Thank you all for the advice. For some reason my last dr. convinced me that Depo was a good choice because it would help shrink my fibroids, no ovulation, less ovarian cysts, etc. I just started Yasmin last week and so far so good. I had an acne breakout this past weekend but can't say for certain if it's related to the pill or something else. I have finally stopped spotting after 3 months, which is in of itself a victory. I am going to be seeing a new PCP this year and hope to get a full reproductive/endocrine evaluation. Happy New Year everyone!