You actually have a choice as to what you focus on. You can celebrate your weight loss or you can bemoan your loose skin and the additional pounds you would like to lose. I don't understand why your doctor prescribed orlistat. As Liz said it could be contributing to your depression and also you have been very successful by diet alone. Everything I have heard about this drug suggests that it is a nasty drug. You may feel miserable right now but there are things you can do to turn your attitude around and find the positives in what you have accomplished. I plateaued at a 70 pound weight loss for a long time and then I lost the rest of it. All the time I figured that at least things were better than when I started. The plateau didn't feel like a failure to me. It felt like the success that it was.

Jean