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  #1   ^
Old Thu, Feb-16-17, 06:05
JEY100's Avatar
JEY100 JEY100 is offline
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Default President of World Heart Oganiztion speech on CVD

http://www.thefatemperor.com/blog/2...y-not-fat-ones-

Salim Yusuf, in a speech to cardiologists on results of large study, with data pointing to carbohydrates rather than fats (has details on the types of fats) in rates of CVD in 200 countries.

https://m.youtube.com/watch?feature...e&v=0sNqnAZTy4w

Last edited by JEY100 : Thu, Feb-16-17 at 06:12.
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  #2   ^
Old Thu, Feb-16-17, 08:17
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patriciakr patriciakr is offline
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Thanks for posting this link. Right up on my facebook page, and soon to be posted on my blog.
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  #3   ^
Old Tue, Feb-28-17, 06:34
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JEY100 JEY100 is offline
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MedPage Today headline:
Top Cardiologist Blasts Nutrition Guidelines

Salim Yusuf says new evidence fails to support many major diet recommendations.
by Larry Husten Cardio Brief

February 27, 2017

Quote:
One of the world's top cardiologists says that many of the major nutrition guidelines have no good basis in science.
"I'm not a nutrition scientist and that may be an advantage because every week in the newspaper we read something is good for you and the same thing the next week is bad for you," said Salim Yusuf, MD, DPhil,(McMaster University), at Cardiology Update 2017, a symposium presented by the European Society of Cardiology and the Zurich Heart House.

Yusuf presented evidence that many of the most significant and impactful nutrition recommendations regarding dietary fats, salt, carbohydrates, and even vegetables are not supported by evidence.

Yusuf's talk relied heavily on findings from the PURE study, a large ongoing epidemiological study of 140,000 people in 17 countries. Though PURE is an observational study, "its design and extensive data collection are geared toward addressing major questions on causation and development of the underlying determinants of cardiovascular disease."
Much of the data presented by Yusuf has not been published yet and should be considered preliminary, he said. In 2014 publication of the sodium results stirred considerable controversy.
The results from PURE will likely add fuel to the ongoing fiery debate over carbohydrates and fats. Yusuf displayed data showing that the incidence of cardiovascular disease in the PURE population increases as carbohydrate intake (as a percentage of total calories) rises.
"Previous guidelines said reduce fats and compensate for it by increasing carbohydrates ... and so essentially we've increased carbohydrate intake in most Western countries and this is likely damaging. We were in for a big surprise. We actually found that increasing fats was protective."

The PURE data show a steep increase in CV risk as carbohydrate intake increased beyond 55% of total energy. WHO guidelines state that up to 75% of energy can come from carbohydrates. "But that is wrong," said Yusuf.

Dietary Fat
"We actually found that increasing fats was protective," he said. Low consumption of total fat was associated with increased risk. Very high fat is also "probably bad," Yusuf said, based on earlier studies from Finland with people who had "extremely high fat levels, not the usual fat levels that populations consume."
No clear patterns emerged for different types of fats, Yusuf reported. Trends suggested that saturated fats were not harmful and perhaps even beneficial, while monounsaturated oils appeared beneficial. Polyunsaturated oils had a neutral effect, he said.
"You've got to think about the change in oils that have occurred in the world in the last 30 years," said Yusuf. "It was entirely industry driven. We went from natural fats, which are animal fats, to vegetable fats, because they [industry] can produce it and therefore charge for it, and this was swallowed hook, line, and sinker by the AHA, and the WHO just repeated it."

Yusuf also took aim at milk consumption trends in the US. "Even if you consume milk they want you to consume 2% or 1% of fat" but, he asked, "what is the evidence?" "A big, big, zero," he said. In fact, he said, there "really are no data at all to reduce the fat content of milk."
Yusuf came down squarely in favor of fats over carbohydrates: "Fundamentally, some fats are good, some fats may be neutral, but it's carbohydrates that are the worst thing." He offered a piece of advice: "so when you eat a hamburger throw away the bun and eat the meat."
Yusuf summarized the PURE findings, which found that saturated fats from dairy sources were protective and saturated fats from meats were neutral. White meat from chicken or fish appeared to have a beneficial effect, while red meat in moderate quantities was not associated with harm.
Yusuf volunteered a strong endorsement for Nina Teicholz, author of The Big Fat Surprise, who has been heavily criticized by the nutrition establishment for her defense of dietary fat. "She shook up the nutrition world but she got it right," said Yusuf.
"Why did we go wrong? We went wrong because of surrogate endpoints."

