Wow, no I have never thought of that. I'll have to start paying attention. I have noticed I used to get a buzz, but now I just get tired. Figured it was age. I also use 2x as many painkillers (ibuprofin, goody's) to get rid of aches than a few years ago. I wonder if that dr who wrote the thyroid book, (Dr. Blanchard?) would be interested if you wrote and asked him?