Hi everyone, I am so happy to have people to talk to about PCOS. I was diagnosed about 3 months ago. I am now taking 850 mg of Glucophage 3 times a day. Luckily, my periods in the last 3 months have become more regular, but I swear I am having more major mood swings than ever. I used to have really bad PMS, now it seems I am really depressed around the time I am suppossed to ovulate (14 days after the first day of my period). Has anyone else experienced more depression while your body was getting acclimated to the Glucophage? I know it's because my hormones are all crazy and out of whack, but I've spent all weekend crying over absolutely nothing! Thanks so much, I feel better already!