Fri, Jul-13-12, 13:29
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Senior Member
Posts: 10,116
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Plan: Atkins
Stats: 199/000/000
BF:
Progress: 100%
Location: Southern California
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Quote:
Originally Posted by Teaser
That's from the wikipedia entry for the citric acid cycle. The citric acid cycle chews up NAD+ and spits out NADH... which should increase production of beta-hydroxybutyrate from acetoacetate... but that might not make sense, since glycolysis would produce NADH, too. Can't say I really understand all this yet.
Quote:
The term redox state is often used to describe the balance of NAD+/NADH and NADP+/NADPH in a biological system such as a cell or organ. The redox state is reflected in the balance of several sets of metabolites (e.g., lactate and pyruvate, beta-hydroxybutyrate and acetoacetate), whose interconversion is dependent on these ratios. An abnormal redox state can develop in a variety of deleterious situations, such as hypoxia, shock, and sepsis. Redox signaling involves the control of cellular processes by redox processes.
Would levels of lactate and pyruvate production have an effect, since in a carb-adapted state they'd compete for reaction with NAD+ or NADH? So you get this weird thing where increased availability of glucose in the cell actually increases use of acetoacetate? At least in muscle cells.
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Teaser, I am not quite sure I understand all this, but somewhere in this discussion, in my mind, I hear the argument of the LC weight lifters saying "That is why we have to carb up after an intense workout so we can build more and better defined muscle or it is toned and sleek, but not 'chisled'."
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