The demonization of fats -- saturated fats in particular -- stemmed from earlier observations linking saturated fat consumption to LDL levels. Yusuf reported that PURE confirmed this finding, but he also noted that the overall difference in LDL was small and that there was a large amount of variance. More importantly, randomized studies that have looked at fat reduction to reduce cardiovascular events have not shown benefit, except in cases where fat levels were extremely high, he said.
Yusuf said that the ApoB/ApoA ratio is a much more highly sensitive marker of risk. Data from PURE shows that this ratio goes up with carbohydrate consumption but is neutral with saturated fats or polyunsaturated fats and declines with monounsaturated fats.
Regarding salt consumption Yusuf restated findings from the previous published reports from PURE and the more recent report from a working paper from WHO. He said the low sodium position was based on the well-established relationship between sodium and blood pressure. But, he argued, the benefits of extremely low levels of sodium have never been tested in a randomized controlled trial. Further, since sodium is an essential nutrient it is inevitable that taking sodium levels too low will be harmful. He also pointed out that although reducing blood pressure through sodium reduction may turn out to be beneficial in people with hypertension, it is entirely possible that non-hypertensives will derive no benefits from sodium reduction but they may well be susceptible to the harms associated with low sodium levels.
Fruits and Vegetables
Yusuf also raised questions about fundamental recommendations that are almost never subject to critical scrutiny. "Where on earth did the concept that we should eat 5 servings of fruits and vegetables come from?" asked Yusuf.

"Why not 4, why not 3, why not 6, why not 7? Is it all fruits, is it all vegetables, is it what kinds of fruits, what kinds of vegetables?"
He reported that the PURE data found a neutral effect for vegetables, and that the literature is "really inconsistent." More importantly, he dismissed the idea that foods need to be judged based on their effect on health. "But I have to tell you, when it's regarding diet, neutral is good. You have to eat something. If you like it eat it. Not every food has to be good or bad."
Yusuf then pointed out that it is almost impossible for a large portion of the world to follow these fruit and vegetable recommendations. "Why are fruits and vegetables not consumed? All the guidelines are written by people sitting in Geneva or Dallas who are white, rich, and male. They are male, and so they don't know the cost of foods, they don't go do the grocery shopping. They're white and they only think of what happens in their countries." In high income countries like Canada and Sweden people spend only about 10% of their income on food. But in lower income countries like Pakistan, India, Zimbabwe, 65% of income is spent on food. It is then "no wonder that they're going to buy the cheapest food," he said. The cost of buying 2 servings of fruit and 3 servings of vegetables, as recommended by WHO, is completely unaffordable for many.


http://www.medpagetoday.com/Cardiol...977378d0r&pos=1 (subscription)

First outraged comment by Joel Kahn.For some reason, I cannot copy it, but expect more fireworks.

There is one common, but minor correction, to his speech added by Zoe Harcombe on her website. If you want to get right which Ancel Keys study was flawed and how, she explains here:

http://www.zoeharcombe.com/2017/02/...ountries-graph/

Last edited by JEY100 : Tue, Feb-28-17 at 11:22.
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  #4   ^
Old Tue, Feb-28-17, 08:17
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GRB5111 GRB5111 is offline
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Good summary, Janet. Couldn't access the Youtube link, but Ivor's site has the video. Bottom line here is that we still have no conclusive information regarding nutrition, mostly (on this forum) N=1 experiences, and until that changes, the debate will continue to rage regarding the traditional mythology stemming from Food Pyramid/MyPlate, vegetarianism/veganism, and those who follow a LCHF or Paleo approach. I even cringe with the acronym LCHF, as high fat is relative, and as noted in Yusuf's speech, amount of fat consumption can go from good to bad if it's too little or too much. How much is too much?
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  #5   ^
Old Tue, Feb-28-17, 10:11
tess9132 tess9132 is offline
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Thanks for posting this Janet. Very interesting. I've never heard of the World Heart Organization, but it sounds like a big deal, and to have its head challenging conventional nutritional information sounds like a really big deal.
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  #6   ^
Old Tue, Feb-28-17, 10:40
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Quote:
Yusuf came down squarely in favor of fats over carbohydrates: "Fundamentally, some fats are good, some fats may be neutral, but it's carbohydrates that are the worst thing." He offered a piece of advice: "so when you eat a hamburger throw away the bun and eat the meat."


Wow. That's some line drawn in the sand there.
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  #7   ^
Old Tue, Feb-28-17, 15:16
JEY100's Avatar
JEY100 JEY100 is offline
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An open CardioBrief link, and the two comments there are supportive. http://cardiobrief.org/2017/02/27/t...tion-guidelines
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  #8   ^
Old Fri, Mar-03-17, 06:55
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JEY100 JEY100 is offline
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MedPage has all our favorite CICO diet "experts" like David Katz in one article blasting away at Dr. Yusuf.

