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  #1   ^
Old Mon, Nov-11-13, 13:22
Plecto Plecto is offline
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Default Trouble understanding cholesterol, LDL and HDL

Hi. I'm trying to understand what cholesterol, LDL and HDL is. I tried getting the information I wanted on wikipedia, but it's so confusing. What I understand is that cholesterol is the name of a single organic molecule and this is quite easy to understand. What I don't understand is when people start talking about "LDL-cholesterol" and "HDL-cholesterol". LDL stands for "Low-density lipoprotein" and is one of five groups of lipoprotein (one of the other being HDL). "LDL transports lipids such as cholesterol and triglycerides" wikipedia says, so why do they call it "LDL-cholesterol"? It would be like saying "insulin-glucose". I did some further reading about chylomicron which is yet another of these lipoprotein groups. Chylomicron is a group of small particles that consists of (among others) 85-92% triglycerides and 1-3% cholesterol, this makes so sense. Is one group of lipoproteins transporting another group of lipoproteins? Further reading about Very Low-Density Lipoprotein tells me that VLDL is also used to transport cholesterol and fats and is made in the liver BY fats and cholesterol? So now we have a lipoprotein that transports lipoproteins and is made by lipoproteins I'm so confused.
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  #2   ^
Old Mon, Nov-11-13, 13:37
Nancy LC's Avatar
Nancy LC Nancy LC is offline
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I take it you're trying to understand what it is versus what effect it has?

I think most of us concern ourselves with what effects it does or doesn't have, versus how it is created and utilized in the body. For that, I suppose you'd need a biology textbook.

If you want to read some of the controversy over what it does, then the articles linked in my signature might help.
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Old Mon, Nov-11-13, 13:52
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JEY100 JEY100 is online now
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In addition to Nancy's great list of articles, Peter Attia, MD wrote a 10 part series on cholesterol, which begins in part 1 to explain there are even two kinds of cholesterol, and in part 2 that there many types/sizes of ApoA and B-Lipoproteins, and each part of the series became progressively more complicated. I gave up, but maybe you can find your answers here:

http://eatingacademy.com/nutrition/...lesterol-part-i
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Old Mon, Nov-11-13, 14:09
Plecto Plecto is offline
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I am interested in the cholesterol controversy, but the purpose of this thread is just to understand what type of substances we are talking about and what function they have. I don't need a biology textbook, I just want a quick overview
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