That is a huge dose of Cytomel and the usual person does not take this much unless they have an RT3 problem. Do you have RT3? I don't even have a thyroid and take 40 mcg a day split dose. Do not attempt to self dose Cytomel-it can cause heart palpitations and other symptoms and is easily overdosed and can worsen an already diagnosed heart condition. The dosage is based on your lab results and free T3 level along with your symptoms. Cytomel is a T3 med and you will feel it's effects right away so sublingual is not necessary you might experience palpitations from it hitting your system rapidly. T4 meds are the ones that take a few weeks to notice any effects.

I thought I should point out this thread is 7 years old.

Excess T3 has some definite symptoms. It'd be a hard drug to purposefully OD on because those side effects are so unpleasant.

I just started on Cytomel tuesday of this week and insisted on it with me doctor. My fatique and muscle weakness was staggering. I had foggy thinking and kept gaining weight. Well 4 days into it I feel great. I am convince that I do not convert T4 to T3 very well, thus the symptoms. Getting T3 to suppliment my synthroid, which he reduced so I would not be over medicated) has made a huge huge difference in my daily function.
I take .112 Synthroid and .25 Cytomel. Now I ask to be retested in 1 month and to include a test of my Free T3, that that runs around in your blood) and will go from there.

This is what I hope to accomplish when I see my doctor in a month. I am monitoring how I feel with the new meds. I dont care what the numbers say, what I care about is how I feel and I want to optimize how I feel. So at the end of this month, I want to consider upping or reducing the t3 depending on how I feel because that is what I think is most important. I have switched my diet also to more protein and removed as much simple complex carbs as I can (you still need some). From what I have read protein helps your body convert the T4 to T3 and I also added Vitamin D3 to assist in the absorbsion of Calcium and assist in the t4 conversion. My doctor,, well he only knows what he learned in med school and though he is willing to let me direct my care, he is not a believer that I needed T3.

I suspect I will be finding a specialist who can really work with me.. YOu know this is the rest of my life and I want to feel like living it.

Good luck, Kalaiala. I hope you post your results when you get retested.

I dont know how Canada works, but I would go to an Endo or another doctor. I started taking Cytomel 1 week ago. Immediately my energy level went back to normal, my head cleared up, my mucsle and joint pain eased greatly. I had to talk my doctor into Cytomel and he reluctantly agreed to give it to me saying all I needed was my Synthroid reduced and I would feel better. I reminded him of a conversation we had a couple years ago when I was taking Armour thyroid and he said I was not converting T4 to T3 well. He didnt have my free T3 results, he only had my tsh and was going on that. He had have the picture! I retest in 3 weeks (my request) because I want to feel optimal not "in a range". I want to get the exact mix of T3 and T4 so I feel like a person instead of a limp zombie. Stand up for yourself, it's your life! I also started eatting more protein and less simple carbs and that has helped also. I just recently added Vitamin D3 to my diet. I am still reading books on this and looking for ways to feel better. DO NOT just accept that your "numbers" are good. Adjust your meds to get optimal results in how you feel. The TSH test was developed and accepted as the "best practice" in 1974. Come on.. times have changed. To many people are suffering. Ok I will get off my soap box!