This is War...they said it, not me.

Quote:

Fat Wars: Diet Docs Have Salim Yusuf in the Cross Hairs
More meat, less veggies? Nutrition experts respond

by Crystal Phend


A public attack on diet dogma from fats to vegetable intake got leading cardiologist Salim Yusuf, MD, DPhil, into scalding water with nutrition experts.

Yusuf, speaking at the Cardiology Update 2017 symposium, noted that he was no expert on nutrition but argued some controversial points for heart health, including:

Greater fat intake (even saturated fat) was protective
More carbohydrates were harmful
Higher fat dairy was beneficial
Saturated fat from meat was neutral
More vegetable intake wasn't any better

These conclusions were based mainly on unpublished, preliminary results of his group's ongoing PURE study. That epidemiological look at 140,000 people in 17 countries was designed to address causation and underlying determinants of cardiovascular disease, he said in the talk, which has been taken down by the official conference YouTube page but is still available elsewhere.

While Yusuf is no stranger to controversy, having released hotly-debated conclusions on sodium from PURE already, the diet discussion was deemed "irresponsible" this time. Plant-based diet proponent Joel Kahn, MD, even called some of the comments "slander" and called for an apology.

"Bizarre" and "misguided" was the description by David Katz, MD, MPH, president of the American College of Lifestyle Medicine, writing in Forbes. He argued that "we have no business seeking expert nutrition guidance from non-experts."

Whatever else, Yusuf's "comments are premature and not helpful," Marion Nestle, PhD, MPH, of New York University in New York City, told MedPage Today. "In view of the fact that he is basing his comments on unpublished work, it's not possible to address his specific concerns.

"But in general, it is well established that healthy diets based largely on plant foods are associated with a lower risk of chronic disease. The specific contribution of fats and sugars is more difficult to establish because so much depends on the number of calories consumed with them."

Yoni Freedhof, MD, of the University of Ottawa, agreed. "I'm not sure that trading premature and perhaps dogmatic low-fat advice, for premature and perhaps dogmatic high-fat advice is supported by the medical literature to date. Seems to me that the most evidence-based advice around fats would be to try to replace saturated fats with unsaturated, to avoid trans, and that if the choice is between saturated fats and refined carbohydrates, the fats are the better choice."

More to the science, Katz broke down what he called a logical fallacy in conclusions such as that meat, but not vegetable intake, is protective against heart disease in a post on LinkedIn.
"Poor countries traditionally eat little meat, and have a very high intake of carbohydrate. In some cases, they have a high intake of fat, too, but from plant sources rather than animal; this is true, for instance, in rural Greece and other Mediterranean populations. In almost no instance do they have a high intake of saturated fat. We know, because it's on prominent display, that when countries with traditionally high-plant, high-carbohydrate, low-saturated-fat and low animal food diets switch to the more 'affluent' pattern of eating more meat, their rates of obesity and chronic disease rise. This is perfectly clear in both India and China."

Katz added that "we might ask: well, what happens within a given population, where access to medical care is the same, when diet is changed? We have the answer. Randomized trials including the Lyon Diet Heart Study, PREDIMED, and others have shown, over a span of years and in multiple countries, that shifts to more plant foods, unsaturated oils, and less meat reduce heart disease, other chronic disease, and rates of premature death from all causes."
Vegan diet proponent and prominent cardiologist Kim Williams, MD, of Rush University Medical Center in Chicago, further challenged the conclusions:

"I have the same concerns that Salim Yusuf actually expresses – this is not randomized data, so it can be hypothesis generating but not prescriptive, particularly because many of his statements conflict with existing scale. Some of these dietary issues may simply be distortion of scale – differences that are too narrow to show a clinical difference. For example, the PURE study had the highest category as >4 servings of vegetables and that was only a small fraction of the population (9,000 out of 150,000).
"But a recent meta-analysis of prospective trials with over 1,000,000 total subjects demonstrated that consuming 10 servings (200 grams per day) has a dramatic reduction in mortality, stroke, and cardiovascular outcomes.
"Thus, the 'dose' in the PURE study may be too small, with alternative food stuffs, such as animal protein, not varied enough between groups to demonstrate a difference. In other words, if you want to show improvement with vegetables, it may be best to study vegetarian versus non-vegetarian populations, rather than smaller variations among omnivorous populations."


http://www.medpagetoday.com/Primary...101703d0r&pos=0

Last edited by JEY100 : Fri, Mar-03-17 at 08:25.
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  #9   ^
Old Sun, Mar-05-17, 09:38
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Dr Eades annotated comments on the speech.

