What you do between fasting is just as important as the fasting. Maybe more so. I don't have anywhere near Jimmy's issues, at least for bodyweight, but one problem I find with intermittent fasting is that some forms of it can throw me out of whack on my ketogenic diet. I don't measure ketones, but the subjective experience that I blame keto for--more energy, better mood, less social anxiety--can get thrown out of whack. Often I'll feel better during the fast--but because I'm basically in maintenance, the fasts mean that when I do eat, I'll need to eat more, and of course that means higher insulin even if it's ketogenic food, increasing appetite even further, so I'll feel better fasting but a little worse when I do eat. For me, out of ketosis can make for binges even on ketogenic food, although if I stick to the ketogenic food, the binging subsides quickly enough. The binges don't actually make me gain weight, but the mood changes/decreased energy from being out of ketosis are annoying.
I think Jimmy needs as much accountability as possible. For his first year of nutritional ketosis, he measured, weighed, took blood and ketone measures several times a day. Every time I hear him on a podcast talking about dangers of orthorexia, talking about how every morsel shouldn't be weighed--no. Weighing out your meat and butter is orthorexic if you're an underweight teen. If you're a cancer patient? Have epilepsy? Find that weighing and measuring and eating consistently keeps you from binges? Are diabetic? Sometimes being really uptight is what works. That year long experiment is what worked most consistently for Jimmy, people focus on what happened during his lazier keto period. I see him criticized on facebook and other places for his egg-fasting experiment as well. That's a case where strict rules about food, eggs, cheese and butter in defined ratios, allowed him to lose weight. It's really a very simplified keto approach--not one more crazy thing he tried, but more evidence that a keto diet can work for the guy if he applies it properly. My only problem with egg fasting is throwing in a little spinach would make for a much better omelet, and probably not hurt anything.
It's really easy to get lazy with keto, and that's fine for a lot of people. For me--if I haven't weighed out some hamburger for a few months, and want to tighten up, and go to weigh out four or five ounces, I'm astonished and dismayed at how little meat it looks like. In a couple of days, if I'm consistent, my appetite readjusts and it seems like plenty for a meal. For stricter ketogenic ratios, I just don't think anybody can get there by eye. If you're in a state where it takes a larger portion to satisfy, maybe portions look smaller, that's how it seems to work for me.
I don't really think Jimmy's problem is insulin resistance. Earlier on in his blog, Jimmy worried about hypoglycemia, one time he ate pizza slices in the teens as an "experiment" and his blood glucose barely budged. That's not insulin resistance--if I had to guess I'd say it was seriously depleted fat cells due to a weight loss of well over a hundred pounds, that were particularly insulin sensitive due to that depletion. The one fasting insulin measure I've seen Jimmy report was 15, that's high enough for somebody like Dr. Davis to be concerned, he advises single-digits, but for the overweight population, it's not a real big number.
https://www.youtube.com/watch?v=sXbV0gxRfPo&t=254s
Here's another video somebody posted that shows the results of Jimmy's year long affair with tracking/nutritional ketosis.
A high ratio ketogenic diet is something I find useful, but it can't be done casually. If I eat Atkins or page 4 style, but add all the fat bomb and heavy cream treats I want, I get fatter. If I eat to strict ketogenic ratios, and am careful with my protein portions, I can enjoy liberal amounts of heavy cream etc. without weight gain. Adding fat calories without reducing carb or protein calories will increase the insulin response, replacing protein or carbohydrate calories with fat calories will decrease it.