Have you seen the recent critique of the Optimal Diet posted on the Perfect Health Diet site?
http://perfecthealthdiet.com/?p=1077
The author points to what he sees as an inability of the body to make sufficient mucus (which is made up of sugars) without adequate carbohydrates, and points to the role of mucus in lubricating the colon and gastro-intestinal cancers in people eating OD.
See also the comment by "Jane" who has read some of Kwasniewski's articles in Polish and says that there he advocates ratios of 0.6-0.8P : 2F : 0.8-1.5C for the long term and that the ratios 1P : 2.5-3.5F : 0.5C should be used only over the introductory phase of the OD and not maintained beyond that.
Further down there is a comment by the website owner, Paul Jaminet:
"... As the first really popular low-carb high-fat diet, the ODers acted as guinea pigs for the rest of us. We should learn what we can from them and fix their mistakes. I still believe in high-fat diets."
Another contributor, Lacie, reminds readers that the Polish eat a lot of "highly processed meat" (AGEs, nitrates and other preservatives) and that this is a likely source of GI cancers.
The discussion is on-going at the Perfect Health Diet website. The big deficiency in the entire discussion is the absence of any reference to the Evolutionary Health Principle. Nothing in biology (and human health is part of biology) makes sense except in the light of evolution and so the Principle is the essential theoretical paradigm for determining the best behaviours for human health. The Perfect Health Diet lacks a theoretical basis and is based on no more than a collection of anecdotes and theory-free research cobbled together in a way that suits the prejudices, knowledge and ignorance of the cobbler.