Dr. Salim Yusuf and the PURE study
Saturated fat isn't bad for you


https://proteinpower.com/drmike/201...the-pure-study/
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  #10   ^
Old Sun, Mar-05-17, 11:58
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GRB5111 GRB5111 is offline
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Another good response by Dr. Eades. The statement "the blades come out" causes one to wonder about how Yusuf's observations directly threaten the critics who have responded so negatively. If this were treated purely as a scientific pursuit by considering potential plausible hypotheses, one would hope that all hypotheses would be considered until proven right or wrong. Any other response neglects any true, unbiased scientific consideration and points to biased agendas being in play. This is nothing new when it comes to nutrition arguments, but these polar opposite reactions confuse many and delay careful consideration of the knowledge and next steps required to get to the truth.
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Old Sun, Mar-05-17, 12:01
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patriciakr patriciakr is offline
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These days I'm surprised someone hasn't simply said this offends me and expected that to carry as much weight as scientific debate.
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Old Sun, Mar-05-17, 13:06
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At least one of them could have said "association is not causation." If their career wasn't based on the the opposite being true.

For Nestle's idea of sugar vs. fat's role being confused by calorie intake--okay, but if you give her that, she has to give on a low carb diet the possibility that it might be heart protective. How's this, a diet of 80 percent animal fat vs. one that's 80 percent refined sugar. Which do you think will be harder to get past an ethical review board? I think we're finally to the point where the sugar diet would be a harder pass.
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Old Sun, Mar-05-17, 13:33
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I HOPE we're finally to the point where the sugar diet would be a harder pass.
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Old Sun, Mar-05-17, 15:11
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Quote:
Originally Posted by patriciakr
These days I'm surprised someone hasn't simply said this offends me and expected that to carry as much weight as scientific debate.


Sadly true.
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  #15   ^
Old Wed, Mar-15-17, 05:41
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JEY100 JEY100 is offline
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The Fat Wars continue on MedPage.

Fat Wars: An Apology and Clarification Over Diet Snafu
Salim Yusuf and Zurich Heart House respond

Quote:

by Crystal Phend
Senior Associate Editor, MedPage Today
March 14, 2017
From the "oops" department, cardiologist Salim Yusuf, MD, DPhil, apologized for maligning the Seven Countries diet study in the controversial diet talk he gave at the Zurich Heart House, which in turn explained it should never have publicly released the video.
However, neither walked back the substance of the talk at the Zurich Heart House's Cardiology Update 2017 symposium. Yusuf's discussion generated backlash from the nutrition community, with many finding fault with his conclusions on dietary fat, carbohydrates, meat, and the general state of diet science.
See the full story here on Yusuf's talk; and here was the response from the nutrition community.
In a letter posted on the Zurich Heart House site from its leaders and Yusuf, the following explanation and apology was given:
"[Yusuf] explicitly declined to give permission to video tape, reproduce or broadcast his talk on diet and cardiovascular disease as it included preliminary and unpublished analyses from the large PURE study that he and about 200 investigators have been conducting for over 12 years. These analyses are ongoing and it is expected that the papers from the study will be submitted for publication soon after extensive checks, updates of follow up data and further analyses. It is wisest for commentators to wait for the publication to objectively assess the detailed methods and the findings and also place it in the context of meta analyses or summaries of other similar studies. The Zurich Heart House apologizes for inadvertently video taping the talk by Prof Yusuf and placing it on YouTube without explicit permission. The title of the YouTube post was not provided to Professor Yusuf and he was not aware of it until after it was posted. The video was immediately removed from YouTube by ZHH and joint efforts were made to ban the copied content.
"Professor Yusuf acknowledges that he made an error in one part of his talk. He had concerns about an analysis published by Keys based on data from governmental information from SIX countries. (A careful analysis of the data published by Keys and the discrepancies are described by Zoe Harcombe on Twitter).
"Professor Yusuf mistakenly referred to this analysis from SIX countries as being from the SEVEN countries study. His remarks were not intended to refer to the SEVEN countries study. For that, he apologizes to the investigators of the SEVEN country studies."
Plant-based diet proponent Joel Kahn, MD, who in his post on Medium had labeled some of the comments regarding the Seven Countries study "slander" and called for an apology, said the letter was a step in the right direction. Still, Kahn wasn't fully satisfied.
"It is insanity that the Zurich Heart House [ZHH] still uses a link to explain the mess via Zoe Harcombe, PhD, who maintains in the link that Dr. Keys fudged data or other words similar," he said in an email to MedPage Today. "How can an academic institution like ZHH use a blogger and not someone like Henry Blackburn, MD, of the University of Minnesota, still an active researcher for the Seven Countries Study at age 92? ZHH's effort was anemic."
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