Dr. Thomas Dayspring says ldl particle number and apo b the numbers to watch and that both large and small ldl cause disease. Other people say large ldl benign or even protective. What do you think?

https://www.lipidcenter.com/pdf/Und...pid_Profile.pdf

https://www.youtube.com/watch?v=fuj6nxCDBZ0

Have you seen the Ivor Cummins Cholesterol Conundrum video? He shows some data showing that the correlation of Ischemic heart disease with triglycerides or with Apo B is greatly attenuated when fasted insulin is below 12. This is around the 50 minute mark. This is only correlation, but it seems plausible. And it's a very strong correlation, when both Apo B or triglycerides X insulin is taken into account. High Apo B plus high insulin shows 11 times the disease as low Apo B plus low insulin, but High ApoB plus low insulin only shows 1.5 times the disease.

If I had a choice between getting insulin down to ideal levels, or Apo B down to ideal levels, but not both, which one should I choose? I'd probably choose insulin, it's a more obvious target, it's easier to think of ways to get that lower.

But that's all off of one study on heart disease in Quebec, so my preference might be a little premature.

Thanks teaser,
I'll watch it right now. I read Dayspring's https://www.lipidcenter.com/pdf/Und...pid_Profile.pdf
and he says particle number and APO B are as important as inflammation.

While my inflammatory markers were nil my LDL particle number was very high, APO B high, cholesterol went from 160 vegetarian to 323 first year keto. Dayspring says 1/3 of low carb people will do this and need to get the numbers down although in all cases low carb helps.

I've switched from coconut oil to avocado oil but what else can I do, should I do?

Have you read this teaser? I'm now working through Attia's series on cholesterol: http://eatingacademy.com/nutrition/...lesterol-part-i

Last year after one year keto my TC-323, HDL 85, LDL 183/mainly large, APO B 132, trig 128 with NO inflammatory markers-the good news.

Made changes: cut coconut oil and replaced with avocado oil-lots, reduced cheese somewhat (yumm cheese), switched from a high fat keto diet which made me feel bad anyway to an all I wanted protein diet and added 500 mg niacin before bed, added 100mg tocotrienols at dinner.

Two year mark using machine at work non fasting but before dinner, my TC-175, HDL 88, LDL 71, Trig 80. Funny the night before I also tested but after dinner and got TC-155, HDL 68, LDL 59, and because I ate trig 141.

Wow, don't know if it's a two year adjustment to correcting early glucose problems that led to the improvements, reducing fat somewhat and increasing protein, meds, or the effects of different oils in the diet make a striking change immediately.
Leslie

I wonder sometimes if massive amounts of coconut oil aren't a bit of a load on the liver. MCT's in excess of immediate energy needs still have to be processed by the liver, what isn't oxidized or exported as ketones is used to synthesized the longer chain fats that we store, and that means increased VLDL/triglyceride production. With long chain triglycerides, chylomicron formation is handled in the gut--and chylomicrons are the largest, "fluffiest" way to transport dietary fat in the blood--trading VLDL for chylomicron might equal a lower particle count.

Not excessively in all cases, but even a very high carbohydrate intake doesn't seem to be excessive in every case, judging from some individual/population health results.

Glad to hear things got better. No ApoB, but judging by the other numbers, I guess that's probably lower, too.

Probably the niacin had a pretty big effect. Dr. Davis used to recommend it, but I don't think he does anymore.

Thanks for this link. I really liked his presentation.