid between women with different fertilization successes, a striking observation was the variability of the FF/P ratio of the investigated components in follicular fluid of women in which no pregnancy was established was double the one observed in those women in whom IVF treatment resulted in pregnancy. This would be supported by the observation that due to the molecular sieve of the blood‐follicular fluid barrier in healthy follicles only HDL are present (Jaspard et al., 1996). In cases of follicle and oocyte hypermaturity, however, VLDL and LDL particles can be detected. This indicates a disturbance of the molecular sieve causing differences in steroid metabolism that might negatively effect oocyte development (Volpe et al., 1991).
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http://humrep.oxfordjournals.org/content/18/6/1259.long
This one I did not have access to:
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Quote:
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Cholesterol, being the starting point of steroid hormone synthesis, is a long known modulator of both female and male reproductive physiology especially at the level of the gonads and the impact cholesterol has on gametogenesis. Less is known about the effects cholesterol homeostasis may have on postgonadic reproductive functions. Lately, several data have been reported showing how imbalanced cholesterol levels may particularly affect the post-testicular events of sperm maturation that lead to fully fertile male gametes. This review will focus on that aspect and essentially centers on how cholesterol is important for the physiology of the mammalian epididymis and spermatozoa.
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http://www.nature.com/aja/journal/v...aja201064a.html |
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Hi sondacop and shalom ..... RE: Fat Head the mobvie
Linear Mode
