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Old Fri, Jul-26-02, 16:00
Voyajer's Avatar
Voyajer Voyajer is offline
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Default Study shows Saturated Fat not linked to Diabetes

So why have they been putting diabetes patients on low-fat diets?

Am J Clin Nutr 2001 Jun;73(6):1019-26

Dietary fat intake and risk of type 2 diabetes in women.

Salmeron J, Hu FB, Manson JE, Stampfer MJ, Colditz GA, Rimm EB, Willett WC.

Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston 02115, USA.

BACKGROUND: The long-term relations between specific types of dietary fat and risk of type 2 diabetes remain unclear. OBJECTIVE: Our objective was to examine the relations between dietary fat intakes and the risk of type 2 diabetes. DESIGN: We prospectively followed 84204 women aged 34-59 y with no diabetes, cardiovascular disease, or cancer in 1980. Detailed dietary information was assessed at baseline and updated in 1984, 1986, and 1990 by using validated questionnaires. Relative risks of type 2 diabetes were obtained from pooled logistic models adjusted for nondietary and dietary covariates. RESULTS: During 14 y of follow-up, 2507 incident cases of type 2 diabetes were documented. Total fat intake, compared with equivalent energy intake from carbohydrates, was not associated with risk of type 2 diabetes; for a 5% increase in total energy from fat, the relative risk (RR) was 0.98 (95% CI: 0.94, 1.02). Intakes of saturated or monounsaturated fatty acids were also not significantly associated with the risk of diabetes. However, for a 5% increase in energy from polyunsaturated fat, the RR was 0.63 (0.53, 0.76; P < 0.0001) and for a 2% increase in energy from trans fatty acids the RR was 1.39 (1.15, 1.67; P = 0.0006). We estimated that replacing 2% of energy from trans fatty acids isoenergetically with polyunsaturated fat would lead to a 40% lower risk (RR: 0.60; 95% CI: 0.48, 0.75). CONCLUSIONS: These data suggest that total fat and saturated and monounsaturated fatty acid intakes are not associated with risk of type 2 diabetes in women, but that trans fatty acids increase and polyunsaturated fatty acids reduce risk. Substituting nonhydrogenated polyunsaturated fatty acids for trans fatty acids would likely reduce the risk of type 2 diabetes substantially.

From full text:

When animal and vegetable fats were both included in the same model with intake of trans fatty acids and known risk factors, animal fat was not associated with diabetes risk....

Saturated and monounsaturated fatty acid intakes were not significantly related to diabetes risk when compared with an equivalent amount of energy from carbohydrate ....

Our results regarding the lack of association with total fat .... are also consistent with recently reported findings in a large prospective study of men ....

Last edited by Voyajer : Fri, Jul-26-02 at 16:08.
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