http://sci-hub.tw/10.1001/jamainternmed.2018.2920


Woo has been doing some criticism of this Kevin Hall, Rudy Liebel, Stephan Guyanet critique of low carb claims. I yoinked the title for this thread from label for the link for the paper.

http://itsthewooo.blogspot.com/2018...a-and-risk.html

Her latest post addresses failure of insulin to correlate with weight gain. She goes into more detail, but anybody familiar with the idea of a personal "fat threshold" beyond which insulin resistance/type II diabetes are liable to develop should see the problem. Once a person's adipose tissue grows to the point where it's hitting against their personal potential for fat growth, fat trapping is compromised. Fat starts to accumulate where it shouldn't, in the liver, pancreas and visceral area. Insulin resistance increases, insulin levels increase. This may serve to push subcutaneous fat to grow a little further, but since they're near their potential growth, the insulin isn't as effective. Some type II's will get to the point where they're losing weight, if they don't take insulin--they may be still producing enough insulin to be hyperinsulinemic, but due to insulin resistance, no longer enough to avoid losing calories in the urine etc.